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Vascularized Tumor Spheroid-on-a-Chip Model Verifies Synergistic Vasoprotective and Chemotherapeutic Effects.
Hu Z, Cao Y, Galan EA, Hao L, Zhao H, Tang J, Sang G, Wang H, Xu B, Ma S. Hu Z, et al. Among authors: xu b. ACS Biomater Sci Eng. 2022 Mar 14;8(3):1215-1225. doi: 10.1021/acsbiomaterials.1c01099. Epub 2022 Feb 15. ACS Biomater Sci Eng. 2022. PMID: 35167260
Prolyl hydroxylases (PHD) inhibitors have been observed to improve drug distribution in mice tumors via blood vessel normalization, increasing the effectiveness of chemotherapy. ...Here, we used a perfusable vascularized tumor spheroid-on-a-chip to simulate the tumor micro …
Prolyl hydroxylases (PHD) inhibitors have been observed to improve drug distribution in mice tumors via blood vessel normalization, i …