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Results: 1 to 20 of 109

1.

Actin-bundling protein TRIOBP forms resilient rootlets of hair cell stereocilia essential for hearing.

Kitajiri S, Sakamoto T, Belyantseva IA, Goodyear RJ, Stepanyan R, Fujiwara I, Bird JE, Riazuddin S, Riazuddin S, Ahmed ZM, Hinshaw JE, Sellers J, Bartles JR, Hammer JA 3rd, Richardson GP, Griffith AJ, Frolenkov GI, Friedman TB.

Cell. 2010 May 28;141(5):786-98. doi: 10.1016/j.cell.2010.03.049.

PMID:
20510926
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

R1 motif is the major actin-binding domain of TRIOBP-4.

Bao J, Bielski E, Bachhawat A, Taha D, Gunther LK, Thirumurugan K, Kitajiri S, Sakamoto T.

Biochemistry. 2013 Aug 6;52(31):5256-64. doi: 10.1021/bi400585h. Epub 2013 Jul 22.

PMID:
23789641
[PubMed - indexed for MEDLINE]
3.

The deaf mouse mutant whirler suggests a role for whirlin in actin filament dynamics and stereocilia development.

Mogensen MM, Rzadzinska A, Steel KP.

Cell Motil Cytoskeleton. 2007 Jul;64(7):496-508.

PMID:
17326148
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Correlation of expression of the actin filament-bundling protein espin with stereociliary bundle formation in the developing inner ear.

Li H, Liu H, Balt S, Mann S, Corrales CE, Heller S.

J Comp Neurol. 2004 Jan 1;468(1):125-34.

PMID:
14648695
[PubMed - indexed for MEDLINE]
5.

Whirlin interacts with espin and modulates its actin-regulatory function: an insight into the mechanism of Usher syndrome type II.

Wang L, Zou J, Shen Z, Song E, Yang J.

Hum Mol Genet. 2012 Feb 1;21(3):692-710. doi: 10.1093/hmg/ddr503. Epub 2011 Nov 2.

PMID:
22048959
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Roles of the espin actin-bundling proteins in the morphogenesis and stabilization of hair cell stereocilia revealed in CBA/CaJ congenic jerker mice.

Sekerková G, Richter CP, Bartles JR.

PLoS Genet. 2011 Mar;7(3):e1002032. doi: 10.1371/journal.pgen.1002032. Epub 2011 Mar 24.

PMID:
21455486
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Mutations in a novel isoform of TRIOBP that encodes a filamentous-actin binding protein are responsible for DFNB28 recessive nonsyndromic hearing loss.

Shahin H, Walsh T, Sobe T, Abu Sa'ed J, Abu Rayan A, Lynch ED, Lee MK, Avraham KB, King MC, Kanaan M.

Am J Hum Genet. 2006 Jan;78(1):144-52. Epub 2005 Nov 21.

PMID:
16385458
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Twinfilin 2 regulates actin filament lengths in cochlear stereocilia.

Peng AW, Belyantseva IA, Hsu PD, Friedman TB, Heller S.

J Neurosci. 2009 Dec 2;29(48):15083-8. doi: 10.1523/JNEUROSCI.2782-09.2009.

PMID:
19955359
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

The actin-binding proteins eps8 and gelsolin have complementary roles in regulating the growth and stability of mechanosensory hair bundles of mammalian cochlear outer hair cells.

Olt J, Mburu P, Johnson SL, Parker A, Kuhn S, Bowl M, Marcotti W, Brown SD.

PLoS One. 2014 Jan 27;9(1):e87331. doi: 10.1371/journal.pone.0087331. eCollection 2014.

PMID:
24475274
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Balanced levels of Espin are critical for stereociliary growth and length maintenance.

Rzadzinska A, Schneider M, Noben-Trauth K, Bartles JR, Kachar B.

Cell Motil Cytoskeleton. 2005 Nov;62(3):157-65.

PMID:
16206170
[PubMed - indexed for MEDLINE]
11.

Myosin IIIa boosts elongation of stereocilia by transporting espin 1 to the plus ends of actin filaments.

