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Items: 1 to 20 of 149


The role of CD154-CD40 versus CD28-B7 costimulatory pathways in regulating allogeneic Th1 and Th2 responses in vivo.

Kishimoto K, Dong VM, Issazadeh S, Fedoseyeva EV, Waaga AM, Yamada A, Sho M, Benichou G, Auchincloss H Jr, Grusby MJ, Khoury SJ, Sayegh MH.

J Clin Invest. 2000 Jul;106(1):63-72.


Role of STAT4 and STAT6 signaling in allograft rejection and CTLA4-Ig-mediated tolerance.

Zhou P, Szot GL, Guo Z, Kim O, He G, Wang J, Grusby MJ, Newell KA, Thistlethwaite JR, Bluestone JA, Alegre ML.

J Immunol. 2000 Nov 15;165(10):5580-7.


Differential regulation of Th1 and Th2 functions of NKT cells by CD28 and CD40 costimulatory pathways.

Hayakawa Y, Takeda K, Yagita H, Van Kaer L, Saiki I, Okumura K.

J Immunol. 2001 May 15;166(10):6012-8.


CD28-B7 blockade after alloantigenic challenge in vivo inhibits Th1 cytokines but spares Th2.

Sayegh MH, Akalin E, Hancock WW, Russell ME, Carpenter CB, Linsley PS, Turka LA.

J Exp Med. 1995 May 1;181(5):1869-74.


Analysis of the CD40 and CD28 pathways on alloimmune responses by CD4+ T cells in vivo.

Bingaman AW, Ha J, Durham MM, Waitze SY, Tucker-Burden C, Cowan SR, Pearson TC, Larsen CP.

Transplantation. 2001 Oct 15;72(7):1286-92.


Ligation of OX40 (CD134) regulates graft-versus-host disease (GVHD) and graft rejection in allogeneic bone marrow transplant recipients.

Blazar BR, Sharpe AH, Chen AI, Panoskaltsis-Mortari A, Lees C, Akiba H, Yagita H, Killeen N, Taylor PA.

Blood. 2003 May 1;101(9):3741-8. Epub 2003 Jan 9.


Aggressive skin allograft rejection in CD28-/- mice independent of the CD40/CD40L costimulatory pathway.

Ha J, Bingaman AW, Durham MM, Pearson TC, Larsen CP.

Transpl Immunol. 2001 Oct;9(1):13-7.


Costimulatory function and expression of CD40 ligand, CD80, and CD86 in vascularized murine cardiac allograft rejection.

Hancock WW, Sayegh MH, Zheng XG, Peach R, Linsley PS, Turka LA.

Proc Natl Acad Sci U S A. 1996 Nov 26;93(24):13967-72.


Modulation of costimulation by CD28 and CD154 alters the kinetics and cellular characteristics of corneal allograft rejection.

Ardjomand N, McAlister JC, Rogers NJ, Tan PH, George AJ, Larkin DF.

Invest Ophthalmol Vis Sci. 2003 Sep;44(9):3899-905.


Requirement for donor and recipient CD40 expression in cardiac allograft rejection: induction of Th1 responses and influence of donor-derived dendritic cells.

Nathan MJ, Mold JE, Wood SC, Csencsits K, Lu G, Eichwald EJ, Bishop DK.

J Immunol. 2004 Jun 1;172(11):6626-33.


Expression of B7 molecules in recipient, not donor, mice determines the survival of cardiac allografts.

Mandelbrot DA, Furukawa Y, McAdam AJ, Alexander SI, Libby P, Mitchell RN, Sharpe AH.

J Immunol. 1999 Oct 1;163(7):3753-7.


Th1 and Th2 mediate acute graft-versus-host disease, each with distinct end-organ targets.

Nikolic B, Lee S, Bronson RT, Grusby MJ, Sykes M.

J Clin Invest. 2000 May;105(9):1289-98.


Analysis of the role of negative T cell costimulatory pathways in CD4 and CD8 T cell-mediated alloimmune responses in vivo.

Ito T, Ueno T, Clarkson MR, Yuan X, Jurewicz MM, Yagita H, Azuma M, Sharpe AH, Auchincloss H Jr, Sayegh MH, Najafian N.

J Immunol. 2005 Jun 1;174(11):6648-56.


CD28-B7 T cell costimulatory blockade by CTLA4Ig in sensitized rat recipients: induction of transplantation tolerance in association with depressed cell-mediated and humoral immune responses.

Onodera K, Chandraker A, Schaub M, Stadlbauer TH, Korom S, Peach R, Linsley PS, Sayegh MH, Kupiec-Weglinski JW.

J Immunol. 1997 Aug 15;159(4):1711-7.


CTLA4 signals are required to optimally induce allograft tolerance with combined donor-specific transfusion and anti-CD154 monoclonal antibody treatment.

Zheng XX, Markees TG, Hancock WW, Li Y, Greiner DL, Li XC, Mordes JP, Sayegh MH, Rossini AA, Strom TB.

J Immunol. 1999 Apr 15;162(8):4983-90.


The roles of CD28 and CD40 ligand in T cell activation and tolerance.

Howland KC, Ausubel LJ, London CA, Abbas AK.

J Immunol. 2000 May 1;164(9):4465-70.


Immature syngeneic dendritic cells potentiate tolerance to pancreatic islet allografts depleted of donor dendritic cells in microgravity culture condition.

Stepkowski SM, Phan T, Zhang H, Bilinski S, Kloc M, Qi Y, Katz SM, Rutzky LP.

Transplantation. 2006 Dec 27;82(12):1756-63.


CD70 signaling is critical for CD28-independent CD8+ T cell-mediated alloimmune responses in vivo.

Yamada A, Salama AD, Sho M, Najafian N, Ito T, Forman JP, Kewalramani R, Sandner S, Harada H, Clarkson MR, Mandelbrot DA, Sharpe AH, Oshima H, Yagita H, Chalasani G, Lakkis FG, Auchincloss H Jr, Sayegh MH.

J Immunol. 2005 Feb 1;174(3):1357-64.

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