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Results: 1 to 20 of 312

1.

Substitution of leucine 28 with histidine in the Escherichia coli transcription factor FNR results in increased stability of the [4Fe-4S](2+) cluster to oxygen.

Bates DM, Popescu CV, Khoroshilova N, Vogt K, Beinert H, Münck E, Kiley PJ.

J Biol Chem. 2000 Mar 3;275(9):6234-40.

PMID:
10692418
[PubMed - indexed for MEDLINE]
Free Article
2.

Oxygen sensing by the global regulator, FNR: the role of the iron-sulfur cluster.

Kiley PJ, Beinert H.

FEMS Microbiol Rev. 1998 Dec;22(5):341-52. Review.

PMID:
9990723
[PubMed - indexed for MEDLINE]
Free Article
3.

Iron-sulfur cluster disassembly in the FNR protein of Escherichia coli by O2: [4Fe-4S] to [2Fe-2S] conversion with loss of biological activity.

Khoroshilova N, Popescu C, Münck E, Beinert H, Kiley PJ.

Proc Natl Acad Sci U S A. 1997 Jun 10;94(12):6087-92.

PMID:
9177174
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

DNA binding and dimerization of the Fe-S-containing FNR protein from Escherichia coli are regulated by oxygen.

Lazazzera BA, Beinert H, Khoroshilova N, Kennedy MC, Kiley PJ.

J Biol Chem. 1996 Feb 2;271(5):2762-8.

PMID:
8576252
[PubMed - indexed for MEDLINE]
Free Article
5.

Superoxide destroys the [2Fe-2S]2+ cluster of FNR from Escherichia coli.

Sutton VR, Stubna A, Patschkowski T, Münck E, Beinert H, Kiley PJ.

Biochemistry. 2004 Jan 27;43(3):791-8.

PMID:
14730984
[PubMed - indexed for MEDLINE]
6.

Role of glutathione in the formation of the active form of the oxygen sensor FNR ([4Fe-4S].FNR) and in the control of FNR function.

Tran QH, Arras T, Becker S, Holighaus G, Ohlberger G, Unden G.

Eur J Biochem. 2000 Aug;267(15):4817-24.

PMID:
10903516
[PubMed - indexed for MEDLINE]
Free Article
7.

Regulation of FNR dimerization by subunit charge repulsion.

Moore LJ, Mettert EL, Kiley PJ.

J Biol Chem. 2006 Nov 3;281(44):33268-75. Epub 2006 Sep 7.

PMID:
16959764
[PubMed - indexed for MEDLINE]
Free Article
8.

ClpXP-dependent proteolysis of FNR upon loss of its O2-sensing [4Fe-4S] cluster.

Mettert EL, Kiley PJ.

J Mol Biol. 2005 Nov 25;354(2):220-32. Epub 2005 Oct 7.

PMID:
16243354
[PubMed - indexed for MEDLINE]
9.

Reactions of nitric oxide and oxygen with the regulator of fumarate and nitrate reduction, a global transcriptional regulator, during anaerobic growth of Escherichia coli.

Crack JC, Le Brun NE, Thomson AJ, Green J, Jervis AJ.

Methods Enzymol. 2008;437:191-209. doi: 10.1016/S0076-6879(07)37011-0. Review.

PMID:
18433630
[PubMed - indexed for MEDLINE]
10.

Mössbauer spectroscopy as a tool for the study of activation/inactivation of the transcription regulator FNR in whole cells of Escherichia coli.

Popescu CV, Bates DM, Beinert H, Münck E, Kiley PJ.

Proc Natl Acad Sci U S A. 1998 Nov 10;95(23):13431-5.

PMID:
9811817
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Reconstitution of the [4Fe-4S] cluster in FNR and demonstration of the aerobic-anaerobic transcription switch in vitro.

Green J, Bennett B, Jordan P, Ralph ET, Thomson AJ, Guest JR.

Biochem J. 1996 Jun 15;316 ( Pt 3):887-92.

PMID:
8670167
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Bacillus subtilis Fnr senses oxygen via a [4Fe-4S] cluster coordinated by three cysteine residues without change in the oligomeric state.

Reents H, Gruner I, Harmening U, Böttger LH, Layer G, Heathcote P, Trautwein AX, Jahn D, Härtig E.

Mol Microbiol. 2006 Jun;60(6):1432-45.

PMID:
16796679
[PubMed - indexed for MEDLINE]
13.

The O2 sensitivity of the transcription factor FNR is controlled by Ser24 modulating the kinetics of [4Fe-4S] to [2Fe-2S] conversion.

Jervis AJ, Crack JC, White G, Artymiuk PJ, Cheesman MR, Thomson AJ, Le Brun NE, Green J.

Proc Natl Acad Sci U S A. 2009 Mar 24;106(12):4659-64. doi: 10.1073/pnas.0804943106. Epub 2009 Mar 4.

PMID:
19261852
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Reversible cycling between cysteine persulfide-ligated [2Fe-2S] and cysteine-ligated [4Fe-4S] clusters in the FNR regulatory protein.

Zhang B, Crack JC, Subramanian S, Green J, Thomson AJ, Le Brun NE, Johnson MK.

Proc Natl Acad Sci U S A. 2012 Sep 25;109(39):15734-9. Epub 2012 Sep 10.

PMID:
23019358
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Kinetic analysis of the oxidative conversion of the [4Fe-4S]2+ cluster of FNR to a [2Fe-2S]2+ Cluster.

Sutton VR, Mettert EL, Beinert H, Kiley PJ.

J Bacteriol. 2004 Dec;186(23):8018-25.

PMID:
15547274
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

FNR is a direct oxygen sensor having a biphasic response curve.

Jordan PA, Thomson AJ, Ralph ET, Guest JR, Green J.

FEBS Lett. 1997 Oct 27;416(3):349-52.

PMID:
9373183
[PubMed - indexed for MEDLINE]
Free Article
17.

Contributions of [4Fe-4S]-FNR and integration host factor to fnr transcriptional regulation.

Mettert EL, Kiley PJ.

J Bacteriol. 2007 Apr;189(8):3036-43. Epub 2007 Feb 9.

PMID:
17293415
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Properties and significance of apoFNR as a second form of air-inactivated [4Fe-4S].FNR of Escherichia coli.

Achebach S, Selmer T, Unden G.

FEBS J. 2005 Aug;272(16):4260-9.

PMID:
16098206
[PubMed - indexed for MEDLINE]
Free Article
19.

The impact of O(2) on the Fe-S cluster biogenesis requirements of Escherichia coli FNR.

Mettert EL, Outten FW, Wanta B, Kiley PJ.

J Mol Biol. 2008 Dec 26;384(4):798-811. doi: 10.1016/j.jmb.2008.09.080. Epub 2008 Oct 10.

PMID:
18938178
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Evidence that the Streptomyces developmental protein WhiD, a member of the WhiB family, binds a [4Fe-4S] cluster.

Jakimowicz P, Cheesman MR, Bishai WR, Chater KF, Thomson AJ, Buttner MJ.

J Biol Chem. 2005 Mar 4;280(9):8309-15. Epub 2004 Dec 21.

PMID:
15615709
[PubMed - indexed for MEDLINE]
Free Article
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