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Items: 1 to 20 of 1764


Kazinol-E is a specific inhibitor of ERK that suppresses the enrichment of a breast cancer stem-like cell population.

Jung YC, Han S, Hua L, Ahn YH, Cho H, Lee CJ, Lee H, Cho YY, Ryu JH, Jeon R, Kim WY.

Biochem Biophys Res Commun. 2016 Feb 5;470(2):294-9. doi: 10.1016/j.bbrc.2016.01.066. Epub 2016 Jan 13.


ERK2-Pyruvate Kinase Axis Permits Phorbol 12-Myristate 13-Acetate-induced Megakaryocyte Differentiation in K562 Cells.

Chaman N, Iqbal MA, Siddiqui FA, Gopinath P, Bamezai RN.

J Biol Chem. 2015 Sep 25;290(39):23803-15. doi: 10.1074/jbc.M115.657411. Epub 2015 Aug 12.


Vitamin D Promotes Odontogenic Differentiation of Human Dental Pulp Cells via ERK Activation.

Woo SM, Lim HS, Jeong KY, Kim SM, Kim WJ, Jung JY.

Mol Cells. 2015 Jul;38(7):604-9. doi: 10.14348/molcells.2015.2318. Epub 2015 Jun 10.


Histamine activates p38 MAP kinase and alters local lamellipodia dynamics, reducing endothelial barrier integrity and eliciting central movement of actin fibers.

Adderley SP, Lawrence C, Madonia E, Olubadewo JO, Breslin JW.

Am J Physiol Cell Physiol. 2015 Jul 1;309(1):C51-9. doi: 10.1152/ajpcell.00096.2015. Epub 2015 May 6.


The effect of BMS-582949, a P38 mitogen-activated protein kinase (P38 MAPK) inhibitor on arterial inflammation: a multicenter FDG-PET trial.

Emami H, Vucic E, Subramanian S, Abdelbaky A, Fayad ZA, Du S, Roth E, Ballantyne CM, Mohler ER, Farkouh ME, Kim J, Farmer M, Li L, Ehlgen A, Langenickel TH, Velasquez L, Hayes W, Tawakol A.

Atherosclerosis. 2015 Jun;240(2):490-6. doi: 10.1016/j.atherosclerosis.2015.03.039. Epub 2015 Mar 28.


Erk2 but not Erk1 regulates crosstalk between Met and EGFR in squamous cell carcinoma cell lines.

Gusenbauer S, Zanucco E, Knyazev P, Ullrich A.

Mol Cancer. 2015 Mar 4;14:54. doi: 10.1186/s12943-015-0319-z.


Sesamin inhibits lipopolysaccharide-induced proliferation and invasion through the p38-MAPK and NF-κB signaling pathways in prostate cancer cells.

Xu P, Cai F, Liu X, Guo L.

Oncol Rep. 2015 Jun;33(6):3117-23. doi: 10.3892/or.2015.3888. Epub 2015 Mar 31.


Reversal of corticosteroid insensitivity by p38 MAPK inhibition in peripheral blood mononuclear cells from COPD.

Khorasani N, Baker J, Johnson M, Chung KF, Bhavsar PK.

Int J Chron Obstruct Pulmon Dis. 2015 Feb 4;10:283-91. doi: 10.2147/COPD.S72403. eCollection 2015.


Berberine induces FasL-related apoptosis through p38 activation in KB human oral cancer cells.

Kim JS, Oh D, Yim MJ, Park JJ, Kang KR, Cho IA, Moon SM, Oh JS, You JS, Kim CS, Kim DK, Lee SY, Lee GJ, Im HJ, Kim SG.

Oncol Rep. 2015 Apr;33(4):1775-82. doi: 10.3892/or.2015.3768. Epub 2015 Jan 29.


Piperlongumine induces apoptotic and autophagic death of the primary myeloid leukemia cells from patients via activation of ROS-p38/JNK pathways.

Xiong XX, Liu JM, Qiu XY, Pan F, Yu SB, Chen XQ.

Acta Pharmacol Sin. 2015 Mar;36(3):362-74. doi: 10.1038/aps.2014.141. Epub 2015 Jan 26.


Activation of villous trophoblastic p38 and ERK1/2 signaling pathways in preterm preeclampsia and HELLP syndrome.

Szabo S, Mody M, Romero R, Xu Y, Karaszi K, Mihalik N, Xu Z, Bhatti G, Fule T, Hupuczi P, Krenacs T, Rigo J Jr, Tarca AL, Hassan SS, Chaiworapongsa T, Kovalszky I, Papp Z, Than NG.

Pathol Oncol Res. 2015 Jul;21(3):659-68. doi: 10.1007/s12253-014-9872-9. Epub 2015 Jan 13.


Endothelial progenitor cells proliferated via MEK-dependent p42 MAPK signaling pathway.

Sandra F, Oktaviono YH, Widodo MA, Dirgantara Y, Chouw A, Sargowo D.

Mol Cell Biochem. 2015 Feb;400(1-2):201-6. doi: 10.1007/s11010-014-2276-z. Epub 2014 Nov 25.


Mitogen-activated protein kinase signal transduction in solid tumors.

Lei YY, Wang WJ, Mei JH, Wang CL.

Asian Pac J Cancer Prev. 2014;15(20):8539-48. Review.


Integrative analysis of ocular complications in atherosclerosis unveils pathway convergence and crosstalk.

Gupta A, Mohanty P, Bhatnagar S.

J Recept Signal Transduct Res. 2015 Apr;35(2):149-64. doi: 10.3109/10799893.2014.942462. Epub 2014 Jul 23.


Mitogen-activated protein kinases pathways mediate the sunitinib-induced hypertrophy in rat cardiomyocyte H9c2 cells.

Korashy HM, Al-Suwayeh HA, Maayah ZH, Ansari MA, Ahmad SF, Bakheet SA.

Cardiovasc Toxicol. 2015 Jan;15(1):41-51. doi: 10.1007/s12012-014-9266-y.


Obacunone exhibits anti-proliferative and anti-aromatase activity in vitro by inhibiting the p38 MAPK signaling pathway in MCF-7 human breast adenocarcinoma cells.

Kim J, Jayaprakasha GK, Patil BS.

Biochimie. 2014 Oct;105:36-44. doi: 10.1016/j.biochi.2014.06.002. Epub 2014 Jun 11.


Lipoxin A4 suppresses the development of endometriosis in an ALX receptor-dependent manner via the p38 MAPK pathway.

Wu R, Zhou W, Chen S, Shi Y, Su L, Zhu M, Chen Q, Chen Q.

Br J Pharmacol. 2014 Nov;171(21):4927-40. doi: 10.1111/bph.12816.


Cadmium induces vascular permeability via activation of the p38 MAPK pathway.

Dong F, Guo F, Li L, Guo L, Hou Y, Hao E, Yan S, Allen TD, Liu J.

Biochem Biophys Res Commun. 2014 Jul 18;450(1):447-52. doi: 10.1016/j.bbrc.2014.05.140. Epub 2014 Jun 6.


Activity of sputum p38 MAPK is correlated with airway inflammation and reduced FEV1 in COPD patients.

Huang C, Xie M, He X, Gao H.

Med Sci Monit. 2013 Dec 31;19:1229-35. doi: 10.12659/MSM.889880.

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