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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1937 2
1938 2
1940 1
1941 1
1942 2
1943 3
1944 1
1945 29
1946 59
1947 83
1948 109
1949 95
1950 288
1951 225
1952 165
1953 148
1954 132
1955 132
1956 167
1957 185
1958 177
1959 208
1960 235
1961 273
1962 307
1963 539
1964 675
1965 537
1966 478
1967 616
1968 741
1969 870
1970 855
1971 943
1972 1147
1973 1322
1974 1562
1975 1773
1976 1631
1977 1771
1978 1731
1979 1911
1980 1975
1981 2009
1982 1952
1983 2102
1984 2189
1985 2148
1986 2241
1987 2259
1988 2139
1989 2257
1990 2327
1991 2253
1992 2251
1993 2223
1994 2068
1995 2237
1996 2173
1997 2272
1998 2284
1999 2474
2000 2729
2001 2899
2002 3013
2003 3084
2004 3114
2005 3368
2006 3495
2007 3440
2008 3591
2009 3423
2010 3459
2011 3461
2012 3500
2013 3416
2014 3432
2015 3348
2016 3221
2017 3140
2018 3137
2019 3034
2020 3199
2021 3171
2022 2922
2023 2721
2024 1095

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134,593 results

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Page 1
Estradiol valerate/dienogest.
Wellington K, Perry CM. Wellington K, et al. Drugs. 2002;62(3):491-504; discussion 505-6. doi: 10.2165/00003495-200262030-00006. Drugs. 2002. PMID: 11827562 Review.
The number of days without any type of bleeding was lowest in patients treated with estradiol valerate 2mg/dienogest 2mg (8.7 days), and highest in the estradiol valerate 2mg/ dienogest 3mg group (12.1 days). ...Endometrial biopsy results were similar …
The number of days without any type of bleeding was lowest in patients treated with estradiol valerate 2mg/dienogest 2mg (8.7 …
Estradiol valerate/dienogest: a novel oral contraceptive.
Whalen KL, Rose R. Whalen KL, et al. Ann Pharmacother. 2011 Oct;45(10):1256-61. doi: 10.1345/aph.1Q216. Epub 2011 Sep 13. Ann Pharmacother. 2011. PMID: 21917554 Review.
OBJECTIVE: To review the pharmacology, pharmacokinetics, efficacy, and safety of the new oral contraceptive estradiol valerate/dienogest. DATA SOURCES: Searches of PubMed (1966-July 2011) and International Pharmaceutical Abstracts (1970-July 2011) were conducted usi …
OBJECTIVE: To review the pharmacology, pharmacokinetics, efficacy, and safety of the new oral contraceptive estradiol valerate …
Estradiol valerate/dienogest: in oral contraception.
Hoy SM, Scott LJ. Hoy SM, et al. Drugs. 2009 Aug 20;69(12):1635-46. doi: 10.2165/11202820-000000000-00000. Drugs. 2009. PMID: 19678714 Review.
Estradiol valerate/dienogest is an oral contraceptive for women that combines the natural estrogen estradiol with the 19-nortestosterone derivative dienogest in a four-phasic formulation. ...This pooled analysis of three studies excluded those pregnancies occ …
Estradiol valerate/dienogest is an oral contraceptive for women that combines the natural estrogen estradiol with the 1 …
Estradiol valerate/dienogest: a novel combined oral contraceptive.
Borgelt LM, Martell CW. Borgelt LM, et al. Clin Ther. 2012 Jan;34(1):37-55. doi: 10.1016/j.clinthera.2011.11.006. Epub 2011 Dec 14. Clin Ther. 2012. PMID: 22169052 Review.
BACKGROUND: Estradiol valerate/dienogest (E2V/DNG) is a combined oral contraceptive (COC) with 2 new hormonal entities and a unique 4-phasic dosing regimen indicated for women to prevent pregnancy. ...METHODS: MEDLINE (1966-June 2011) and EMBASE (1966-June 2011) wer …
BACKGROUND: Estradiol valerate/dienogest (E2V/DNG) is a combined oral contraceptive (COC) with 2 new hormonal entities and a u …
Pharmacology of estradiol valerate/dienogest.
Teichmann A. Teichmann A. Climacteric. 2003 Aug;6 Suppl 2:17-23. Climacteric. 2003. PMID: 14669840 Review.
