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Results: 1 to 20 of 97

1.

Effects of the HIV protease inhibitor ritonavir on GLUT4 knock-out mice.

Vyas AK, Koster JC, Tzekov A, Hruz PW.

J Biol Chem. 2010 Nov 19;285(47):36395-400. doi: 10.1074/jbc.M110.176321. Epub 2010 Sep 23.

PMID:
20864532
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Adipose-specific overexpression of GLUT4 reverses insulin resistance and diabetes in mice lacking GLUT4 selectively in muscle.

Carvalho E, Kotani K, Peroni OD, Kahn BB.

Am J Physiol Endocrinol Metab. 2005 Oct;289(4):E551-61. Epub 2005 May 31.

PMID:
15928024
[PubMed - indexed for MEDLINE]
Free Article
3.

Normal muscle glucose uptake in mice deficient in muscle GLUT4.

Fam BC, Rose LJ, Sgambellone R, Ruan Z, Proietto J, Andrikopoulos S.

J Endocrinol. 2012 Sep;214(3):313-27. doi: 10.1530/JOE-12-0032. Epub 2012 Jun 26.

PMID:
22736482
[PubMed - indexed for MEDLINE]
Free Article
4.

HIV protease inhibitors that block GLUT4 precipitate acute, decompensated heart failure in a mouse model of dilated cardiomyopathy.

Hruz PW, Yan Q, Struthers H, Jay PY.

FASEB J. 2008 Jul;22(7):2161-7. doi: 10.1096/fj.07-102269. Epub 2008 Feb 6.

PMID:
18256305
[PubMed - indexed for MEDLINE]
Free Article
5.

Activation of the hexosamine signaling pathway in adipose tissue results in decreased serum adiponectin and skeletal muscle insulin resistance.

Hazel M, Cooksey RC, Jones D, Parker G, Neidigh JL, Witherbee B, Gulve EA, McClain DA.

Endocrinology. 2004 May;145(5):2118-28. Epub 2003 Dec 18.

PMID:
14684615
[PubMed - indexed for MEDLINE]
6.

The metabolic effects of lopinavir/ritonavir in HIV-negative men.

Lee GA, Seneviratne T, Noor MA, Lo JC, Schwarz JM, Aweeka FT, Mulligan K, Schambelan M, Grunfeld C.

AIDS. 2004 Mar 5;18(4):641-9.

PMID:
15090769
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

GLUT4 glucose transporter deficiency increases hepatic lipid production and peripheral lipid utilization.

Kotani K, Peroni OD, Minokoshi Y, Boss O, Kahn BB.

J Clin Invest. 2004 Dec;114(11):1666-75.

PMID:
15578099
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

GS-8374, a novel HIV protease inhibitor, does not alter glucose homeostasis in cultured adipocytes or in a healthy-rodent model system.

Hruz PW, Yan Q, Tsai L, Koster J, Xu L, Cihlar T, Callebaut C.

Antimicrob Agents Chemother. 2011 Apr;55(4):1377-82. doi: 10.1128/AAC.01184-10. Epub 2011 Jan 18.

PMID:
21245443
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Targeted disruption of the glucose transporter 4 selectively in muscle causes insulin resistance and glucose intolerance.

Zisman A, Peroni OD, Abel ED, Michael MD, Mauvais-Jarvis F, Lowell BB, Wojtaszewski JF, Hirshman MF, Virkamaki A, Goodyear LJ, Kahn CR, Kahn BB.

Nat Med. 2000 Aug;6(8):924-8.

PMID:
10932232
[PubMed - indexed for MEDLINE]
10.

Deletion of Rab GAP AS160 modifies glucose uptake and GLUT4 translocation in primary skeletal muscles and adipocytes and impairs glucose homeostasis.

Lansey MN, Walker NN, Hargett SR, Stevens JR, Keller SR.

Am J Physiol Endocrinol Metab. 2012 Nov 15;303(10):E1273-86. doi: 10.1152/ajpendo.00316.2012. Epub 2012 Sep 25.

PMID:
23011063
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Amelioration of insulin resistance but not hyperinsulinemia in obese mice overexpressing GLUT4 selectively in skeletal muscle.

Tsao TS, Katz EB, Pommer D, Charron MJ.

Metabolism. 2000 Mar;49(3):340-6.

PMID:
10726912
[PubMed - indexed for MEDLINE]
12.

The farnesoid X receptor modulates adiposity and peripheral insulin sensitivity in mice.

Cariou B, van Harmelen K, Duran-Sandoval D, van Dijk TH, Grefhorst A, Abdelkarim M, Caron S, Torpier G, Fruchart JC, Gonzalez FJ, Kuipers F, Staels B.

J Biol Chem. 2006 Apr 21;281(16):11039-49. Epub 2006 Jan 30.

PMID:
16446356
[PubMed - indexed for MEDLINE]
Free Article
13.

HIV protease inhibitors act as competitive inhibitors of the cytoplasmic glucose binding site of GLUTs with differing affinities for GLUT1 and GLUT4.

Hresko RC, Hruz PW.

PLoS One. 2011;6(9):e25237. doi: 10.1371/journal.pone.0025237. Epub 2011 Sep 23.

PMID:
21966466
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

The protease inhibitor combination lopinavir/ritonavir does not decrease insulin secretion in healthy, HIV-seronegative volunteers.

Pao VY, Lee GA, Taylor S, Aweeka FT, Schwarz JM, Mulligan K, Schambelan M, Grunfeld C.

AIDS. 2010 Jan 16;24(2):265-70. doi: 10.1097/QAD.0b013e328333af1c.

PMID:
19890203
[PubMed - indexed for MEDLINE]
15.

AS160 deficiency causes whole-body insulin resistance via composite effects in multiple tissues.

Wang HY, Ducommun S, Quan C, Xie B, Li M, Wasserman DH, Sakamoto K, Mackintosh C, Chen S.

Biochem J. 2013 Jan 15;449(2):479-89. doi: 10.1042/BJ20120702.

PMID:
23078342
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Peripheral but not hepatic insulin resistance in mice with one disrupted allele of the glucose transporter type 4 (GLUT4) gene.

Rossetti L, Stenbit AE, Chen W, Hu M, Barzilai N, Katz EB, Charron MJ.

J Clin Invest. 1997 Oct 1;100(7):1831-9.

PMID:
9312184
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

HIV protease inhibitors acutely impair glucose-stimulated insulin release.

Koster JC, Remedi MS, Qiu H, Nichols CG, Hruz PW.

Diabetes. 2003 Jul;52(7):1695-700.

PMID:
12829635
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Insulin-sensitizing effect of rosiglitazone (BRL-49653) by regulation of glucose transporters in muscle and fat of Zucker rats.

Kramer D, Shapiro R, Adler A, Bush E, Rondinone CM.

Metabolism. 2001 Nov;50(11):1294-300.

PMID:
11699047
[PubMed - indexed for MEDLINE]
19.

Differential effects of leptin in regulation of tissue glucose utilization in vivo.

Wang JL, Chinookoswong N, Scully S, Qi M, Shi ZQ.

Endocrinology. 1999 May;140(5):2117-24.

PMID:
10218962
[PubMed - indexed for MEDLINE]
20.

Effects of atazanavir/ritonavir and lopinavir/ritonavir on glucose uptake and insulin sensitivity: demonstrable differences in vitro and clinically.

Noor MA, Flint OP, Maa JF, Parker RA.

AIDS. 2006 Sep 11;20(14):1813-21.

PMID:
16954722
[PubMed - indexed for MEDLINE]

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