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1980 23
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Acemetacin monohydrate.
Gelbrich T, Haddow MF, Griesser UJ. Gelbrich T, et al. Acta Crystallogr C. 2007 Aug;63(Pt 8):o451-3. doi: 10.1107/S0108270107030065. Epub 2007 Jul 5. Acta Crystallogr C. 2007. PMID: 17675694
The structure of the title compound (systematic name: 2-{2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetoxy}acetic acid monohydrate, C(21)H(18)ClNO(6).H(2)O) contains one-dimensional infinite hydrogen-bonded chains. Molecules of acemetacin, a nonsteroidal anti …
The structure of the title compound (systematic name: 2-{2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetoxy}acetic acid monohyd …
Non-steroidal anti-inflammatory drugs (NSAIDs), pain and aging: Adjusting prescription to patient features.
Ribeiro H, Rodrigues I, Napoleão L, Lira L, Marques D, Veríssimo M, Andrade JP, Dourado M. Ribeiro H, et al. Biomed Pharmacother. 2022 Jun;150:112958. doi: 10.1016/j.biopha.2022.112958. Epub 2022 Apr 19. Biomed Pharmacother. 2022. PMID: 35453005 Free article. Review.
A narrative review of papers published from January 2011 to December 2021, after a literature search in selected databases using the terms "pharmacokinetics", "ibuprofen", "diclofenac", "acemetacin", "naproxen", "etodolac" and "etoricoxib" was performed. ...
A narrative review of papers published from January 2011 to December 2021, after a literature search in selected databases using the terms " …
Acemetacin-phosphatidylcholine interactions are determined by the drug ionization state.
Pereira-Leite C , Nunes C , Grahl D , Bozelli JC , Schreier S , Kamma-Lorger CS , Cuccovia IM , Reis S . Pereira-Leite C , et al. Phys Chem Chem Phys. 2018 May 30;20(21):14398-14409. doi: 10.1039/c8cp01698d. Phys Chem Chem Phys. 2018. PMID: 29770409
The acemetacin-DMPC interactions were clearly pH-dependent. The neutral (protonated) form of acemetacin had more affinity for the DMPC bilayer than the negatively charged form. ...These results support the hypothesis that acemetacin-induced gastric toxicity m …
The acemetacin-DMPC interactions were clearly pH-dependent. The neutral (protonated) form of acemetacin had more affinity for …
Radioiodinated acemetacin loaded niosomes as a dual anticancer therapy.
Shewaiter MA, Selim AA, Moustafa YM, Gad S, Rashed HM. Shewaiter MA, et al. Int J Pharm. 2022 Nov 25;628:122345. doi: 10.1016/j.ijpharm.2022.122345. Epub 2022 Oct 28. Int J Pharm. 2022. PMID: 36349611
A niosomal formula of acemetacin was developed to improve its tumor targeting and radio-kinetic evaluation was performed using (131)I. ...
A niosomal formula of acemetacin was developed to improve its tumor targeting and radio-kinetic evaluation was performed using (131)I …
Single dose oral acemetacin for acute postoperative pain in adults.
Moore RA, Derry S, McQuay HJ. Moore RA, et al. Cochrane Database Syst Rev. 2009 Jul 8;2009(3):CD007589. doi: 10.1002/14651858.CD007589.pub2. Cochrane Database Syst Rev. 2009. PMID: 19588437 Free PMC article. Review.
BACKGROUND: Acemetacin is a non-steroidal anti-inflammatory drug (NSAID) licensed for use in rheumatic disease and other musculoskeletal disorders in the UK, and widely available in other countries worldwide. ...AUTHORS' CONCLUSIONS: In the absence of randomised evidence o …
BACKGROUND: Acemetacin is a non-steroidal anti-inflammatory drug (NSAID) licensed for use in rheumatic disease and other musculoskele …
Acemetacin-induced fixed drug eruption.
Cebeci F, Yaşar Ş, Aytekin S, Güneş P. Cebeci F, et al. Indian J Pharmacol. 2016 Mar-Apr;48(2):219-20. doi: 10.4103/0253-7613.178824. Indian J Pharmacol. 2016. PMID: 27114641 Free PMC article.
Fixed drug eruption (FDE) is an adverse effect observed with various drugs such as nonsteroidal anti-inflammatory drugs (NSAIDs) and various antibiotics. Acemetacin, a prodrug of indomethacin, is an NSAID licensed for use in rheumatic disease and other musculoskeletal diso …
Fixed drug eruption (FDE) is an adverse effect observed with various drugs such as nonsteroidal anti-inflammatory drugs (NSAIDs) and various …
Acemetacin antinociceptive mechanism is not related to NO or K+ channel pathways.
Gil-Flores M, Ortiz MI, Castañeda-Hernández G, Chávez-Piña AE. Gil-Flores M, et al. Methods Find Exp Clin Pharmacol. 2010 Mar;32(2):101-5. doi: 10.1358/mf.2010.32.2.1423883. Methods Find Exp Clin Pharmacol. 2010. PMID: 20401346 Free article.
The antinociceptive effect of acemetacin or indomethacin was not significantly different when pretreatment with L-NAME, glibenclamide, apamin or charybdotoxin was done. The antihyperalgesic and antiinflammatory effects were also similar for both indomethacin and acemeta …
The antinociceptive effect of acemetacin or indomethacin was not significantly different when pretreatment with L-NAME, glibenclamide …
Acemetacin cocrystal structures by powder X-ray diffraction.
Bolla G, Chernyshev V, Nangia A. Bolla G, et al. IUCrJ. 2017 Mar 8;4(Pt 3):206-214. doi: 10.1107/S2052252517002305. eCollection 2017 May 1. IUCrJ. 2017. PMID: 28512568 Free PMC article.
Cocrystals of acemetacin drug (ACM) with nicotinamide (NAM), p-aminobenzoic acid (PABA), valerolactam (VLM) and 2-pyridone (2HP) were prepared by melt crystallization and their X-ray crystal structures determined by high-resolution powder X-ray diffraction. The powerful te …
Cocrystals of acemetacin drug (ACM) with nicotinamide (NAM), p-aminobenzoic acid (PABA), valerolactam (VLM) and 2-pyridone (2HP) were …
Airborne allergic contact dermatitis due to acemetacin.
Machado Á, Ferreira S, Lobo I, Sanches M, Selores M. Machado Á, et al. Contact Dermatitis. 2020 Feb;82(2):133-134. doi: 10.1111/cod.13418. Epub 2019 Nov 5. Contact Dermatitis. 2020. PMID: 31617597 No abstract available.
[Acemetacin, a Prodrug of Indomethacin, Is Effective for Treatment of Hemicrania Continua: A Japanese Case Report].
Kikui S, Sugiyama H, Miyahara J, Ota K, Danno D, Kashiwaya Y, Takeshima T. Kikui S, et al. Brain Nerve. 2022 Oct;74(10):1215-1219. doi: 10.11477/mf.1416202213. Brain Nerve. 2022. PMID: 36198648 Japanese.
Because production of the oral indomethacin was discontinued in April 2020, acemetacin, a prodrug of indomethacin, was administered (90 mg/day) and gradually increased to 180 mg/day over 2 months. No recurrence of HC developed. No reports of HC treated with acemetacin …
Because production of the oral indomethacin was discontinued in April 2020, acemetacin, a prodrug of indomethacin, was administered ( …
150 results