The particular features of the pharmacology of a new continuous regimen for hormone replacement therapy containing 2 mg estradiol valerate (E2V) and 2 mg dienogest (DNG) (Climodien, Schering AG, Berlin, Germany) depend largely on its progestogenic component. ...
The particular features of the pharmacology of a new continuous regimen for hormone replacement therapy containing 2 mg estradiol …
Contraception containing estradiol valerate and dienogest--advantages, adherence and user satisfaction.
Graziottin A. Graziottin A. Minerva Ginecol. 2014 Oct;66(5):479-95. Minerva Ginecol. 2014. PMID: 25245997 Review.
The contraceptive pill containing estradiol valerate and dienogest meets women's requests for: a more natural contraceptive, that is reliable and easy to use, with positive cosmetic effects; less intense and shorter bleeding, reduced anaemia and increased vital ener …
The contraceptive pill containing estradiol valerate and dienogest meets women's requests for: a more natural contraceptive, t …
Estradiol Valerate vs Ethinylestradiol in Combined Oral Contraceptives: Effects on the Pituitary-Ovarian Axis.
Haverinen A, Luiro K, Kangasniemi MH, Piltonen TT, Hustad S, Heikinheimo O, Tapanainen JS. Haverinen A, et al. J Clin Endocrinol Metab. 2022 Jun 16;107(7):e3008-e3017. doi: 10.1210/clinem/dgac150. J Clin Endocrinol Metab. 2022. PMID: 35279718 Clinical Trial.
CONTEXT: Limited studies have compared the effects of combined oral contraceptives (COCs) containing natural estrogens and synthetic ethinylestradiol (EE) on reproductive hormones. OBJECTIVE: To compare estradiol valerate (EV) + dienogest (DNG), EE + DNG, and DNG al …
CONTEXT: Limited studies have compared the effects of combined oral contraceptives (COCs) containing natural estrogens and synthetic ethinyl …
Evaluation of a new estradiol oral contraceptive: estradiol valerate and dienogest.
Jensen JT. Jensen JT. Expert Opin Pharmacother. 2010 May;11(7):1147-57. doi: 10.1517/14656561003724713. Expert Opin Pharmacother. 2010. PMID: 20367275 Review.
IMPORTANCE OF THE FIELD: Since ethinyl estradiol is a potent activator of hepatic enzymes, the use of natural estradiol (E2) has been studied; but, until recently, bleeding control has hampered development of an E2 pill. AREAS COVERED IN THIS REVIEW: A historical re …
IMPORTANCE OF THE FIELD: Since ethinyl estradiol is a potent activator of hepatic enzymes, the use of natural estradiol (E2) h …
Ethinyl estradiol vs estradiol valerate in combined oral contraceptives - Effect on glucose tolerance: A randomized, controlled clinical trial.
Haverinen A, Kangasniemi M, Luiro K, Piltonen T, Heikinheimo O, Tapanainen JS. Haverinen A, et al. Contraception. 2021 Jan;103(1):53-59. doi: 10.1016/j.contraception.2020.10.014. Epub 2020 Oct 21. Contraception. 2021. PMID: 33098852 Clinical Trial.
OBJECTIVE: To compare the effects of two formulations of combined oral contraceptives (COCs), estradiol valerate (EV) and ethinyl estradiol (EE) combined with dienogest (DNG), and DNG-only, on glucose tolerance. ...CONCLUSION: We found no clinically significa …
OBJECTIVE: To compare the effects of two formulations of combined oral contraceptives (COCs), estradiol valerate (EV) and ethi …
An overview of the development of combined oral contraceptives containing estradiol: focus on estradiol valerate/dienogest.
Fruzzetti F, Trémollieres F, Bitzer J. Fruzzetti F, et al. Gynecol Endocrinol. 2012 May;28(5):400-8. doi: 10.3109/09513590.2012.662547. Epub 2012 Apr 2. Gynecol Endocrinol. 2012. PMID: 22468839 Free PMC article. Review.
Natural estrogens such as estradiol (E(2)) or its valerate ester (E(2)V) offer an alternative to ethinyl estradiol (EE). ...
Natural estrogens such as estradiol (E(2)) or its valerate ester (E(2)V) offer an alternative to ethinyl estradiol (EE) …
134,593 results
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