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10634385,11443192,9024260,10372723,9745404,9425400,10199772,12030918,9703380,15126555,8949573,9467533,10592440,9141536,11836328,11836333,15879357,18464752,19240251,9626127,15817913,11443205,10902783,9768681,10037246,8989263,11238491,11322505,11994347,19351723,9851759,11443159,10323388,19458139,11158034,16390864,15237710,12161519,9141538,11739462,8496311,8768842,15963058,12370860,10720049,10629166,7593428,10566659,11397840,10946861,15240578,9329386,7962302,10372687,16926252,10720081,10084566,7515387,1379256,11095453,11248742,12238241,11158008,16990657,12887288,11232010,10931086,9368506,16862465,9100598,15634714,8768841,12050264,9920097,9435412,9253336,9623518,11134132,16821203,11443216,11030292,8550799,16189179,11994325,9589674,8675561,19581656,11527085,17405836,11443201,10193871,9666868,11407654,15270408,10770197,11227726,9876338,8875138,16821205,10484590,23485864,12240900,10601963,11434664,14616884,16150898,8921821,21047921,19696160,24114435,1915110,11849250,22990092,11861495,1721565,14960017,10913042,9368834,24899762,19351731,7586594,9557822,10468900,10209563,10444419,9751243,22416077,14551231,21467302,11314741,10870025,11263473,7688671,10435851,28285644,10728152,10411234,11476767,19858315,10698044,19845749,7641401,10946886,15713362,10582552,15562401,15198293,12932748,11888836,18984660,12641632,19636643,10090131,9390009,7535669,12580940,9732206,18703567,15356066,18728158,18593763,7542982,7525826,9988395,9666874,14669827,15579794,31361307,1909610,28830317,9238854,11936462,7691702,18647804,9291202,1715381,8548943,14610296,9597048,26228064,9930632,14594172,17697791,18073313,8762728,10233027,1719338,9640414,9820615,9085516,12653875,9710103,7889617,9041873,19568604,11531924,7955462,11158013,11248743,12044524,17550998,11200934,17609397,9585386,10990135,9867079,10591235,10690937,9364338,18221393,9700676,11171604,20926525,8742123,20203424,28460598,1720806,21932585,21795635,20943777,15811926,12519870,25381601,17662149,15613418,8300049,10619979,11836282,9173938,12841541,11254469,23785020,11089529,8810735,11213276,11453955,7683247,9207127,9437227,24340285,15356089,9063653,9361690,15844470,30032193,12670836,33125080,17689128,20953065,1695151,11902289,19051037,9373883,12865482,26894743,12580941,10985757,9364353,15728217,22621959,20299490,9267949,20190159,11967190,1723835,21613353,11322501,27693042,31776295,10990147,9806317,8793891,1707435,15879692,10469012,7506819,9565931,18540253,7523649,7506288,8884537,9848301,12109625,25210881,1453131,8853449,11701711,19088159,7594222,10725773,11021768,7521246,22960989,8742122,20583540,22456022,17537842,12002412,9722182,7545763,10831578,17709895,24983853,26732027,12800538,18445667,10984320,1709896,12844340,8370685,1311401,10475152,18432585,12376329,17634080,1958517,9437228,30547374,17003023,24927347,26864960,7545263,11126270,7538403,1376980,9046989,12381331,11004017,9510448,9758441,1693323,11502785,10803476,9844957,10442574,8969286,12714012,21706151,29208686,14670810,19470623,31022718,29278514,2138277,8676044,1786697,2911937,18482854,23197045,2754367,2723911,9449031,28428227,33125822,21502796,18537700,15754728,12792153,19470834,2023299,12505887,34118743,7716722,9506860,17897098,10662706,2110412,25374440,9928604,9116911,10770194,24291224,19318223,23058019,31527400,14510911,30543929,19470622,9688993,7689089,19755477,14964431,9064277,10025745,2609899,8742127,19878147,11310349,29280739,10392348,19386527,29989677,10938244,27716276,7577071,7543111,17644863,28529277,9302394,11726733,8557135,9227458,26843472,12393957,29045090,11499736,23179244,34220703,9138969,14515015,9173963,21177759,10780951,7508976,22029850,28796357,28477733,9224438,32861700,7507879,30840065,16840657,17387582,24569590,1752057,16353427,29124746,11318766,11419677,8409184,14732199,15223841,8957747,32102608,10997644,12889843,9449030,11334967,8531260,2591131,9625055,12450625,9234296,14686753,8859140,26386685,1376285,26443692,8887306,33021069,30901100,8001865,25375982,25461385,24424061,24236134,33378445,21797891,9076348,2728860,20176597,9116314,10584673,18057380,18611978,35474467,10993591,12428995,11139770,1698701,10453940,11004016,15129806,11392377,36493869,24096994,7828430,10083899,12914751,19602556,11054648,8315259,16022754,31939487,7586621,9364249,9207592,19942987,8968266,9925180,27605408,34032853,11923043,17986822,11174833,18456366,10644927,9520907,19907099,8968265,31967977,10984310,25179796,9124538,12785467,2118602,7608381,25633069,12127047,9502186,10968476,18797598,24161750,10596723,12002407,18334589,8772569,11158932,12008749,22363612,19492582,18427424,11259859,1730338,28135645,18362505,10912519,2245967,21531600,20940674,2465307,22472562,10997619,7595601,9639222,9500574,21291516,32973684,21113585,8797634,12077495,2462321,10821137,19837911,32739295,16809927,9506861,35432211,18053120,8797616,12903889,11451284,2391594,19861588,12952376,30359693,26214107,17311540,11434520,29383334,7614245,27639100,35421826,19491298,12053088,11166358,10973769,2352477,10987675,19783851,7952159,12907842,37033129,9792385,10601959,2299282,1584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795 results

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A paradoxical gender dissociation within the growth hormone/insulin-like growth factor I axis during protracted critical illness.

