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A prognostic algorithm including a modified version of MD Anderson Cancer Center (MDACC) score predicts time to first treatment of patients with clinical monoclonal lymphocytosis (cMBL)/Rai stage 0 chronic lymphocytic leukemia (CLL).
Int J Hematol. 2014 Sep;100(3):290-5. doi: 10.1007/s12185-014-1634-7. Epub 2014 Jul 27.
Int J Hematol. 2014.
PMID: 25064370
Clinical Trial.
We propose an algorithm based on a slightly modified version of MD Anderson Cancer Center (MDACC) score (i.e., mutational status of IgVH, LDH, presence of high-risk FISH abnormalities), beta2-microglobulin and separation of clinical monoclonal B-cell lymphocytosis (cMBL) f …
We propose an algorithm based on a slightly modified version of MD Anderson Cancer Center (MDACC) score (i.e., mutational status of I …
Unavailability of thymidine kinase does not preclude the use of German comprehensive prognostic index: results of an external validation analysis in early chronic lymphocytic leukemia and comparison with MD Anderson Cancer Center model.
Molica S, Giannarelli D, Mirabelli R, Levato L, Russo A, Linardi M, Gentile M, Morabito F.
Molica S, et al. Among authors: mirabelli r.
Eur J Haematol. 2016 Jan;96(1):72-7. doi: 10.1111/ejh.12550. Epub 2015 Apr 18.
Eur J Haematol. 2016.
PMID: 25819739
Clinical Trial.
This stratification translated into a significant difference in the TTFT [HR = 4.21; 95% C.I. (2.71-6.53); P < 0.0001]. Also the 2007 MD Anderson Cancer Center (MDACC) score, barely based on traditional clinical parameters, showed comparable reliability [HR = 2.73; 95%
…This stratification translated into a significant difference in the TTFT [HR = 4.21; 95% C.I. (2.71-6.53); P < 0.0001]. Also the 2007
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