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Items: 1 to 20 of 221


A novel duodenal iron-regulated transporter, IREG1, implicated in the basolateral transfer of iron to the circulation.

McKie AT, Marciani P, Rolfs A, Brennan K, Wehr K, Barrow D, Miret S, Bomford A, Peters TJ, Farzaneh F, Hediger MA, Hentze MW, Simpson RJ.

Mol Cell. 2000 Feb;5(2):299-309.


A rapid decrease in the expression of DMT1 and Dcytb but not Ireg1 or hephaestin explains the mucosal block phenomenon of iron absorption.

Frazer DM, Wilkins SJ, Becker EM, Murphy TL, Vulpe CD, McKie AT, Anderson GJ.

Gut. 2003 Mar;52(3):340-6.


Iron overload in adult Hfe-deficient mice independent of changes in the steady-state expression of the duodenal iron transporters DMT1 and Ireg1/ferroportin.

Herrmann T, Muckenthaler M, van der Hoeven F, Brennan K, Gehrke SG, Hubert N, Sergi C, Gröne HJ, Kaiser I, Gosch I, Volkmann M, Riedel HD, Hentze MW, Stewart AF, Stremmel W.

J Mol Med (Berl). 2004 Jan;82(1):39-48. Epub 2003 Nov 15.


Effect of iron deficiency on placental transfer of iron and expression of iron transport proteins in vivo and in vitro.

Gambling L, Danzeisen R, Gair S, Lea RG, Charania Z, Solanky N, Joory KD, Srai SK, McArdle HJ.

Biochem J. 2001 Jun 15;356(Pt 3):883-9.


Intestinal expression of genes involved in iron absorption in humans.

Rolfs A, Bonkovsky HL, Kohlroser JG, McNeal K, Sharma A, Berger UV, Hediger MA.

Am J Physiol Gastrointest Liver Physiol. 2002 Apr;282(4):G598-607.


The expression and regulation of the iron transport molecules hephaestin and IREG1: implications for the control of iron export from the small intestine.

Anderson GJ, Frazer DM, McKie AT, Wilkins SJ, Vulpe CD.

Cell Biochem Biophys. 2002;36(2-3):137-46. Review.


Iron supply determines apical/basolateral membrane distribution of intestinal iron transporters DMT1 and ferroportin 1.

Núñez MT, Tapia V, Rojas A, Aguirre P, Gómez F, Nualart F.

Am J Physiol Cell Physiol. 2010 Mar;298(3):C477-85. doi: 10.1152/ajpcell.00168.2009. Epub 2009 Dec 9.


An iron-regulated ferric reductase associated with the absorption of dietary iron.

McKie AT, Barrow D, Latunde-Dada GO, Rolfs A, Sager G, Mudaly E, Mudaly M, Richardson C, Barlow D, Bomford A, Peters TJ, Raja KB, Shirali S, Hediger MA, Farzaneh F, Simpson RJ.

Science. 2001 Mar 2;291(5509):1755-9. Epub 2001 Feb 1.


A novel mammalian iron-regulated protein involved in intracellular iron metabolism.

Abboud S, Haile DJ.

J Biol Chem. 2000 Jun 30;275(26):19906-12.


Mechanisms and regulation of intestinal iron absorption.

Morgan EH, Oates PS.

Blood Cells Mol Dis. 2002 Nov-Dec;29(3):384-99. Review.


Increased DMT1 but not IREG1 or HFE mRNA following iron depletion therapy in hereditary haemochromatosis.

Kelleher T, Ryan E, Barrett S, Sweeney M, Byrnes V, O'Keane C, Crowe J.

Gut. 2004 Aug;53(8):1174-9.


Duodenal expression of iron transport molecules in untreated haemochromatosis subjects.

Stuart KA, Anderson GJ, Frazer DM, Powell LW, McCullen M, Fletcher LM, Crawford DH.

Gut. 2003 Jul;52(7):953-9.


Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter.

Donovan A, Brownlie A, Zhou Y, Shepard J, Pratt SJ, Moynihan J, Paw BH, Drejer A, Barut B, Zapata A, Law TC, Brugnara C, Lux SE, Pinkus GS, Pinkus JL, Kingsley PD, Palis J, Fleming MD, Andrews NC, Zon LI.

Nature. 2000 Feb 17;403(6771):776-81.


Functional expression cloning and characterization of SFT, a stimulator of Fe transport.

Gutierrez JA, Yu J, Rivera S, Wessling-Resnick M.

J Cell Biol. 1997 Nov 17;139(4):895-905. Erratum in: J Cell Biol 1999 Oct 4;147(1):following 204.


Down-regulated in adenoma mediates apical Cl-/HCO3- exchange in rabbit, rat, and human duodenum.

Jacob P, Rossmann H, Lamprecht G, Kretz A, Neff C, Lin-Wu E, Gregor M, Groneberg DA, Kere J, Seidler U.

Gastroenterology. 2002 Mar;122(3):709-24.


Increased duodenal expression of divalent metal transporter 1 and iron-regulated gene 1 in cirrhosis.

Stuart KA, Anderson GJ, Frazer DM, Murphy TL, Powell LW, Fletcher LM, Crawford DH.

Hepatology. 2004 Feb;39(2):492-9.


Nramp2 expression is associated with pH-dependent iron uptake across the apical membrane of human intestinal Caco-2 cells.

Tandy S, Williams M, Leggett A, Lopez-Jimenez M, Dedes M, Ramesh B, Srai SK, Sharp P.

J Biol Chem. 2000 Jan 14;275(2):1023-9.


Expression of iron absorption genes in mouse large intestine.

Takeuchi K, Bjarnason I, Laftah AH, Latunde-Dada GO, Simpson RJ, McKie AT.

Scand J Gastroenterol. 2005 Feb;40(2):169-77.

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