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Items: 1 to 20 of 94


Essential function of the polo box of Cdc5 in subcellular localization and induction of cytokinetic structures.

Song S, Grenfell TZ, Garfield S, Erikson RL, Lee KS.

Mol Cell Biol. 2000 Jan;20(1):286-98.


Mutation of the polo-box disrupts localization and mitotic functions of the mammalian polo kinase Plk.

Lee KS, Grenfell TZ, Yarm FR, Erikson RL.

Proc Natl Acad Sci U S A. 1998 Aug 4;95(16):9301-6.


A novel function of Saccharomyces cerevisiae CDC5 in cytokinesis.

Song S, Lee KS.

J Cell Biol. 2001 Feb 5;152(3):451-69.


The Sak polo-box comprises a structural domain sufficient for mitotic subcellular localization.

Leung GC, Hudson JW, Kozarova A, Davidson A, Dennis JW, Sicheri F.

Nat Struct Biol. 2002 Oct;9(10):719-24.


Sak, a murine protein-serine/threonine kinase that is related to the Drosophila polo kinase and involved in cell proliferation.

Fode C, Motro B, Yousefi S, Heffernan M, Dennis JW.

Proc Natl Acad Sci U S A. 1994 Jul 5;91(14):6388-92.


Independent modulation of the kinase and polo-box activities of Cdc5 protein unravels unique roles in the maintenance of genome stability.

Ratsima H, Ladouceur AM, Pascariu M, Sauvé V, Salloum Z, Maddox PS, D'Amours D.

Proc Natl Acad Sci U S A. 2011 Oct 25;108(43):E914-23. doi: 10.1073/pnas.1106448108. Epub 2011 Oct 10.


The family of polo-like kinases.

Golsteyn RM, Lane HA, Mundt KE, Arnaud L, Nigg EA.

Prog Cell Cycle Res. 1996;2:107-14. Review.


Requirement for Bbp1p in the proper mitotic functions of Cdc5p in Saccharomyces cerevisiae.

Park CJ, Song S, Giddings TH Jr, Ro HS, Sakchaisri K, Park JE, Seong YS, Winey M, Lee KS.

Mol Biol Cell. 2004 Apr;15(4):1711-23. Epub 2004 Feb 6.


The polo box is required for multiple functions of Plx1 in mitosis.

Liu J, Lewellyn AL, Chen LG, Maller JL.

J Biol Chem. 2004 May 14;279(20):21367-73. Epub 2004 Mar 11.


The molecular basis for phosphodependent substrate targeting and regulation of Plks by the Polo-box domain.

Elia AE, Rellos P, Haire LF, Chao JW, Ivins FJ, Hoepker K, Mohammad D, Cantley LC, Smerdon SJ, Yaffe MB.

Cell. 2003 Oct 3;115(1):83-95.


Plk is an M-phase-specific protein kinase and interacts with a kinesin-like protein, CHO1/MKLP-1.

Lee KS, Yuan YL, Kuriyama R, Erikson RL.

Mol Cell Biol. 1995 Dec;15(12):7143-51.


Polo-box motif targets a centrosome regulator, RanGTPase.

Jang YJ, Ji JH, Ahn JH, Hoe KL, Won M, Im DS, Chae SK, Song S, Yoo HS.

Biochem Biophys Res Commun. 2004 Dec 3;325(1):257-64.


Malignant transformation of mammalian cells initiated by constitutive expression of the polo-like kinase.

Smith MR, Wilson ML, Hamanaka R, Chase D, Kung H, Longo DL, Ferris DK.

Biochem Biophys Res Commun. 1997 May 19;234(2):397-405.


Polo box domain of Plk3 functions as a centrosome localization signal, overexpression of which causes mitotic arrest, cytokinesis defects, and apoptosis.

Jiang N, Wang X, Jhanwar-Uniyal M, Darzynkiewicz Z, Dai W.

J Biol Chem. 2006 Apr 14;281(15):10577-82. Epub 2006 Feb 14.


Identification and cloning of a protein kinase-encoding mouse gene, Plk, related to the polo gene of Drosophila.

Clay FJ, McEwen SJ, Bertoncello I, Wilks AF, Dunn AR.

Proc Natl Acad Sci U S A. 1993 Jun 1;90(11):4882-6.


Structure-function relationship of the Polo-like kinase in Trypanosoma brucei.

Yu Z, Liu Y, Li Z.

J Cell Sci. 2012 Mar 15;125(Pt 6):1519-30. doi: 10.1242/jcs.094243. Epub 2012 Jan 24.

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