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Isolation and characterization of radiation hybrids for human chromosome 12.
Höglund M, Sidén T, Aman P, Mandahl N, Mitelman F. Höglund M, et al. Cytogenet Cell Genet. 1995;69(3-4):240-5. doi: 10.1159/000133973. Cytogenet Cell Genet. 1995. PMID: 7698022
We have used an irradiation and fusion procedure to generate somatic cell hybrids that maintain fragments of human chromosome 12. ...FISH analysis, using human Cot1 DNA as a probe, revealed the presence of 1-2 fragments in 11 out of 12 hybrids. ...
We have used an irradiation and fusion procedure to generate somatic cell hybrids that maintain fragments of human chromosome …
Plasma membrane calcium ATPase regulates bone mass by fine-tuning osteoclast differentiation and survival.
Kim HJ, Prasad V, Hyung SW, Lee ZH, Lee SW, Bhargava A, Pearce D, Lee Y, Kim HH. Kim HJ, et al. J Cell Biol. 2012 Dec 24;199(7):1145-58. doi: 10.1083/jcb.201204067. J Cell Biol. 2012. PMID: 23266958 Free PMC article.
PMCA4 also had an anti-osteoclastogenic effect by reducing NO, which facilitates preosteoclast fusion. In addition to their role in immature cells, increased expression of PMCAs in mature osteoclasts prevented osteoclast apoptosis both in vitro and in vivo. ...Thus, our re …
PMCA4 also had an anti-osteoclastogenic effect by reducing NO, which facilitates preosteoclast fusion. In addition to their role in i …
Hyperactivation of the human plasma membrane Ca2+ pump PMCA h4xb by mutation of Glu99 to Lys.
Mazzitelli LR, Adamo HP. Mazzitelli LR, et al. J Biol Chem. 2014 Apr 11;289(15):10761-10768. doi: 10.1074/jbc.M113.535583. Epub 2014 Feb 28. J Biol Chem. 2014. PMID: 24584935 Free PMC article.
Autoinhibition is relieved by the binding of Ca(2+)-calmodulin to the calmodulin-binding autoinhibitory sequence, which in the human PMCA is located in the C-terminal segment and results in a PMCA of high maximal velocity of transport and high affinity for Ca(2+). Autoinhi …
Autoinhibition is relieved by the binding of Ca(2+)-calmodulin to the calmodulin-binding autoinhibitory sequence, which in the human …