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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1962 1
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1966 22
1967 33
1968 38
1969 49
1970 42
1971 37
1972 31
1973 28
1974 28
1975 20
1976 11
1977 14
1978 7
1979 11
1980 14
1981 10
1982 14
1983 9
1984 13
1985 7
1986 11
1987 17
1988 8
1989 11
1990 6
1991 7
1992 11
1993 5
1994 10
1995 8
1996 12
1997 6
1998 6
1999 9
2000 7
2001 3
2002 2
2003 5
2004 12
2005 4
2006 6
2007 8
2008 7
2009 1
2010 3
2011 6
2012 5
2013 11
2014 5
2015 4
2016 6
2017 5
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2019 5
2020 8
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2022 7
2023 3
2024 1

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738 results

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Page 1
Glucocorticoids, Cyclosporine, Azathioprine, Chlorambucil, and Mycophenolate in Dogs and Cats: Clinical Uses, Pharmacology, and Side Effects.
Viviano KR. Viviano KR. Vet Clin North Am Small Anim Pract. 2022 May;52(3):797-817. doi: 10.1016/j.cvsm.2022.01.009. Epub 2022 Apr 1. Vet Clin North Am Small Anim Pract. 2022. PMID: 35379498 Review.
The treatment of immune-mediated disease in dogs and cats continues to evolve as new therapies are adapted from human medicine. Glucocorticoids remain the first-line treatment followed by second-line therapies including cyclosporine, azathioprine (dogs), chlo …
The treatment of immune-mediated disease in dogs and cats continues to evolve as new therapies are adapted from human medicine. Gluco …
Effects of azathioprine, 6-mercaptopurine, and 6-thioguanine on canine primary hepatocytes.
LaDuke KE, Ehling S, Cullen JM, Bäumer W. LaDuke KE, et al. Am J Vet Res. 2015 Jul;76(7):649-55. doi: 10.2460/ajvr.76.7.649. Am J Vet Res. 2015. PMID: 26111096 Free article.
OBJECTIVE: To investigate the cytotoxic effects of azathioprine, 6-mercaptopurine, and 6-thioguanine on canine hepatocytes. SAMPLE: Commercially available cryopreserved canine primary hepatocytes. PROCEDURES: The study consisted of 2 trials. ...
OBJECTIVE: To investigate the cytotoxic effects of azathioprine, 6-mercaptopurine, and 6-thioguanine on canine hepatocytes. SA …
Comparison of a chlorambucil-prednisolone combination with an azathioprine-prednisolone combination for treatment of chronic enteropathy with concurrent protein-losing enteropathy in dogs: 27 cases (2007-2010).
Dandrieux JR, Noble PJ, Scase TJ, Cripps PJ, German AJ. Dandrieux JR, et al. J Am Vet Med Assoc. 2013 Jun 15;242(12):1705-14. doi: 10.2460/javma.242.12.1705. J Am Vet Med Assoc. 2013. PMID: 23725434 Free article.
OBJECTIVE: To compare treatment protocols for chronic enteropathy and concurrent protein-losing enteropathy that used prednisolone in conjunction with either azathioprine or chlorambucil in dogs. DESIGN: Retrospective case series. ...Dogs received either an …
OBJECTIVE: To compare treatment protocols for chronic enteropathy and concurrent protein-losing enteropathy that used prednisolone in conjun …
Combination therapy with azathioprine, cyclosporine and ketoconazole in a dog with concurrent pemphigus foliaceus and hyperadrenocorticism - Case report.
Yun T, Koo Y, Kim S, Kim H, Kim S, Kang JH, Yang MP, Kang BT. Yun T, et al. Acta Vet Hung. 2020 Sep 30;68(3):251-256. doi: 10.1556/004.2020.00047. Acta Vet Hung. 2020. PMID: 33221735
A 10-year-old, spayed female Shih Tzu dog presented with a history of progressive erythema and multiple crusts developing 85 days previously. ...To the best of our knowledge, this is the first case report describing concurrent PF and HAC in a dog. Combination therap …
A 10-year-old, spayed female Shih Tzu dog presented with a history of progressive erythema and multiple crusts developing 85 days pre …
In-vitro immunosuppression of canine T-lymphocyte-specific proliferation with dexamethasone, cyclosporine, and the active metabolites of azathioprine and leflunomide in a flow-cytometric assay.
