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Items: 1 to 20 of 195

1.

Functional interaction between the Werner Syndrome protein and DNA polymerase delta.

Kamath-Loeb AS, Johansson E, Burgers PM, Loeb LA.

Proc Natl Acad Sci U S A. 2000 Apr 25;97(9):4603-8.

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3.

Characterisation of the interaction between WRN, the helicase/exonuclease defective in progeroid Werner's syndrome, and an essential replication factor, PCNA.

Rodríguez-López AM, Jackson DA, Nehlin JO, Iborra F, Warren AV, Cox LS.

Mech Ageing Dev. 2003 Feb;124(2):167-74.

PMID:
12633936
4.

The Werner syndrome protein stimulates DNA polymerase beta strand displacement synthesis via its helicase activity.

Harrigan JA, Opresko PL, von Kobbe C, Kedar PS, Prasad R, Wilson SH, Bohr VA.

J Biol Chem. 2003 Jun 20;278(25):22686-95. Epub 2003 Mar 27.

5.

Werner protein recruits DNA polymerase delta to the nucleolus.

Szekely AM, Chen YH, Zhang C, Oshima J, Weissman SM.

Proc Natl Acad Sci U S A. 2000 Oct 10;97(21):11365-70.

6.

Requirements for the nucleolytic processing of DNA ends by the Werner syndrome protein-Ku70/80 complex.

Li B, Comai L.

J Biol Chem. 2001 Mar 30;276(13):9896-902. Epub 2001 Jan 4.

7.

The N-terminal domain of the large subunit of human replication protein A binds to Werner syndrome protein and stimulates helicase activity.

Shen JC, Lao Y, Kamath-Loeb A, Wold MS, Loeb LA.

Mech Ageing Dev. 2003 Aug-Sep;124(8-9):921-30.

PMID:
14499497
8.

Nuclear DNA helicase II (RNA helicase A) interacts with Werner syndrome helicase and stimulates its exonuclease activity.

Friedemann J, Grosse F, Zhang S.

J Biol Chem. 2005 Sep 2;280(35):31303-13. Epub 2005 Jul 1.

9.

p53 Modulates the exonuclease activity of Werner syndrome protein.

Brosh RM Jr, Karmakar P, Sommers JA, Yang Q, Wang XW, Spillare EA, Harris CC, Bohr VA.

J Biol Chem. 2001 Sep 14;276(37):35093-102. Epub 2001 Jun 26.

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11.

The Werner syndrome exonuclease facilitates DNA degradation and high fidelity DNA polymerization by human DNA polymerase δ.

Kamath-Loeb AS, Shen JC, Schmitt MW, Loeb LA.

J Biol Chem. 2012 Apr 6;287(15):12480-90. doi: 10.1074/jbc.M111.332577. Epub 2012 Feb 17.

12.

Unwinding the molecular basis of the Werner syndrome.

Shen J, Loeb LA.

Mech Ageing Dev. 2001 Jul 15;122(9):921-44. Review.

PMID:
11348659
13.

Werner syndrome protein interacts with human flap endonuclease 1 and stimulates its cleavage activity.

Brosh RM Jr, von Kobbe C, Sommers JA, Karmakar P, Opresko PL, Piotrowski J, Dianova I, Dianov GL, Bohr VA.

EMBO J. 2001 Oct 15;20(20):5791-801.

14.

Enzymatic mechanism of the WRN helicase/nuclease.

Brosh RM Jr, Opresko PL, Bohr VA.

Methods Enzymol. 2006;409:52-85.

PMID:
16793395
15.

WRN, the protein deficient in Werner syndrome, plays a critical structural role in optimizing DNA repair.

Chen L, Huang S, Lee L, Davalos A, Schiestl RH, Campisi J, Oshima J.

Aging Cell. 2003 Aug;2(4):191-9.

PMID:
12934712
16.

Central role for the Werner syndrome protein/poly(ADP-ribose) polymerase 1 complex in the poly(ADP-ribosyl)ation pathway after DNA damage.

von Kobbe C, Harrigan JA, May A, Opresko PL, Dawut L, Cheng WH, Bohr VA.

Mol Cell Biol. 2003 Dec;23(23):8601-13.

17.

Coordinate action of the helicase and 3' to 5' exonuclease of Werner syndrome protein.

Opresko PL, Laine JP, Brosh RM Jr, Seidman MM, Bohr VA.

J Biol Chem. 2001 Nov 30;276(48):44677-87. Epub 2001 Sep 25.

18.

The Werner syndrome gene: the molecular basis of RecQ helicase-deficiency diseases.

Shen JC, Loeb LA.

Trends Genet. 2000 May;16(5):213-20. Review.

PMID:
10782115
19.

Identification and biochemical characterization of a Werner's syndrome protein complex with Ku70/80 and poly(ADP-ribose) polymerase-1.

Li B, Navarro S, Kasahara N, Comai L.

J Biol Chem. 2004 Apr 2;279(14):13659-67. Epub 2004 Jan 20.

20.

The Werner syndrome protein is involved in RNA polymerase II transcription.

Balajee AS, Machwe A, May A, Gray MD, Oshima J, Martin GM, Nehlin JO, Brosh R, Orren DK, Bohr VA.

Mol Biol Cell. 1999 Aug;10(8):2655-68.

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