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Items: 1 to 20 of 106

1.

FADD/MORT1 regulates the pre-TCR checkpoint and can function as a tumour suppressor.

Newton K, Harris AW, Strasser A.

EMBO J. 2000 Mar 1;19(5):931-41.

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Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort1.

Zhang J, Cado D, Chen A, Kabra NH, Winoto A.

Nature. 1998 Mar 19;392(6673):296-300.

PMID:
9521326
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The requirements for Fas-associated death domain signaling in mature T cell activation and survival.

Beisner DR, Chu IH, Arechiga AF, Hedrick SM, Walsh CM.

J Immunol. 2003 Jul 1;171(1):247-56.

6.

Essential role of Rap signal in pre-TCR-mediated beta-selection checkpoint in alphabeta T-cell development.

Kometani K, Moriyama M, Nakashima Y, Katayama Y, Wang SF, Yamasaki S, Saito T, Hattori M, Minato N.

Blood. 2008 Dec 1;112(12):4565-73. doi: 10.1182/blood-2008-06-164517. Epub 2008 Sep 18.

7.

T cell-specific FADD-deficient mice: FADD is required for early T cell development.

Kabra NH, Kang C, Hsing LC, Zhang J, Winoto A.

Proc Natl Acad Sci U S A. 2001 May 22;98(11):6307-12. Epub 2001 May 15.

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Effects of a dominant interfering mutant of FADD on signal transduction in activated T cells.

Newton K, Kurts C, Harris AW, Strasser A.

Curr Biol. 2001 Feb 20;11(4):273-6.

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13.

Opposite ability of pre-TCR and alpha beta TCR to induce apoptosis.

Steff AM, Trop S, Maira M, Drouin J, Hugo P.

J Immunol. 2001 Apr 15;166(8):5044-50.

14.

FADD and the NF-kappaB family member Bcl-3 regulate complementary pathways to control T-cell survival and proliferation.

Rangelova S, Kirschnek S, Strasser A, Häcker G.

Immunology. 2008 Dec;125(4):549-57. doi: 10.1111/j.1365-2567.2008.02869.x. Epub 2008 Jun 13.

15.

Fas-associated death domain (FADD) is a negative regulator of T-cell receptor-mediated necroptosis.

Osborn SL, Diehl G, Han SJ, Xue L, Kurd N, Hsieh K, Cado D, Robey EA, Winoto A.

Proc Natl Acad Sci U S A. 2010 Jul 20;107(29):13034-9. doi: 10.1073/pnas.1005997107. Epub 2010 Jul 6.

16.

Premature TCR alpha beta expression and signaling in early thymocytes impair thymocyte expansion and partially block their development.

Lacorazza HD, Tucek-Szabo C, Vasović LV, Remus K, Nikolich-Zugich J.

J Immunol. 2001 Mar 1;166(5):3184-93.

17.

Precursor thymocyte proliferation and differentiation are controlled by signals unrelated to the pre-TCR.

Petrie HT, Tourigny M, Burtrum DB, Livak F.

J Immunol. 2000 Sep 15;165(6):3094-8.

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The requirement for pre-TCR during thymic differentiation enforces a developmental pause that is essential for V-DJβ rearrangement.

Hathcock KS, Farrington L, Ivanova I, Livak F, Selimyan R, Sen R, Williams J, Tai X, Hodes RJ.

PLoS One. 2011;6(6):e20639. doi: 10.1371/journal.pone.0020639. Epub 2011 Jun 3.

20.

Regulation of thymocyte differentiation: pre-TCR signals and beta-selection.

Michie AM, Zúñiga-Pflücker JC.

Semin Immunol. 2002 Oct;14(5):311-23. Review.

PMID:
12220932
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