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Results: 1 to 20 of 123

1.

Highly conserved salt bridge stabilizes rigid signal patch at extracellular loop critical for surface expression of acid-sensing ion channels.

Yang Y, Yu Y, Cheng J, Liu Y, Liu DS, Wang J, Zhu MX, Wang R, Xu TL.

J Biol Chem. 2012 Apr 27;287(18):14443-55. doi: 10.1074/jbc.M111.334250. Epub 2012 Mar 7.

PMID:
22399291
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Nonproton ligand sensing domain is required for paradoxical stimulation of acid-sensing ion channel 3 (ASIC3) channels by amiloride.

Li WG, Yu Y, Huang C, Cao H, Xu TL.

J Biol Chem. 2011 Dec 9;286(49):42635-46. doi: 10.1074/jbc.M111.289058. Epub 2011 Oct 13.

PMID:
21998313
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Annexin II light chain p11 promotes functional expression of acid-sensing ion channel ASIC1a.

Donier E, Rugiero F, Okuse K, Wood JN.

J Biol Chem. 2005 Nov 18;280(46):38666-72. Epub 2005 Sep 16.

PMID:
16169854
[PubMed - indexed for MEDLINE]
Free Article
4.

Subunit-dependent high-affinity zinc inhibition of acid-sensing ion channels.

Chu XP, Wemmie JA, Wang WZ, Zhu XM, Saugstad JA, Price MP, Simon RP, Xiong ZG.

J Neurosci. 2004 Oct 6;24(40):8678-89.

PMID:
15470133
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

A conformation change in the extracellular domain that accompanies desensitization of acid-sensing ion channel (ASIC) 3.

Cushman KA, Marsh-Haffner J, Adelman JP, McCleskey EW.

J Gen Physiol. 2007 Apr;129(4):345-50.

PMID:
17389250
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

ASIC1a-specific modulation of acid-sensing ion channels in mouse cortical neurons by redox reagents.

Chu XP, Close N, Saugstad JA, Xiong ZG.

J Neurosci. 2006 May 17;26(20):5329-39.

PMID:
16707785
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Expression of acid-sensing ion channel 3 (ASIC3) in nucleus pulposus cells of the intervertebral disc is regulated by p75NTR and ERK signaling.

Uchiyama Y, Cheng CC, Danielson KG, Mochida J, Albert TJ, Shapiro IM, Risbud MV.

J Bone Miner Res. 2007 Dec;22(12):1996-2006.

PMID:
17696763
[PubMed - indexed for MEDLINE]
8.

A nonproton ligand sensor in the acid-sensing ion channel.

Yu Y, Chen Z, Li WG, Cao H, Feng EG, Yu F, Liu H, Jiang H, Xu TL.

Neuron. 2010 Oct 6;68(1):61-72. doi: 10.1016/j.neuron.2010.09.001.

PMID:
20920791
[PubMed - indexed for MEDLINE]
Free Article
9.

Atomic level characterization of the nonproton ligand-sensing domain of ASIC3 channels.

Yu Y, Li WG, Chen Z, Cao H, Yang H, Jiang H, Xu TL.

J Biol Chem. 2011 Jul 15;286(28):24996-5006. doi: 10.1074/jbc.M111.239558. Epub 2011 May 17.

PMID:
21586569
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

A kinase-anchoring protein 150 and calcineurin are involved in regulation of acid-sensing ion channels ASIC1a and ASIC2a.

Chai S, Li M, Lan J, Xiong ZG, Saugstad JA, Simon RP.

J Biol Chem. 2007 Aug 3;282(31):22668-77. Epub 2007 Jun 4.

PMID:
17548344
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Acid-sensing ion channels contribute to transduction of extracellular acidosis in rat carotid body glomus cells.

Tan ZY, Lu Y, Whiteis CA, Benson CJ, Chapleau MW, Abboud FM.

Circ Res. 2007 Nov 9;101(10):1009-19. Epub 2007 Sep 13.

PMID:
17872465
[PubMed - indexed for MEDLINE]
Free Article
12.

A combined computational and functional approach identifies new residues involved in pH-dependent gating of ASIC1a.

Liechti LA, Bernèche S, Bargeton B, Iwaszkiewicz J, Roy S, Michielin O, Kellenberger S.

J Biol Chem. 2010 May 21;285(21):16315-29. doi: 10.1074/jbc.M109.092015. Epub 2010 Mar 18.

PMID:
20299463
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Identification of the Ca2+ blocking site of acid-sensing ion channel (ASIC) 1: implications for channel gating.

Paukert M, Babini E, Pusch M, GrĂ¼nder S.

J Gen Physiol. 2004 Oct;124(4):383-94.

PMID:
15452199
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Extracellular spermine exacerbates ischemic neuronal injury through sensitization of ASIC1a channels to extracellular acidosis.

Duan B, Wang YZ, Yang T, Chu XP, Yu Y, Huang Y, Cao H, Hansen J, Simon RP, Zhu MX, Xiong ZG, Xu TL.

J Neurosci. 2011 Feb 9;31(6):2101-12. doi: 10.1523/JNEUROSCI.4351-10.2011.

PMID:
21307247
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Trypsin cleaves acid-sensing ion channel 1a in a domain that is critical for channel gating.

Vukicevic M, Weder G, Boillat A, Boesch A, Kellenberger S.

J Biol Chem. 2006 Jan 13;281(2):714-22. Epub 2005 Nov 9.

PMID:
16282326
[PubMed - indexed for MEDLINE]
Free Article
16.

Subtype-specific modulation of acid-sensing ion channel (ASIC) function by 2-guanidine-4-methylquinazoline.

Alijevic O, Kellenberger S.

J Biol Chem. 2012 Oct 19;287(43):36059-70. doi: 10.1074/jbc.M112.360487. Epub 2012 Sep 4.

PMID:
22948146
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Serotonin facilitates peripheral pain sensitivity in a manner that depends on the nonproton ligand sensing domain of ASIC3 channel.

Wang X, Li WG, Yu Y, Xiao X, Cheng J, Zeng WZ, Peng Z, Xi Zhu M, Xu TL.

J Neurosci. 2013 Mar 6;33(10):4265-79. doi: 10.1523/JNEUROSCI.3376-12.2013.

PMID:
23467344
[PubMed - indexed for MEDLINE]
Free Article
18.

The receptor site of the spider toxin PcTx1 on the proton-gated cation channel ASIC1a.

Salinas M, Rash LD, Baron A, Lambeau G, Escoubas P, Lazdunski M.

J Physiol. 2006 Jan 15;570(Pt 2):339-54. Epub 2005 Nov 10.

PMID:
16284080
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Evaluation of the role of nitric oxide in acid sensing ion channel mediated cell death.

Jetti SK, Swain SM, Majumder S, Chatterjee S, Poornima V, Bera AK.

Nitric Oxide. 2010 Apr 1;22(3):213-9. doi: 10.1016/j.niox.2009.12.006. Epub 2010 Jan 4.

PMID:
20045740
[PubMed - indexed for MEDLINE]
20.

Structural plasticity and dynamic selectivity of acid-sensing ion channel-spider toxin complexes.

Baconguis I, Gouaux E.

Nature. 2012 Sep 20;489(7416):400-5. doi: 10.1038/nature11375. Epub 2012 Jul 29.

PMID:
22842900
[PubMed - indexed for MEDLINE]
Free PMC Article

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