Nafe LA, Dodam JR, Reinero CR. Nafe LA, et al. Can J Vet Res. 2014 Jul;78(3):168-75. Can J Vet Res. 2014. PMID: 24982547 Free PMC article.
A high rate of mortality, expense, and complications of immunosuppressive therapy in dogs underscores the need for optimization of drug dosing. The purpose of this study was to determine, using a flow-cytometric assay, the 50% T-cell inhibitory concentration (IC50) of dexa …
A high rate of mortality, expense, and complications of immunosuppressive therapy in dogs underscores the need for optimization of dr …
Combination of Prednisolone and Azathioprine for Steroid-Responsive Meningitis-Arteritis Treatment in Dogs.
Giraud L, Girod M, Cauzinille L. Giraud L, et al. J Am Anim Hosp Assoc. 2021 Jan 1;57(1):1-7. doi: 10.5326/JAAHA-MS-7019. J Am Anim Hosp Assoc. 2021. PMID: 33260200
The objective of this retrospective study was to evaluate the efficacy, tolerability, and occurrence of relapse for the combination of prednisolone and azathioprine. All dogs received azathioprine 2 mg/kg q 24 hr for 1 mo and then 2 mg/kg every other day for …
The objective of this retrospective study was to evaluate the efficacy, tolerability, and occurrence of relapse for the combination of predn …
Prevalence of hepatotoxicity and myelosuppression with alternate day use of azathioprine and glucocorticoids for treatment of dermatological conditions in dogs.
Eberhardy AC, Heinrich NA, McFadden RA, Reiter LV. Eberhardy AC, et al. Vet Dermatol. 2022 Dec;33(6):503-508. doi: 10.1111/vde.13115. Epub 2022 Aug 24. Vet Dermatol. 2022. PMID: 36000613
BACKGROUND: The use of azathioprine (AZA) in dogs is limited by the potential for hepatotoxicity and myelosuppression. ...The other dog (AZA dose 2.3 mg/kg EOD) had a 30-fold increase in ALT. Azathioprine was not associated with thrombocytopenia, anaem …
BACKGROUND: The use of azathioprine (AZA) in dogs is limited by the potential for hepatotoxicity and myelosuppression. ...The …
Azathioprine and acute pancreatitis: studies with an isolated perfused canine pancreas.
Broe PJ, Cameron JL. Broe PJ, et al. J Surg Res. 1983 Feb;34(2):159-63. doi: 10.1016/0022-4804(83)90055-0. J Surg Res. 1983. PMID: 6185763
In an effort to evaluate the effects of azathioprine on the pancreas, the isolated ex vivo perfused canine pancreas model was used. ...These preliminary studies demonstrate that azathioprine has marked effect on pancreatic function in this model....
In an effort to evaluate the effects of azathioprine on the pancreas, the isolated ex vivo perfused canine pancreas model was …
Short-term effect of cyclophosphamide and azathioprine on selected aspects of the canine blastogenic response.
Ogilvie GK, Felsburg PJ, Harris CW. Ogilvie GK, et al. Vet Immunol Immunopathol. 1988 Mar;18(2):119-27. doi: 10.1016/0165-2427(88)90054-2. Vet Immunol Immunopathol. 1988. PMID: 3388759
The short-term, in vitro responses of canine peripheral blood lymphocytes to mitogenic stimulation and serum immunoglobulin concentrations were evaluated following treatment with currently recommended doses of cyclophosphamide and azathioprine. ...Serum immunoglobul …
The short-term, in vitro responses of canine peripheral blood lymphocytes to mitogenic stimulation and serum immunoglobulin concentra …
The effects of prednisone and azathioprine on circulating immunoglobulin levels and lymphocyte subpopulations in normal dogs.
Rinkardt NE, Kruth SA, Kaushik A. Rinkardt NE, et al. Can J Vet Res. 1999 Jan;63(1):18-24. Can J Vet Res. 1999. PMID: 9918329 Free PMC article.
This study investigates serum immunoglobulin (SIg) levels and lymphocyte subpopulations in normal dogs in response to putative immunosuppressive doses of prednisone and/or azathioprine. ...Lymphocyte subsets were quantified using flow cytometry. Azathioprine- …
This study investigates serum immunoglobulin (SIg) levels and lymphocyte subpopulations in normal dogs in response to putative immuno …
738 results