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Results: 1 to 20 of 111

1.

BRCA2 function and the central nervous system.

Frappart PO, McKinnon PJ.

Cell Cycle. 2007 Oct 15;6(20):2453-7. Epub 2007 Jul 23.

PMID:
17786054
[PubMed - indexed for MEDLINE]
Free Article
2.

Therapeutic exploitation of tumor cell defects in homologous recombination.

Powell SN, Kachnic LA.

Anticancer Agents Med Chem. 2008 May;8(4):448-60. Review.

PMID:
18473729
[PubMed - indexed for MEDLINE]
3.

Deficiency in BRCA2 leads to increase in non-conservative homologous recombination.

Larminat F, Germanier M, Papouli E, Defais M.

Oncogene. 2002 Aug 1;21(33):5188-92.

PMID:
12140769
[PubMed - indexed for MEDLINE]
Free Article
4.

Responding to DNA double strand breaks in the nervous system.

Lee Y, McKinnon PJ.

Neuroscience. 2007 Apr 14;145(4):1365-74. Epub 2006 Aug 23. Review.

PMID:
16934412
[PubMed - indexed for MEDLINE]
5.

BRCA2 is required for neurogenesis and suppression of medulloblastoma.

Frappart PO, Lee Y, Lamont J, McKinnon PJ.

EMBO J. 2007 Jun 6;26(11):2732-42. Epub 2007 May 3.

PMID:
17476307
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Lower level of BRCA2 protein in heterozygous mutation carriers is correlated with an increase in DNA double strand breaks and an impaired DSB repair.

Arnold K, Kim MK, Frerk K, Edler L, Savelyeva L, Schmezer P, Wiedemeyer R.

Cancer Lett. 2006 Nov 8;243(1):90-100. Epub 2006 Jan 31.

PMID:
16448746
[PubMed - indexed for MEDLINE]
7.

The relationship between the roles of BRCA genes in DNA repair and cancer predisposition.

Tutt A, Ashworth A.

Trends Mol Med. 2002 Dec;8(12):571-6. Review.

PMID:
12470990
[PubMed - indexed for MEDLINE]
8.

BRCA2: a universal recombinase regulator.

Thorslund T, West SC.

Oncogene. 2007 Dec 10;26(56):7720-30. Review.

PMID:
18066084
[PubMed - indexed for MEDLINE]
9.

Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2.

Xia B, Sheng Q, Nakanishi K, Ohashi A, Wu J, Christ N, Liu X, Jasin M, Couch FJ, Livingston DM.

Mol Cell. 2006 Jun 23;22(6):719-29.

PMID:
16793542
[PubMed - indexed for MEDLINE]
Free Article
10.

Impaired removal of DNA interstrand cross-link in Nijmegen breakage syndrome and Fanconi anemia, but not in BRCA-defective group.

Tsuchida K, Komatsu K.

Cancer Sci. 2008 Nov;99(11):2238-43. doi: 10.1111/j.1349-7006.2008.00915.x. Epub 2008 Sep 1.

PMID:
18771529
[PubMed - indexed for MEDLINE]
11.

Recombination mediator and Rad51 targeting activities of a human BRCA2 polypeptide.

San Filippo J, Chi P, Sehorn MG, Etchin J, Krejci L, Sung P.

J Biol Chem. 2006 Apr 28;281(17):11649-57. Epub 2006 Mar 2.

PMID:
16513631
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Homologous recombination is the principal pathway for the repair of DNA damage induced by tirapazamine in mammalian cells.

Evans JW, Chernikova SB, Kachnic LA, Banath JP, Sordet O, Delahoussaye YM, Treszezamsky A, Chon BH, Feng Z, Gu Y, Wilson WR, Pommier Y, Olive PL, Powell SN, Brown JM.

Cancer Res. 2008 Jan 1;68(1):257-65. doi: 10.1158/0008-5472.CAN-06-4497.

PMID:
18172318
[PubMed - indexed for MEDLINE]
Free Article
13.

The DNA double-strand break response in the nervous system.

Abner CW, McKinnon PJ.

DNA Repair (Amst). 2004 Aug-Sep;3(8-9):1141-7. Review.

PMID:
15279803
[PubMed - indexed for MEDLINE]
14.

Emergence of a DNA-damage response network consisting of Fanconi anaemia and BRCA proteins.

Wang W.

Nat Rev Genet. 2007 Oct;8(10):735-48. Epub 2007 Sep 4. Review.

PMID:
17768402
[PubMed - indexed for MEDLINE]
15.

Strand invasion involving short tract gene conversion is specifically suppressed in BRCA2-deficient hamster cells.

Saleh-Gohari N, Helleday T.

Oncogene. 2004 Dec 2;23(56):9136-41.

PMID:
15480413
[PubMed - indexed for MEDLINE]
16.

DNA repair deficiency and neurodegeneration.

Katyal S, McKinnon PJ.

Cell Cycle. 2007 Oct 1;6(19):2360-5. Epub 2007 Jul 18. Review.

PMID:
17700067
[PubMed - indexed for MEDLINE]
Free Article
17.

Brca2/Xrcc2 dependent HR, but not NHEJ, is required for protection against O(6)-methylguanine triggered apoptosis, DSBs and chromosomal aberrations by a process leading to SCEs.

Roos WP, Nikolova T, Quiros S, Naumann SC, Kiedron O, Zdzienicka MZ, Kaina B.

DNA Repair (Amst). 2009 Jan 1;8(1):72-86. doi: 10.1016/j.dnarep.2008.09.003. Epub 2008 Oct 21.

PMID:
18840549
[PubMed - indexed for MEDLINE]
18.

Analysis of DNA repair and recombination responses in mouse cells depleted for Brca2 by SiRNA.

Lee SA, Baker MD.

DNA Repair (Amst). 2007 Jun 1;6(6):809-17. Epub 2007 Mar 2. Erratum in: DNA Repair (Amst). 2007 Oct 1;6(10):1556.

PMID:
17336596
[PubMed - indexed for MEDLINE]
19.

Cellular functions of the BRCA tumour-suppressor proteins.

Boulton SJ.

Biochem Soc Trans. 2006 Nov;34(Pt 5):633-45. Review.

PMID:
17052168
[PubMed - indexed for MEDLINE]
20.

The role of BRCA2 in replication-coupled DNA interstrand cross-link repair in vitro.

Cipak L, Watanabe N, Bessho T.

Nat Struct Mol Biol. 2006 Aug;13(8):729-33. Epub 2006 Jul 16.

PMID:
16845393
[PubMed - indexed for MEDLINE]

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