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Results: 1 to 20 of 245

1.

The determinants of head and neck cancer: Unmasking the PI3K pathway mutations.

Giudice FS, Squarize CH.

J Carcinog Mutagen. 2013 Aug 2;Suppl 5. pii: 003.

PMID:
25126449
[PubMed]
Free PMC Article
2.

mTOR in viral hepatitis and hepatocellular carcinoma: function and treatment.

Wang Z, Jin W, Jin H, Wang X.

Biomed Res Int. 2014;2014:735672. doi: 10.1155/2014/735672. Epub 2014 Apr 2.

PMID:
24804240
[PubMed - in process]
Free PMC Article
3.

PI3K-AKT-mTOR signaling in prostate cancer progression and androgen deprivation therapy resistance.

Edlind MP, Hsieh AC.

Asian J Androl. 2014 May-Jun;16(3):378-86. doi: 10.4103/1008-682X.122876.

PMID:
24759575
[PubMed - in process]
Free PMC Article
4.

Cutting through the complexities of mTOR for the treatment of stroke.

Maiese K.

Curr Neurovasc Res. 2014 May;11(2):177-86.

PMID:
24712647
[PubMed - in process]
Free PMC Article
5.

14-3-3 Proteins are Regulators of Autophagy.

Pozuelo-Rubio M.

Cells. 2012 Oct 15;1(4):754-73. doi: 10.3390/cells1040754.

PMID:
24710529
[PubMed]
Free PMC Article
6.

Identification of the novel interacting partners of the mammalian target of rapamycin complex 1 in human CCRF-CEM and HEK293 cells.

Rahman H, Qasim M, Oellerich M, Asif AR.

Int J Mol Sci. 2014 Mar 18;15(3):4823-36. doi: 10.3390/ijms15034823.

PMID:
24646917
[PubMed - in process]
Free PMC Article
7.

AMPK: regulating energy balance at the cellular and whole body levels.

Hardie DG, Ashford ML.

Physiology (Bethesda). 2014 Mar;29(2):99-107. doi: 10.1152/physiol.00050.2013.

PMID:
24583766
[PubMed - in process]
Free PMC Article
8.

PI3K-AKT-mTOR-signaling and beyond: the complex network in gastroenteropancreatic neuroendocrine neoplasms.

Briest F, Grabowski P.

Theranostics. 2014 Jan 29;4(4):336-65. doi: 10.7150/thno.7851. eCollection 2014. Review.

PMID:
24578720
[PubMed - in process]
Free PMC Article
9.

The mTOR pathway controls cell proliferation by regulating the FoxO3a transcription factor via SGK1 kinase.

Mori S, Nada S, Kimura H, Tajima S, Takahashi Y, Kitamura A, Oneyama C, Okada M.

PLoS One. 2014 Feb 18;9(2):e88891. doi: 10.1371/journal.pone.0088891. eCollection 2014.

PMID:
24558442
[PubMed - in process]
Free PMC Article
10.

Discrete mechanisms of mTOR and cell cycle regulation by AMPK agonists independent of AMPK.

Liu X, Chhipa RR, Pooya S, Wortman M, Yachyshin S, Chow LM, Kumar A, Zhou X, Sun Y, Quinn B, McPherson C, Warnick RE, Kendler A, Giri S, Poels J, Norga K, Viollet B, Grabowski GA, Dasgupta B.

Proc Natl Acad Sci U S A. 2014 Jan 28;111(4):E435-44. doi: 10.1073/pnas.1311121111. Epub 2014 Jan 13.

PMID:
24474794
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

PRAS40 prevents development of diabetic cardiomyopathy and improves hepatic insulin sensitivity in obesity.

Völkers M, Doroudgar S, Nguyen N, Konstandin MH, Quijada P, Din S, Ornelas L, Thuerauf DJ, Gude N, Friedrich K, Herzig S, Glembotski CC, Sussman MA.

EMBO Mol Med. 2014 Jan;6(1):57-65. doi: 10.1002/emmm.201303183.

PMID:
24408966
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Overexpression of PTEN suppresses lipopolysaccharide-induced lung fibroblast proliferation, differentiation and collagen secretion through inhibition of the PI3-K-Akt-GSK3beta pathway.

He Z, Deng Y, Li W, Chen Y, Xing S, Zhao X, Ding J, Gao Y, Wang X.

Cell Biosci. 2014 Jan 6;4(1):2. doi: 10.1186/2045-3701-4-2.

PMID:
24387036
[PubMed]
Free PMC Article
13.

The regulation of the autophagic network and its implications for human disease.

Yang J, Carra S, Zhu WG, Kampinga HH.

Int J Biol Sci. 2013 Dec 1;9(10):1121-33. doi: 10.7150/ijbs.6666. eCollection 2013. Review.

PMID:
24339733
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Mammalian target of rapamycin complex I (mTORC1) activity in ras homologue enriched in brain (Rheb)-deficient mouse embryonic fibroblasts.

Groenewoud MJ, Goorden SM, Kassies J, Pellis-van Berkel W, Lamb RF, Elgersma Y, Zwartkruis FJ.

PLoS One. 2013 Nov 26;8(11):e81649. doi: 10.1371/journal.pone.0081649. eCollection 2013.

PMID:
24303063
[PubMed - in process]
Free PMC Article
15.

What a tangled web we weave: emerging resistance mechanisms to inhibition of the phosphoinositide 3-kinase pathway.

Klempner SJ, Myers AP, Cantley LC.

Cancer Discov. 2013 Dec;3(12):1345-54. doi: 10.1158/2159-8290.CD-13-0063. Epub 2013 Nov 21. Review.

PMID:
24265156
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Targeting the Mammalian Target of Rapamycin (mTOR) in Cancer Therapy: Lessons from Past and Future Perspectives.

Dufour M, Dormond-Meuwly A, Demartines N, Dormond O.

Cancers (Basel). 2011 May 24;3(2):2478-500. doi: 10.3390/cancers3022478.

PMID:
24212820
[PubMed]
Free PMC Article
17.

Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signalling to suppress tumorigenesis.

Liu P, Gan W, Inuzuka H, Lazorchak AS, Gao D, Arojo O, Liu D, Wan L, Zhai B, Yu Y, Yuan M, Kim BM, Shaik S, Menon S, Gygi SP, Lee TH, Asara JM, Manning BD, Blenis J, Su B, Wei W.

Nat Cell Biol. 2013 Nov;15(11):1340-50. doi: 10.1038/ncb2860. Epub 2013 Oct 27.

PMID:
24161930
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

mTOR/PRAS40 interaction: hypertrophy or proliferation.

Völkers M, Sussman M.

Cell Cycle. 2013 Dec 1;12(23):3579-80. doi: 10.4161/cc.26822. Epub 2013 Oct 21. No abstract available.

PMID:
24131922
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Impaired hypothalamic mTOR activation in the adult rat offspring born to mothers fed a low-protein diet.

Guzmán-Quevedo O, Da Silva Aragão R, Pérez García G, Matos RJ, de Sa Braga Oliveira A, Manhães de Castro R, Bolaños-Jiménez F.

PLoS One. 2013 Sep 9;8(9):e74990. doi: 10.1371/journal.pone.0074990. eCollection 2013.

PMID:
24040371
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

AKT-independent PI3-K signaling in cancer - emerging role for SGK3.

Bruhn MA, Pearson RB, Hannan RD, Sheppard KE.

Cancer Manag Res. 2013 Aug 26;5:281-92. doi: 10.2147/CMAR.S35178. eCollection 2013. Review.

PMID:
24009430
[PubMed]
Free PMC Article

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