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Page 1
SARS-CoV-2 infection induces beta cell transdifferentiation.
Tang X, Uhl S, Zhang T, Xue D, Li B, Vandana JJ, Acklin JA, Bonnycastle LL, Narisu N, Erdos MR, Bram Y, Chandar V, Chong ACN, Lacko LA, Min Z, Lim JK, Borczuk AC, Xiang J, Naji A, Collins FS, Evans T, Liu C, tenOever BR, Schwartz RE, Chen S. Tang X, et al. Cell Metab. 2021 Aug 3;33(8):1577-1591.e7. doi: 10.1016/j.cmet.2021.05.015. Epub 2021 May 19. Cell Metab. 2021. PMID: 34081913 Free PMC article.
A Freshwater Fish-Based Diet Alleviates Liver Steatosis by Modulating Gut Microbiota and Metabolites: A Clinical Randomized Controlled Trial in Chinese Participants With Nonalcoholic Fatty Liver Disease.
He K, Guo LL, Tang H, Peng X, Li J, Feng S, Bie C, Chen W, Li Y, Wang M, Tang S. He K, et al. Am J Gastroenterol. 2022 Oct 1;117(10):1621-1631. doi: 10.14309/ajg.0000000000001885. Epub 2022 Jun 17. Am J Gastroenterol. 2022. PMID: 35973188 Free PMC article. Clinical Trial.
Synergetic protective effect of remote ischemic preconditioning and prolyl 4‑hydroxylase inhibition in ischemic cardiac injury.
Yang J, Xu J, Tao L, Wang S, Xiang H, Tang Y. Yang J, et al. Mol Med Rep. 2022 Mar;25(3):80. doi: 10.3892/mmr.2022.12596. Epub 2022 Jan 14. Mol Med Rep. 2022. PMID: 35029283 Free PMC article.
The present study aimed to investigate the protective effect of RIP, PHD inhibition using dimethyloxalylglycine (DMOG) and their combination on I/R-induced cardiac injury. Rabbits were randomly divided into seven groups: i) Sham; ii) I/R; iii) lung RIP + I/R; iv) thigh RIP …
The present study aimed to investigate the protective effect of RIP, PHD inhibition using dimethyloxalylglycine (DMOG) and their comb …
The MEDEA FAR-EAST Study: Conceptual framework, methods and first findings of a multicenter cross-sectional observational study.
Hoschar S, Pan J, Wang Z, Fang X, Tang X, Shi W, Tu R, Xi P, Che W, Wang H, Li Y, Fritzsche K, Liu X, Ladwig KH, Ma W. Hoschar S, et al. BMC Emerg Med. 2019 May 2;19(1):31. doi: 10.1186/s12873-019-0240-7. BMC Emerg Med. 2019. PMID: 31046724 Free PMC article.
METHODS: Data sources of this multicenter cross-sectional observational study are a standardized bedside interview, a self-administered tailored questionnaire tool and the patient chart. PHD was defined as the main outcome and triangulated at bedside. ...Prehospital delay …
METHODS: Data sources of this multicenter cross-sectional observational study are a standardized bedside interview, a self-administered tail …
Nebulised Isotonic Hydroxychloroquine Aerosols for Potential Treatment of COVID-19.
Tai W, Chow MYT, Chang RYK, Tang P, Gonda I, MacArthur RB, Chan HK, Kwok PCL. Tai W, et al. Pharmaceutics. 2021 Aug 14;13(8):1260. doi: 10.3390/pharmaceutics13081260. Pharmaceutics. 2021. PMID: 34452220 Free PMC article.
As the drug concentration and liquid volume increased, the nebulisation duration increased from 3 to 11 min. The emitted doses ranged from 9.1 to 75.9 mg, depending on the concentration and volume nebulised. ...
As the drug concentration and liquid volume increased, the nebulisation duration increased from 3 to 11 min. The emitted doses ranged …
Role of adiponectin in diabetes myocardial ischemia-reperfusion injury and ischemic postconditioning.
Cao C, Liu HM, Li W, Wu Y, Leng Y, Xue R, Chen R, Tang LH, Sun Q, Xia Z, Tang QZ, Shen DF, Meng QT. Cao C, et al. Acta Cir Bras. 2020 Mar 23;35(1):e202000107. doi: 10.1590/s0102-865020200010000007. eCollection 2020. Acta Cir Bras. 2020. PMID: 32215448 Free PMC article.
We hypothesized that decreased cardiac Adiponectin (APN) is responsible for the loss of diabetic heart sensitivity to IPO cardioprotecton. METHODS: Diabetic rats were subjected to I/R injury (30 min of LAD occlusion followed by 120 min of reperfusion). Myocardial in …
We hypothesized that decreased cardiac Adiponectin (APN) is responsible for the loss of diabetic heart sensitivity to IPO cardioprotecton. M …
Pharmacokinetic Herb-Drug Interactions of Xiang-Sha-Liu-Jun-Zi-Tang and Paclitaxel in Male Sprague Dawley Rats and Its Influence on Enzyme Kinetics in Human Liver Microsomes.
Kapelemera AM, Uang YS, Wang LH, Wu TY, Lee FY, Tai L, Wang CC, Lee CJ. Kapelemera AM, et al. Front Pharmacol. 2022 Apr 5;13:858007. doi: 10.3389/fphar.2022.858007. eCollection 2022. Front Pharmacol. 2022. PMID: 35450043 Free PMC article.
They can be administered before, during, and after chemotherapy. Xiang-Sha-Liu-Jun-Zi Tang (XSLJZT) is a herbal formula commonly used in breast cancer patients. ...However, the half-life was prolonged in all groups from 17.11 min to a maximum of 37.56 min. XS …
They can be administered before, during, and after chemotherapy. Xiang-Sha-Liu-Jun-Zi Tang (XSLJZT) is a herbal formula commonly used …
Clinical Outcomes and Clinico-pathological Correlations in Lupus Nephritis with Kidney Biopsy Showing Thrombotic Microangiopathy.
Li C, Yap DYH, Chan G, Wen YB, Li H, Tang C, Li XM, Li XW, Chan TM. Li C, et al. J Rheumatol. 2019 Nov;46(11):1478-1484. doi: 10.3899/jrheum.180773. Epub 2019 Mar 15. J Rheumatol. 2019. PMID: 30877215

