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Items: 1 to 20 of 87

1.

Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo.

Hoffmeyer S, Burk O, von Richter O, Arnold HP, Brockmöller J, Johne A, Cascorbi I, Gerloff T, Roots I, Eichelbaum M, Brinkmann U.

Proc Natl Acad Sci U S A. 2000 Mar 28;97(7):3473-8.

2.

Expression of P-glycoprotein in human placenta: relation to genetic polymorphism of the multidrug resistance (MDR)-1 gene.

Tanabe M, Ieiri I, Nagata N, Inoue K, Ito S, Kanamori Y, Takahashi M, Kurata Y, Kigawa J, Higuchi S, Terakawa N, Otsubo K.

J Pharmacol Exp Ther. 2001 Jun;297(3):1137-43.

3.

Human intestinal P-glycoprotein activity estimated by the model substrate digoxin.

Larsen UL, Hyldahl Olesen L, Guldborg Nyvold C, Eriksen J, Jakobsen P, Østergaard M, Autrup H, Andersen V.

Scand J Clin Lab Invest. 2007;67(2):123-34.

PMID:
17365992
4.

C3435T polymorphism in the MDR1 gene affects the enterocyte expression level of CYP3A4 rather than Pgp in recipients of living-donor liver transplantation.

Goto M, Masuda S, Saito H, Uemoto S, Kiuchi T, Tanaka K, Inui K.

Pharmacogenetics. 2002 Aug;12(6):451-7.

PMID:
12172213
6.

The C3435T mutation in the human MDR1 gene is associated with altered efflux of the P-glycoprotein substrate rhodamine 123 from CD56+ natural killer cells.

Hitzl M, Drescher S, van der Kuip H, Schäffeler E, Fischer J, Schwab M, Eichelbaum M, Fromm MF.

Pharmacogenetics. 2001 Jun;11(4):293-8.

PMID:
11434506
7.

Single step PCR for detection of allelic variation of MDR1 gene (P-glycoprotein) among three ethnic groups in Malaysia.

Teh LK, Lee WL, Amir J, Salleh MZ, Ismail R.

J Clin Pharm Ther. 2007 Jun;32(3):313-9. Erratum in: J Clin Pharm Ther. 2007 Aug;32(4):413.

PMID:
17489883
8.
9.

MDR1 pharmacogenetics: frequency of the C3435T mutation in exon 26 is significantly influenced by ethnicity.

Ameyaw MM, Regateiro F, Li T, Liu X, Tariq M, Mobarek A, Thornton N, Folayan GO, Githang'a J, Indalo A, Ofori-Adjei D, Price-Evans DA, McLeod HL.

Pharmacogenetics. 2001 Apr;11(3):217-21.

PMID:
11337937
10.
11.

Polymorphism C3435T of the MDR-1 gene predicts response to preoperative chemotherapy in locally advanced breast cancer.

Kafka A, Sauer G, Jaeger C, Grundmann R, Kreienberg R, Zeillinger R, Deissler H.

Int J Oncol. 2003 May;22(5):1117-21.

PMID:
12684679
12.

Effect of the mutation (C3435T) at exon 26 of the MDR1 gene on expression level of MDR1 messenger ribonucleic acid in duodenal enterocytes of healthy Japanese subjects.

Nakamura T, Sakaeda T, Horinouchi M, Tamura T, Aoyama N, Shirakawa T, Matsuo M, Kasuga M, Okumura K.

Clin Pharmacol Ther. 2002 Apr;71(4):297-303.

PMID:
11956513
13.

P-glycoprotein polymorphism in hypo- and hyper-thyroidism patients.

Turgut G, Baştemir M, Turgut S, Akin F, Kursunluoglu R, Kaptanoğlu B.

Mol Biol Rep. 2008 Dec;35(4):693-8. Epub 2007 Sep 21.

PMID:
17891478
14.

Relationship between the C3435T and G2677T(A) polymorphisms in the ABCB1 gene and P-glycoprotein expression in human liver.

Owen A, Goldring C, Morgan P, Chadwick D, Park BK, Pirmohamed M.

Br J Clin Pharmacol. 2005 Mar;59(3):365-70.

15.

Single nucleotide polymorphisms in the multidrug resistance gene 1 (ABCB1): effects on its expression and clinicopathological characteristics in breast cancer patients.

Vaclavikova R, Nordgard SH, Alnaes GI, Hubackova M, Kubala E, Kodet R, Mrhalova M, Novotny J, Gut I, Kristensen VN, Soucek P.

Pharmacogenet Genomics. 2008 Mar;18(3):263-73. doi: 10.1097/FPC.0b013e3282f60a91.

PMID:
18300948
16.

The effects of the human MDR1 genotype on the expression of duodenal P-glycoprotein and disposition of the probe drug talinolol.

Siegmund W, Ludwig K, Giessmann T, Dazert P, Schroeder E, Sperker B, Warzok R, Kroemer HK, Cascorbi I.

Clin Pharmacol Ther. 2002 Nov;72(5):572-83.

PMID:
12426521
17.

mdr-1 single nucleotide polymorphisms in ovarian cancer tissue: G2677T/A correlates with response to paclitaxel chemotherapy.

Gréen H, Söderkvist P, Rosenberg P, Horvath G, Peterson C.

Clin Cancer Res. 2006 Feb 1;12(3 Pt 1):854-9.

18.

Variable expression of P-glycoprotein in the human placenta and its association with mutations of the multidrug resistance 1 gene (MDR1, ABCB1).

Hitzl M, Schaeffeler E, Hocher B, Slowinski T, Halle H, Eichelbaum M, Kaufmann P, Fritz P, Fromm MF, Schwab M.

Pharmacogenetics. 2004 May;14(5):309-18.

PMID:
15115917
19.

Lack of association between the C3435T polymorphism in the human multidrug resistance (MDR1) gene and response to antiepileptic drug treatment.

Sills GJ, Mohanraj R, Butler E, McCrindle S, Collier L, Wilson EA, Brodie MJ.

Epilepsia. 2005 May;46(5):643-7.

20.

MDR1 C3435T polymorphism in patients with breast cancer.

Turgut S, Yaren A, Kursunluoglu R, Turgut G.

Arch Med Res. 2007 Jul;38(5):539-44. Epub 2007 Apr 26.

PMID:
17560460
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