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Items: 1 to 20 of 165

1.

Solution structure of mu-conotoxin PIIIA, a preferential inhibitor of persistent tetrodotoxin-sensitive sodium channels.

Nielsen KJ, Watson M, Adams DJ, Hammarström AK, Gage PW, Hill JM, Craik DJ, Thomas L, Adams D, Alewood PF, Lewis RJ.

J Biol Chem. 2002 Jul 26;277(30):27247-55. Epub 2002 May 2.

2.

Isolation and structure-activity of mu-conotoxin TIIIA, a potent inhibitor of tetrodotoxin-sensitive voltage-gated sodium channels.

Lewis RJ, Schroeder CI, Ekberg J, Nielsen KJ, Loughnan M, Thomas L, Adams DA, Drinkwater R, Adams DJ, Alewood PF.

Mol Pharmacol. 2007 Mar;71(3):676-85. Epub 2006 Dec 1.

3.

mu-Conotoxin PIIIA, a new peptide for discriminating among tetrodotoxin-sensitive Na channel subtypes.

Shon KJ, Olivera BM, Watkins M, Jacobsen RB, Gray WR, Floresca CZ, Cruz LJ, Hillyard DR, Brink A, Terlau H, Yoshikami D.

J Neurosci. 1998 Jun 15;18(12):4473-81.

4.
5.

Structural basis for tetrodotoxin-resistant sodium channel binding by mu-conotoxin SmIIIA.

Keizer DW, West PJ, Lee EF, Yoshikami D, Olivera BM, Bulaj G, Norton RS.

J Biol Chem. 2003 Nov 21;278(47):46805-13. Epub 2003 Sep 10.

6.

Structural and functional diversities among mu-conotoxins targeting TTX-resistant sodium channels.

Zhang MM, Fiedler B, Green BR, Catlin P, Watkins M, Garrett JE, Smith BJ, Yoshikami D, Olivera BM, Bulaj G.

Biochemistry. 2006 Mar 21;45(11):3723-32.

PMID:
16533055
7.

A novel conotoxin from Conus striatus, mu-SIIIA, selectively blocking rat tetrodotoxin-resistant sodium channels.

Wang CZ, Zhang H, Jiang H, Lu W, Zhao ZQ, Chi CW.

Toxicon. 2006 Jan;47(1):122-32. Epub 2005 Dec 1.

PMID:
16325217
8.

Neuronally micro-conotoxins from Conus striatus utilize an alpha-helical motif to target mammalian sodium channels.

Schroeder CI, Ekberg J, Nielsen KJ, Adams D, Loughnan ML, Thomas L, Adams DJ, Alewood PF, Lewis RJ.

J Biol Chem. 2008 Aug 1;283(31):21621-8. doi: 10.1074/jbc.M802852200. Epub 2008 Jun 3.

9.

Novel conotoxins from Conus striatus and Conus kinoshitai selectively block TTX-resistant sodium channels.

Bulaj G, West PJ, Garrett JE, Watkins M, Zhang MM, Norton RS, Smith BJ, Yoshikami D, Olivera BM.

Biochemistry. 2005 May 17;44(19):7259-65. Erratum in: Biochemistry. 2006 Mar 7;45(9):3116. Marsh, Maren [corrected to Watkins, Maren].

PMID:
15882064
10.
11.

Structures of muO-conotoxins from Conus marmoreus. I nhibitors of tetrodotoxin (TTX)-sensitive and TTX-resistant sodium channels in mammalian sensory neurons.

Daly NL, Ekberg JA, Thomas L, Adams DJ, Lewis RJ, Craik DJ.

J Biol Chem. 2004 Jun 11;279(24):25774-82. Epub 2004 Mar 24.

12.

Mu-conotoxin SmIIIA, a potent inhibitor of tetrodotoxin-resistant sodium channels in amphibian sympathetic and sensory neurons.

West PJ, Bulaj G, Garrett JE, Olivera BM, Yoshikami D.

Biochemistry. 2002 Dec 24;41(51):15388-93.

PMID:
12484778
14.

Conus geographus toxins that discriminate between neuronal and muscle sodium channels.

Cruz LJ, Gray WR, Olivera BM, Zeikus RD, Kerr L, Yoshikami D, Moczydlowski E.

J Biol Chem. 1985 Aug 5;260(16):9280-8.

15.

Function and solution structure of huwentoxin-IV, a potent neuronal tetrodotoxin (TTX)-sensitive sodium channel antagonist from Chinese bird spider Selenocosmia huwena.

Peng K, Shu Q, Liu Z, Liang S.

J Biol Chem. 2002 Dec 6;277(49):47564-71. Epub 2002 Sep 11. Erratum in: J Biol Chem. 2003 Feb 14;278(7):5489..

16.

Multiple, distributed interactions of μ-conotoxin PIIIA associated with broad targeting among voltage-gated sodium channels.

McArthur JR, Ostroumov V, Al-Sabi A, McMaster D, French RJ.

Biochemistry. 2011 Jan 11;50(1):116-24. Epub 2010 Dec 10.

PMID:
21110521
18.

Pharmacological fractionation of tetrodotoxin-sensitive sodium currents in rat dorsal root ganglion neurons by μ-conotoxins.

Zhang MM, Wilson MJ, Gajewiak J, Rivier JE, Bulaj G, Olivera BM, Yoshikami D.

Br J Pharmacol. 2013 May;169(1):102-14. doi: 10.1111/bph.12119.

19.

N- and C-terminal extensions of μ-conotoxins increase potency and selectivity for neuronal sodium channels.

Schroeder CI, Adams D, Thomas L, Alewood PF, Lewis RJ.

Biopolymers. 2012;98(2):161-5. doi: 10.1002/bip.22032. Epub 2012 Feb 10.

PMID:
22733528
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