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Items: 1 to 20 of 647


Phosphorylation of Tyr319 in ZAP-70 is required for T-cell antigen receptor-dependent phospholipase C-gamma1 and Ras activation.

Williams BL, Irvin BJ, Sutor SL, Chini CC, Yacyshyn E, Bubeck Wardenburg J, Dalton M, Chan AC, Abraham RT.

EMBO J. 1999 Apr 1;18(7):1832-44.


Uncoupling of nonreceptor tyrosine kinases from PLC-gamma1 in an SLP-76-deficient T cell.

Yablonski D, Kuhne MR, Kadlecek T, Weiss A.

Science. 1998 Jul 17;281(5375):413-6.


Alternative antigen receptor (TCR) signaling in T cells derived from ZAP-70-deficient patients expressing high levels of Syk.

Noraz N, Schwarz K, Steinberg M, Dardalhon V, Rebouissou C, Hipskind R, Friedrich W, Yssel H, Bacon K, Taylor N.

J Biol Chem. 2000 May 26;275(21):15832-8.


Zap-70-independent Ca(2+) mobilization and Erk activation in Jurkat T cells in response to T-cell antigen receptor ligation.

Shan X, Balakir R, Criado G, Wood JS, Seminario MC, Madrenas J, Wange RL.

Mol Cell Biol. 2001 Nov;21(21):7137-49.


T cell-specific adapter protein inhibits T cell activation by modulating Lck activity.

Sundvold V, Torgersen KM, Post NH, Marti F, King PD, Røttingen JA, Spurkland A, Lea T.

J Immunol. 2000 Sep 15;165(6):2927-31.


Reconstitution of T cell antigen receptor-induced Erk2 kinase activation in Lck-negative JCaM1 cells by Syk.

Williams S, Couture C, Gilman J, Jascur T, Deckert M, Altman A, Mustelin T.

Eur J Biochem. 1997 Apr 1;245(1):84-90.


70Z/3 Cbl induces PLC gamma 1 activation in T lymphocytes via an alternate Lat- and Slp-76-independent signaling mechanism.

Graham LJ, Verí MC, DeBell KE, Noviello C, Rawat R, Jen S, Bonvini E, Rellahan B.

Oncogene. 2003 Apr 24;22(16):2493-503.


Interdomain B in ZAP-70 regulates but is not required for ZAP-70 signaling function in lymphocytes.

Zhao Q, Williams BL, Abraham RT, Weiss A.

Mol Cell Biol. 1999 Jan;19(1):948-56.


Biochemical interactions integrating Itk with the T cell receptor-initiated signaling cascade.

Bunnell SC, Diehn M, Yaffe MB, Findell PR, Cantley LC, Berg LJ.

J Biol Chem. 2000 Jan 21;275(3):2219-30.


Mutation of tyrosines 492/493 in the kinase domain of ZAP-70 affects multiple T-cell receptor signaling pathways.

Mège D, Di Bartolo V, Germain V, Tuosto L, Michel F, Acuto O.

J Biol Chem. 1996 Dec 20;271(51):32644-52.


LAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathway.

Finco TS, Kadlecek T, Zhang W, Samelson LE, Weiss A.

Immunity. 1998 Nov;9(5):617-26.

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