TMA was associated with a higher prevalence of anti-Ro (45.8% vs 18.8%; p = 0.016), higher Systemic Lupus Erythematosus Disease Activity Index scores (21.4 8.5 vs 10.8 2.3; p < 0.001), lower estimated glomerular filtration rate (eGFR; 16.8 11.7 ml/min vs 77.8 28.6 ml/

…
TMA was associated with a higher prevalence of anti-Ro (45.8% vs 18.8%; p = 0.016), higher Systemic Lupus Erythematosus Disease Activity Ind …
The electronic medical record management systems may improve monitoring and control of disease activity in patients with ankylosing spondylitis.
Huang PJ, Chen YH, Huang WN, Chen YM, Lai KL, Hsieh TY, Hung WT, Lin CT, Tseng CW, Tang KT, Chou YY, Wu YD, Huang CY, Hsieh CW, Chen YJ, Liao YW, Liu YT, Chen HH. Huang PJ, et al. Sci Rep. 2023 Mar 9;13(1):3957. doi: 10.1038/s41598-023-30848-w. Sci Rep. 2023. PMID: 36894589 Free PMC article.

The average visit time was reduced within 1 year after ASDAS assessment (6.4 (8.5, 11.2) vs. 6.3 (8.3, 10.8) min, p = 0.073), especially among patients whose with an inactive disease activity was < 1.3 (ASDAS C-reactive protein (CRP) 6.7 (8.8, 11.1) vs. 6.1 (8.0, 10.3)

…
The average visit time was reduced within 1 year after ASDAS assessment (6.4 (8.5, 11.2) vs. 6.3 (8.3, 10.8) min, p = 0.073), especia …
Profile of patients at admission into an inpatient stroke rehabilitation programme: cardiorespiratory fitness and functional characteristics.
Brooks D, Tang A, Sibley KM, McIlroy WE. Brooks D, et al. Physiother Can. 2008 Spring;60(2):171-9. doi: 10.3138/physio.60.2.171. Epub 2008 Oct 10. Physiother Can. 2008. PMID: 20145780 Free PMC article.
Average VO(2)peak was less than half the value expected in age-matched healthy individuals at 11.1 (3.1) ml/kg/min. The associations between VO(2)peak and FIM, NIHSS, and COVS were weak (r = 0.25, -0.12, and 0.26 respectively, p = 0.12, 0.46, and 0.10 respectively). ...
Average VO(2)peak was less than half the value expected in age-matched healthy individuals at 11.1 (3.1) ml/kg/min. The associations …