Salles FT, Merritt RC Jr, Manor U, Dougherty GW, Sousa AD, Moore JE, Yengo CM, Dosé AC, Kachar B.

Nat Cell Biol. 2009 Apr;11(4):443-50. doi: 10.1038/ncb1851. Epub 2009 Mar 15.

PMID:
19287378
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

A Myo6 mutation destroys coordination between the myosin heads, revealing new functions of myosin VI in the stereocilia of mammalian inner ear hair cells.

Hertzano R, Shalit E, Rzadzinska AK, Dror AA, Song L, Ron U, Tan JT, Shitrit AS, Fuchs H, Hasson T, Ben-Tal N, Sweeney HL, de Angelis MH, Steel KP, Avraham KB.

PLoS Genet. 2008 Oct 3;4(10):e1000207. doi: 10.1371/journal.pgen.1000207.

PMID:
18833301
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Espins and the actin cytoskeleton of hair cell stereocilia and sensory cell microvilli.

Sekerková G, Zheng L, Loomis PA, Mugnaini E, Bartles JR.

Cell Mol Life Sci. 2006 Oct;63(19-20):2329-41. Review.

PMID:
16909209
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Mutations of the mouse ELMO domain containing 1 gene (Elmod1) link small GTPase signaling to actin cytoskeleton dynamics in hair cell stereocilia.

Johnson KR, Longo-Guess CM, Gagnon LH.

PLoS One. 2012;7(4):e36074. doi: 10.1371/journal.pone.0036074. Epub 2012 Apr 27.

PMID:
22558334
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Multi-isotope imaging mass spectrometry reveals slow protein turnover in hair-cell stereocilia.

Zhang DS, Piazza V, Perrin BJ, Rzadzinska AK, Poczatek JC, Wang M, Prosser HM, Ervasti JM, Corey DP, Lechene CP.

Nature. 2012 Jan 15;481(7382):520-4. doi: 10.1038/nature10745.

PMID:
22246323
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Wrapping up stereocilia rootlets.

Boutet de Monvel J, Petit C.

Cell. 2010 May 28;141(5):748-50. doi: 10.1016/j.cell.2010.05.022.

PMID:
20510920
[PubMed]
Free Article
17.

The R109H variant of fascin-2, a developmentally regulated actin crosslinker in hair-cell stereocilia, underlies early-onset hearing loss of DBA/2J mice.

Shin JB, Longo-Guess CM, Gagnon LH, Saylor KW, Dumont RA, Spinelli KJ, Pagana JM, Wilmarth PA, David LL, Gillespie PG, Johnson KR.

J Neurosci. 2010 Jul 21;30(29):9683-94. doi: 10.1523/JNEUROSCI.1541-10.2010.

PMID:
20660251
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Eps8 regulates hair bundle length and functional maturation of mammalian auditory hair cells.

Zampini V, Rüttiger L, Johnson SL, Franz C, Furness DN, Waldhaus J, Xiong H, Hackney CM, Holley MC, Offenhauser N, Di Fiore PP, Knipper M, Masetto S, Marcotti W.

PLoS Biol. 2011 Apr;9(4):e1001048. doi: 10.1371/journal.pbio.1001048. Epub 2011 Apr 19.

PMID:
21526224
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Caprice/MISP is a novel F-actin bundling protein critical for actin-based cytoskeletal reorganizations.

Kumeta M, Gilmore JL, Umeshima H, Ishikawa M, Kitajiri S, Horigome T, Kengaku M, Takeyasu K.

Genes Cells. 2014 Apr;19(4):338-49. doi: 10.1111/gtc.12131. Epub 2014 Jan 29.

PMID:
24475924
[PubMed - indexed for MEDLINE]
20.

Absence of plastin 1 causes abnormal maintenance of hair cell stereocilia and a moderate form of hearing loss in mice.

Taylor R, Bullen A, Johnson SL, Grimm-Günter EM, Rivero F, Marcotti W, Forge A, Daudet N.

Hum Mol Genet. 2015 Jan 1;24(1):37-49. doi: 10.1093/hmg/ddu417. Epub 2014 Aug 14.

PMID:
25124451
[PubMed - in process]
Free PMC Article

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