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Prohibitins act as a membrane-bound chaperone for the stabilization of mitochondrial proteins.

Nijtmans LG, de Jong L, Artal Sanz M, Coates PJ, Berden JA, Back JW, Muijsers AO, van der Spek H, Grivell LA.

EMBO J. 2000 Jun 1;19(11):2444-51.


The mitochondrial PHB complex: roles in mitochondrial respiratory complex assembly, ageing and degenerative disease.

Nijtmans LG, Artal SM, Grivell LA, Coates PJ.

Cell Mol Life Sci. 2002 Jan;59(1):143-55. Review.


The mitochondrial prohibitin complex is essential for embryonic viability and germline function in Caenorhabditis elegans.

Artal-Sanz M, Tsang WY, Willems EM, Grivell LA, Lemire BD, van der Spek H, Nijtmans LG.

J Biol Chem. 2003 Aug 22;278(34):32091-9. Epub 2003 Jun 6. Erratum in: J Biol Chem. 2003 Oct 10;278(41):40416. Sanz Marta Artal [corrected to Artal-Sanz Marta].


Prohibitins regulate membrane protein degradation by the m-AAA protease in mitochondria.

Steglich G, Neupert W, Langer T.

Mol Cell Biol. 1999 May;19(5):3435-42.


The shortened replicative life span of prohibitin mutants of yeast appears to be due to defective mitochondrial segregation in old mother cells.

Piper PW, Jones GW, Bringloe D, Harris N, MacLean M, Mollapour M.

Aging Cell. 2002 Dec;1(2):149-57.


Prohibitin and mitochondrial biology.

Artal-Sanz M, Tavernarakis N.

Trends Endocrinol Metab. 2009 Oct;20(8):394-401. doi: 10.1016/j.tem.2009.04.004. Epub 2009 Sep 3. Review.


Formation of membrane-bound ring complexes by prohibitins in mitochondria.

Tatsuta T, Model K, Langer T.

Mol Biol Cell. 2005 Jan;16(1):248-59. Epub 2004 Nov 3.


Prohibitins and Ras2 protein cooperate in the maintenance of mitochondrial function during yeast aging.

Kirchman PA, Miceli MV, West RL, Jiang JC, Kim S, Jazwinski SM.

Acta Biochim Pol. 2003;50(4):1039-56.


Identification of mammalian TOM22 as a subunit of the preprotein translocase of the mitochondrial outer membrane.

Saeki K, Suzuki H, Tsuneoka M, Maeda M, Iwamoto R, Hasuwa H, Shida S, Takahashi T, Sakaguchi M, Endo T, Miura Y, Mekada E, Mihara K.

J Biol Chem. 2000 Oct 13;275(41):31996-2002.


The prohibitin family of mitochondrial proteins regulate replicative lifespan.

Coates PJ, Jamieson DJ, Smart K, Prescott AR, Hall PA.

Curr Biol. 1997 Aug 1;7(8):607-10.


Specific targeting of ISP6 to mitochondria is mediated by sequences other than its amino terminus.

Cao W, Douglas MG.

Biochem Biophys Res Commun. 1996 Jul 16;224(2):457-61.


Prohibitins and the functional compartmentalization of mitochondrial membranes.

Osman C, Merkwirth C, Langer T.

J Cell Sci. 2009 Nov 1;122(Pt 21):3823-30. doi: 10.1242/jcs.037655. Review.


Molecular chaperones as essential mediators of mitochondrial biogenesis.

Voos W, Röttgers K.

Biochim Biophys Acta. 2002 Sep 2;1592(1):51-62. Review.


The two mitochondrial heat shock proteins 70, Ssc1 and Ssq1, compete for the cochaperone Mge1.

Schmidt S, Strub A, Röttgers K, Zufall N, Voos W.

J Mol Biol. 2001 Oct 12;313(1):13-26.


Prohibitin function within mitochondria: essential roles for cell proliferation and cristae morphogenesis.

Merkwirth C, Langer T.

Biochim Biophys Acta. 2009 Jan;1793(1):27-32. doi: 10.1016/j.bbamcr.2008.05.013. Epub 2008 Jun 17. Review.


Yeast prion [PSI+] lowers the levels of mitochondrial prohibitins.

Sikora J, Towpik J, Graczyk D, Kistowski M, Rubel T, Poznanski J, Langridge J, Hughes C, Dadlez M, Boguta M.

Biochim Biophys Acta. 2009 Nov;1793(11):1703-9. doi: 10.1016/j.bbamcr.2009.08.003. Epub 2009 Aug 18.


The PHB1/2 phosphocomplex is required for mitochondrial homeostasis and survival of human T cells.

Ross JA, Nagy ZS, Kirken RA.

J Biol Chem. 2008 Feb 22;283(8):4699-713. Epub 2007 Dec 17.

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