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PubMed Links for Gene (Select 13858)


The endocytic adaptor Eps15 controls marginal zone B cell numbers.

Pozzi B, Amodio S, Lucano C, Sciullo A, Ronzoni S, Castelletti D, Adler T, Treise I, Betsholtz IH, Rathkolb B, Busch DH, Wolf E, Fuchs H, Gailus-Durner V, de Angelis MH, Betsholtz C, Casola S, Di Fiore PP, Offenhäuser N.

PLoS One. 2012;7(11):e50818. doi: 10.1371/journal.pone.0050818. Epub 2012 Nov 30.


Sequence-based characterization of structural variation in the mouse genome.

Yalcin B, Wong K, Agam A, Goodson M, Keane TM, Gan X, Nellåker C, Goodstadt L, Nicod J, Bhomra A, Hernandez-Pliego P, Whitley H, Cleak J, Dutton R, Janowitz D, Mott R, Adams DJ, Flint J.

Nature. 2011 Sep 14;477(7364):326-9. doi: 10.1038/nature10432.


Mouse hepatitis virus type 2 enters cells through a clathrin-mediated endocytic pathway independent of Eps15.

Pu Y, Zhang X.

J Virol. 2008 Aug;82(16):8112-23. doi: 10.1128/JVI.00837-08. Epub 2008 Jun 11.


The EH1 domain of Eps15 is structurally classified as a member of the S100 subclass of EF-hand-containing proteins.

Whitehead B, Tessari M, Carotenuto A, van Bergen en Henegouwen PM, Vuister GW.

Biochemistry. 1999 Aug 31;38(35):11271-7.


Eps15 is a component of clathrin-coated pits and vesicles and is located at the rim of coated pits.

Tebar F, Sorkina T, Sorkin A, Ericsson M, Kirchhausen T.

J Biol Chem. 1996 Nov 15;271(46):28727-30.


eps15, a novel tyrosine kinase substrate, exhibits transforming activity.

Fazioli F, Minichiello L, Matoskova B, Wong WT, Di Fiore PP.

Mol Cell Biol. 1993 Sep;13(9):5814-28.


Binding to DPF-motif by the POB1 EH domain is responsible for POB1-Eps15 interaction.

Santonico E, Panni S, Falconi M, Castagnoli L, Cesareni G.

BMC Biochem. 2007 Dec 21;8:29.


Eps15 is constitutively oligomerized due to homophilic interaction of its coiled-coil region.

Tebar F, Confalonieri S, Carter RE, Di Fiore PP, Sorkin A.

J Biol Chem. 1997 Jun 13;272(24):15413-8.


The Troyer syndrome (SPG20) protein spartin interacts with Eps15.

Bakowska JC, Jenkins R, Pendleton J, Blackstone C.

Biochem Biophys Res Commun. 2005 Sep 9;334(4):1042-8.


c-Cbl directs EGF receptors into an endocytic pathway that involves the ubiquitin-interacting motif of Eps15.

de Melker AA, van der Horst G, Borst J.

J Cell Sci. 2004 Oct 1;117(Pt 21):5001-12. Epub 2004 Sep 21.


Differential patterns of expression of Eps15 and Eps15R during mouse embryogenesis.

Offenhäuser N, Santolini E, Simeone A, Di Fiore PP.

Mech Dev. 2000 Jul;95(1-2):309-12.


Expression of the receptor tyrosine kinase substrate genes eps8 and eps15 during mouse development.

Avantaggiato V, Torino A, Wong WT, Di Fiore PP, Simeone A.

Oncogene. 1995 Sep 21;11(6):1191-8.


The ciliary pocket: an endocytic membrane domain at the base of primary and motile cilia.

Molla-Herman A, Ghossoub R, Blisnick T, Meunier A, Serres C, Silbermann F, Emmerson C, Romeo K, Bourdoncle P, Schmitt A, Saunier S, Spassky N, Bastin P, Benmerah A.

J Cell Sci. 2010 May 15;123(Pt 10):1785-95. doi: 10.1242/jcs.059519. Epub 2010 Apr 27.


An endosomally localized isoform of Eps15 interacts with Hrs to mediate degradation of epidermal growth factor receptor.

Roxrud I, Raiborg C, Pedersen NM, Stang E, Stenmark H.

J Cell Biol. 2008 Mar 24;180(6):1205-18. doi: 10.1083/jcb.200708115.


Characterization of a gamma-adaptin ear-binding motif in enthoprotin.

Wasiak S, Denisov AY, Han Z, Leventis PA, de Heuvel E, Boulianne GL, Kay BK, Gehring K, McPherson PS.

FEBS Lett. 2003 Dec 18;555(3):437-42.


Tyrosine phosphorylation of Eps15 is required for ligand-regulated, but not constitutive, endocytosis.

Confalonieri S, Salcini AE, Puri C, Tacchetti C, Di Fiore PP.

J Cell Biol. 2000 Aug 21;150(4):905-12.


An actin-binding protein of the Sla2/Huntingtin interacting protein 1 family is a novel component of clathrin-coated pits and vesicles.

Engqvist-Goldstein AE, Kessels MM, Chopra VS, Hayden MR, Drubin DG.

J Cell Biol. 1999 Dec 27;147(7):1503-18.


Eps15R is a tyrosine kinase substrate with characteristics of a docking protein possibly involved in coated pits-mediated internalization.

Coda L, Salcini AE, Confalonieri S, Pelicci G, Sorkina T, Sorkin A, Pelicci PG, Di Fiore PP.

J Biol Chem. 1998 Jan 30;273(5):3003-12.


A single motif responsible for ubiquitin recognition and monoubiquitination in endocytic proteins.

Polo S, Sigismund S, Faretta M, Guidi M, Capua MR, Bossi G, Chen H, De Camilli P, Di Fiore PP.

Nature. 2002 Mar 28;416(6879):451-5.


The Eps15 C. elegans homologue EHS-1 is implicated in synaptic vesicle recycling.

Salcini AE, Hilliard MA, Croce A, Arbucci S, Luzzi P, Tacchetti C, Daniell L, De Camilli P, Pelicci PG, Di Fiore PP, Bazzicalupo P.

Nat Cell Biol. 2001 Aug;3(8):755-60. Erratum in: Nat Cell Biol 2001 Oct;3(10):943.

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