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Results: 1 to 20 of 128

1.

Potential antipsoriatic agents: lapacho compounds as potent inhibitors of HaCaT cell growth.

Müller K, Sellmer A, Wiegrebe W.

J Nat Prod. 1999 Aug;62(8):1134-6.

PMID:
10479319
[PubMed - indexed for MEDLINE]
2.

10-omega-phenylalkyl-9(10H)-anthracenones as inhibitors of keratinocyte growth with reduced membrane damaging properties.

Müller K, Breu K.

Bioorg Med Chem Lett. 1998 Nov 17;8(22):3211-6.

PMID:
9873705
[PubMed - indexed for MEDLINE]
4.

10-Phenylbutyryl-substituted anthracenones as inhibitors of keratinocyte growth and LTB(4) biosynthesis.

Müller K, Breu K, Reindl H.

Eur J Med Chem. 2001 Feb;36(2):179-84.

PMID:
11311748
[PubMed - indexed for MEDLINE]
5.

Heterocyclic substituted anthralin derivatives as inhibitors of keratinocyte growth and inducers of differentiation.

Müller K, Reindl H, Breu K.

Bioorg Med Chem Lett. 2001 Jan 8;11(1):47-50.

PMID:
11140730
[PubMed - indexed for MEDLINE]
6.

Structure-activity relationship studies of acridones as potential antipsoriatic agents. 1. Synthesis and antiproliferative activity of simple N-unsubstituted 10H-acridin-9-ones against human keratinocyte growth.

Putic A, Stecher L, Prinz H, Müller K.

Eur J Med Chem. 2010 Aug;45(8):3299-310. doi: 10.1016/j.ejmech.2010.04.013. Epub 2010 Apr 18.

PMID:
20452101
[PubMed - indexed for MEDLINE]
7.

Synthesis and structure-activity relationships of lapacho analogues. 1. Suppression of human keratinocyte hyperproliferation by 2-substituted naphtho[2,3-b]furan-4,9-diones, activation by enzymatic one- and two-electron reduction, and intracellular generation of superoxide.

Reichstein A, Vortherms S, Bannwitz S, Tentrop J, Prinz H, Müller K.

J Med Chem. 2012 Aug 23;55(16):7273-84. doi: 10.1021/jm3009597. Epub 2012 Aug 7.

PMID:
22845014
[PubMed - indexed for MEDLINE]
8.

Structure-activity relationship studies of acridones as potential antipsoriatic agents. 2. Synthesis and antiproliferative activity of 10-substituted hydroxy-10H-acridin-9-ones against human keratinocyte growth.

Putic A, Stecher L, Prinz H, Müller K.

Eur J Med Chem. 2010 Nov;45(11):5345-52. doi: 10.1016/j.ejmech.2010.08.059. Epub 2010 Sep 20.

PMID:
20850910
[PubMed - indexed for MEDLINE]
9.

10-alpha-Aminoacyl-9(10H)-anthracenones: inhibition of 12(S)-HETE biosynthesis and HaCaT cell growth.

Müller K, Breu K.

Arch Pharm (Weinheim). 1999 Jan;332(1):31-5.

PMID:
10073141
[PubMed - indexed for MEDLINE]
10.

Simple analogues of anthralin: unusual specificity of structure and antiproliferative activity.

Müller K, Prinz H, Gawlik I, Ziereis K, Huang HS.

J Med Chem. 1997 Nov 7;40(23):3773-80.

PMID:
9371243
[PubMed - indexed for MEDLINE]
12.

Cornified envelope formation by anthralin, simple analogues, and related anthracenones.

Müller K, Reindl H.

Arch Pharm (Weinheim). 2001 Mar;334(3):86-92.

PMID:
11315339
[PubMed - indexed for MEDLINE]
13.

Synthesis and structure-activity relationships of lapacho analogues. 2. Modification of the basic naphtho[2,3-b]furan-4,9-dione, redox activation, and suppression of human keratinocyte hyperproliferation by 8-hydroxynaphtho[2,3-b]thiophene-4,9-diones.

Bannwitz S, Krane D, Vortherms S, Kalin T, Lindenschmidt C, Zahedi Golpayegani N, Tentrop J, Prinz H, Müller K.

J Med Chem. 2014 Jul 24;57(14):6226-39. doi: 10.1021/jm500754d. Epub 2014 Jul 7.

PMID:
24964246
[PubMed - in process]
14.

Comparison of antiproliferative effects of experimental and established antipsoriatic drugs on human keratinocytes, using a simple 96-well-plate assay.

Pol A, Bergers M, Schalkwijk J.

In Vitro Cell Dev Biol Anim. 2003 Jan-Feb;39(1-2):36-42.

PMID:
12892525
[PubMed - indexed for MEDLINE]
15.

Structure-function relationship of new anthralin derivatives assayed for growth inhibition and cytotoxicity in human keratinocyte cultures.

Bonnekoh B, Tanzer H, Seidel M, Geisel J, Merk HF, Mahrle G, Wiegrebe W.

Arch Pharm (Weinheim). 1991 Nov;324(11):899-906.

PMID:
1804068
[PubMed - indexed for MEDLINE]
16.

The antipsoriatic Mahonia aquifolium and its active constituents; II. Antiproliferative activity against cell growth of human keratinocytes.

Müller K, Ziereis K, Gawlik I.

Planta Med. 1995 Feb;61(1):74-5.

PMID:
7700998
[PubMed - indexed for MEDLINE]
17.

Dithranol upregulates IL-10 receptors on the cultured human keratinocyte cell line HaCaT.

Farkas A, Kemény L, Szöny BJ, Bata-Csörgö Z, Pivarcsi A, Kiss M, Széll M, Koreck A, Dobozy A.

Inflamm Res. 2001 Jan;50(1):44-9.

PMID:
11235021
[PubMed - indexed for MEDLINE]
18.

Potential antipsoriatic avarol derivatives as antioxidants and inhibitors of PGE(2) generation and proliferation in the HaCaT cell line.

Amigó M, Terencio MC, Mitova M, Iodice C, Payá M, De Rosa S.

J Nat Prod. 2004 Sep;67(9):1459-63.

PMID:
15387642
[PubMed - indexed for MEDLINE]
19.

Red Lapacho (Tabebuia impetiginosa)--a global ethnopharmacological commodity?

Gómez Castellanos JR, Prieto JM, Heinrich M.

J Ethnopharmacol. 2009 Jan 12;121(1):1-13. doi: 10.1016/j.jep.2008.10.004. Epub 2008 Nov 1. Review.

PMID:
18992801
[PubMed - indexed for MEDLINE]
20.

Antipsoriatic anthrones with modulated redox properties. 2. Novel derivatives of chrysarobin and isochrysarobin--antiproliferative activity and 5-lipoxygenase inhibition.

Müller K, Leukel P, Ziereis K, Gawlik I.

J Med Chem. 1994 May 27;37(11):1660-9.

PMID:
8201600
[PubMed - indexed for MEDLINE]

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