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Results: 1 to 20 of 134

1.

Evidence that tristetraprolin binds to AU-rich elements and promotes the deadenylation and destabilization of tumor necrosis factor alpha mRNA.

Lai WS, Carballo E, Strum JR, Kennington EA, Phillips RS, Blackshear PJ.

Mol Cell Biol. 1999 Jun;19(6):4311-23.

PMID:
10330172
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Interactions of CCCH zinc finger proteins with mRNA. Binding of tristetraprolin-related zinc finger proteins to Au-rich elements and destabilization of mRNA.

Lai WS, Carballo E, Thorn JM, Kennington EA, Blackshear PJ.

J Biol Chem. 2000 Jun 9;275(23):17827-37.

PMID:
10751406
[PubMed - indexed for MEDLINE]
Free Article
3.
4.

Interactions of CCCH zinc finger proteins with mRNA: non-binding tristetraprolin mutants exert an inhibitory effect on degradation of AU-rich element-containing mRNAs.

Lai WS, Kennington EA, Blackshear PJ.

J Biol Chem. 2002 Mar 15;277(11):9606-13. Epub 2002 Jan 8.

PMID:
11782475
[PubMed - indexed for MEDLINE]
Free Article
5.

Interactions of CCCH zinc finger proteins with mRNA: tristetraprolin-mediated AU-rich element-dependent mRNA degradation can occur in the absence of a poly(A) tail.

Lai WS, Blackshear PJ.

J Biol Chem. 2001 Jun 22;276(25):23144-54. Epub 2001 Mar 28.

PMID:
11279239
[PubMed - indexed for MEDLINE]
Free Article
6.

Chorioallantoic fusion defects and embryonic lethality resulting from disruption of Zfp36L1, a gene encoding a CCCH tandem zinc finger protein of the Tristetraprolin family.

Stumpo DJ, Byrd NA, Phillips RS, Ghosh S, Maronpot RR, Castranio T, Meyers EN, Mishina Y, Blackshear PJ.

Mol Cell Biol. 2004 Jul;24(14):6445-55.

PMID:
15226444
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Identification of four CCCH zinc finger proteins in Xenopus, including a novel vertebrate protein with four zinc fingers and severely restricted expression.

De J, Lai WS, Thorn JM, Goldsworthy SM, Liu X, Blackwell TK, Blackshear PJ.

Gene. 1999 Mar 4;228(1-2):133-45.

PMID:
10072766
[PubMed - indexed for MEDLINE]
9.

Zfp36l3, a rodent X chromosome gene encoding a placenta-specific member of the Tristetraprolin family of CCCH tandem zinc finger proteins.

Blackshear PJ, Phillips RS, Ghosh S, Ramos SB, Richfield EK, Lai WS.

Biol Reprod. 2005 Aug;73(2):297-307. Epub 2005 Apr 6. Erratum in: Biol Reprod. 2005 Nov;73(5):1072. Ramos, Silvia V B [corrected to Ramos, Silvia B V].

PMID:
15814898
[PubMed - indexed for MEDLINE]
Free Article
10.

The tandem CCCH zinc finger protein tristetraprolin and its relevance to cytokine mRNA turnover and arthritis.

Carrick DM, Lai WS, Blackshear PJ.

Arthritis Res Ther. 2004;6(6):248-64. Epub 2004 Oct 8. Review.

PMID:
15535838
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Roles of tumor necrosis factor-alpha receptor subtypes in the pathogenesis of the tristetraprolin-deficiency syndrome.

Carballo E, Blackshear PJ.

Blood. 2001 Oct 15;98(8):2389-95.

PMID:
11588035
[PubMed - indexed for MEDLINE]
Free Article
12.

Tristetraprolin and its family members can promote the cell-free deadenylation of AU-rich element-containing mRNAs by poly(A) ribonuclease.

Lai WS, Kennington EA, Blackshear PJ.

Mol Cell Biol. 2003 Jun;23(11):3798-812.

PMID:
12748283
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Feedback inhibition of macrophage tumor necrosis factor-alpha production by tristetraprolin.

Carballo E, Lai WS, Blackshear PJ.

Science. 1998 Aug 14;281(5379):1001-5.

PMID:
9703499
[PubMed - indexed for MEDLINE]
Free Article
14.

Direct binding of specific AUF1 isoforms to tandem zinc finger domains of tristetraprolin (TTP) family proteins.

Kedar VP, Zucconi BE, Wilson GM, Blackshear PJ.

J Biol Chem. 2012 Feb 17;287(8):5459-71. doi: 10.1074/jbc.M111.312652. Epub 2011 Dec 27.

PMID:
22203679
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Members of the tristetraprolin family of tandem CCCH zinc finger proteins exhibit CRM1-dependent nucleocytoplasmic shuttling.

Phillips RS, Ramos SB, Blackshear PJ.

J Biol Chem. 2002 Mar 29;277(13):11606-13. Epub 2002 Jan 16.

PMID:
11796723
[PubMed - indexed for MEDLINE]
Free Article
16.

The stability of tristetraprolin mRNA is regulated by mitogen-activated protein kinase p38 and by tristetraprolin itself.

Tchen CR, Brook M, Saklatvala J, Clark AR.

J Biol Chem. 2004 Jul 30;279(31):32393-400. Epub 2004 Jun 7.

PMID:
15187092
[PubMed - indexed for MEDLINE]
Free Article
17.

Inhibition of tristetraprolin deadenylation by poly(A) binding protein.

Rowlett RM, Chrestensen CA, Schroeder MJ, Harp MG, Pelo JW, Shabanowitz J, DeRose R, Hunt DF, Sturgill TW, Worthington MT.

Am J Physiol Gastrointest Liver Physiol. 2008 Sep;295(3):G421-30. doi: 10.1152/ajpgi.00508.2007. Epub 2008 May 8.

PMID:
18467502
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

AU-rich element-mediated translational control: complexity and multiple activities of trans-activating factors.

Zhang T, Kruys V, Huez G, Gueydan C.

Biochem Soc Trans. 2002 Nov;30(Pt 6):952-8. Review.

PMID:
12440953
[PubMed - indexed for MEDLINE]
19.

Characteristics of the interaction of a synthetic human tristetraprolin tandem zinc finger peptide with AU-rich element-containing RNA substrates.

Blackshear PJ, Lai WS, Kennington EA, Brewer G, Wilson GM, Guan X, Zhou P.

J Biol Chem. 2003 May 30;278(22):19947-55. Epub 2003 Mar 14.

PMID:
12639954
[PubMed - indexed for MEDLINE]
Free Article
20.

Tristetraprolin and other CCCH tandem zinc-finger proteins in the regulation of mRNA turnover.

Blackshear PJ.

Biochem Soc Trans. 2002 Nov;30(Pt 6):945-52. Review.

PMID:
12440952
[PubMed - indexed for MEDLINE]

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