Van den Berghe G, Baxter RC, Weekers F, Wouters P, Bowers CY, Veldhuis JD. Van den Berghe G, et al. J Clin Endocrinol Metab. 2000 Jan;85(1):183-92. doi: 10.1210/jcem.85.1.6316. J Clin Endocrinol Metab. 2000. PMID: 10634385 Clinical Trial.

Five-day pulsatile gonadotropin-releasing hormone administration unveils combined hypothalamic-pituitary-gonadal defects underlying profound hypoandrogenism in men with prolonged critical illness.

van den Berghe G, Weekers F, Baxter RC, Wouters P, Iranmanesh A, Bouillon R, Veldhuis JD. van den Berghe G, et al. J Clin Endocrinol Metab. 2001 Jul;86(7):3217-26. doi: 10.1210/jcem.86.7.7680. J Clin Endocrinol Metab. 2001. PMID: 11443192 Clinical Trial.

The somatotropic axis in critical illness: effect of continuous growth hormone (GH)-releasing hormone and GH-releasing peptide-2 infusion.

Van den Berghe G, de Zegher F, Veldhuis JD, Wouters P, Awouters M, Verbruggen W, Schetz M, Verwaest C, Lauwers P, Bouillon R, Bowers CY. Van den Berghe G, et al. J Clin Endocrinol Metab. 1997 Feb;82(2):590-9. doi: 10.1210/jcem.82.2.3736. J Clin Endocrinol Metab. 1997. PMID: 9024260 Clinical Trial.

Tripartite neuroendocrine activation of the human growth hormone (GH) axis in women by continuous 24-hour GH-releasing peptide infusion: pulsatile, entropic, and nyctohemeral mechanisms.

Shah N, Evans WS, Bowers CY, Veldhuis JD. Shah N, et al. J Clin Endocrinol Metab. 1999 Jun;84(6):2140-50. doi: 10.1210/jcem.84.6.5687. J Clin Endocrinol Metab. 1999. PMID: 10372723 Clinical Trial.

Leptin levels in protracted critical illness: effects of growth hormone-secretagogues and thyrotropin-releasing hormone.

Van den Berghe G, Wouters P, Carlsson L, Baxter RC, Bouillon R, Bowers CY. Van den Berghe G, et al. J Clin Endocrinol Metab. 1998 Sep;83(9):3062-70. doi: 10.1210/jcem.83.9.5120. J Clin Endocrinol Metab. 1998. PMID: 9745404 Clinical Trial.

Thyrotrophin and prolactin release in prolonged critical illness: dynamics of spontaneous secretion and effects of growth hormone-secretagogues.

Van den Berghe G, de Zegher F, Veldhuis JD, Wouters P, Gouwy S, Stockman W, Weekers F, Schetz M, Lauwers P, Bouillon R, Bowers CY. Van den Berghe G, et al. Clin Endocrinol (Oxf). 1997 Nov;47(5):599-612. doi: 10.1046/j.1365-2265.1997.3371118.x. Clin Endocrinol (Oxf). 1997. PMID: 9425400 Clinical Trial.

Reactivation of pituitary hormone release and metabolic improvement by infusion of growth hormone-releasing peptide and thyrotropin-releasing hormone in patients with protracted critical illness.

Van den Berghe G, Wouters P, Weekers F, Mohan S, Baxter RC, Veldhuis JD, Bowers CY, Bouillon R. Van den Berghe G, et al. J Clin Endocrinol Metab. 1999 Apr;84(4):1311-23. doi: 10.1210/jcem.84.4.5636. J Clin Endocrinol Metab. 1999. PMID: 10199772 Clinical Trial.

The combined administration of GH-releasing peptide-2 (GHRP-2), TRH and GnRH to men with prolonged critical illness evokes superior endocrine and metabolic effects compared to treatment with GHRP-2 alone.

Van den Berghe G, Baxter RC, Weekers F, Wouters P, Bowers CY, Iranmanesh A, Veldhuis JD, Bouillon R. Van den Berghe G, et al. Clin Endocrinol (Oxf). 2002 May;56(5):655-69. doi: 10.1046/j.1365-2265.2002.01255.x. Clin Endocrinol (Oxf). 2002. PMID: 12030918 Clinical Trial.

Unequal impact of age, percentage body fat, and serum testosterone concentrations on the somatotrophic, IGF-I, and IGF-binding protein responses to a three-day intravenous growth hormone-releasing hormone pulsatile infusion in men.

Iranmanesh A, South S, Liem AY, Clemmons D, Thorner MO, Weltman A, Veldhuis JD. Iranmanesh A, et al. Eur J Endocrinol. 1998 Jul;139(1):59-71. doi: 10.1530/eje.0.1390059. Eur J Endocrinol. 1998. PMID: 9703380 Clinical Trial.

Sustained elevation of pulsatile growth hormone (GH) secretion and insulin-like growth factor I (IGF-I), IGF-binding protein-3 (IGFBP-3), and IGFBP-5 concentrations during 30-day continuous subcutaneous infusion of GH-releasing peptide-2 in older men and women.

Bowers CY, Granda R, Mohan S, Kuipers J, Baylink D, Veldhuis JD. Bowers CY, et al. J Clin Endocrinol Metab. 2004 May;89(5):2290-300. doi: 10.1210/jc.2003-031799. J Clin Endocrinol Metab. 2004. PMID: 15126555

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