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Genetic variation of YWHAE gene-"Switch" of disease control.
Jin X, Dai M, Zhou Y. Jin X, et al. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2022 Jan 28;47(1):101-108. doi: 10.11817/j.issn.1672-7347.2022.210394. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2022. PMID: 35545369 Free PMC article. Chinese, English.
To understand the relationship between YWHAE, NUTM2A, and NUTM2B gene rearrangement/fusion and malignant tumor, YWHAE-FAM22 fusion gene/translocation and tumor, YWHAE gene polymorphism and mental illness, as well as the relationship betwe …
To understand the relationship between YWHAE, NUTM2A, and NUTM2B gene rearrangement/fusion and malignant tumor, YWHA
An Unusual Case of YWHAE-NUTM2A/B Endometrial Stromal Sarcoma With Confinement to the Endometrium and Lack of High-Grade Morphology.
Attygalle AD, Vroobel K, Wren D, Barton DP, Hazell SJ, Cin PD, Koelble K, McCluggage WG. Attygalle AD, et al. Int J Gynecol Pathol. 2017 Mar;36(2):165-171. doi: 10.1097/PGP.0000000000000286. Int J Gynecol Pathol. 2017. PMID: 27171540
Endometrial stromal sarcoma (ESS) characterized by YWHAE-NUTM2A/B genetic fusion is a recently recognized entity that is classified as a high-grade (HG) ESS in the 2014 World Health Organization Classification. ...The initial hysteroscopic biopsy showed a cyc …
Endometrial stromal sarcoma (ESS) characterized by YWHAE-NUTM2A/B genetic fusion is a recently recognized entity that i …
Endometrial stromal sarcoma--the new genetic paradigm.
Lee CH, Nucci MR. Lee CH, et al. Histopathology. 2015 Jul;67(1):1-19. doi: 10.1111/his.12594. Epub 2015 Jan 22. Histopathology. 2015. PMID: 25355621 Review.
Low-grade ESSs frequently contain chromosomal rearrangements that result in JAZF1-SUZ12 fusion or equivalent genetic fusions. Although most low-grade ESSs show classic histological features that closely resemble those of proliferative-phase endometrial stroma, there …
Low-grade ESSs frequently contain chromosomal rearrangements that result in JAZF1-SUZ12 fusion or equivalent genetic fusions. …
Uterine sarcoma Part II-Uterine endometrial stromal sarcoma: The TAG systematic review.
Horng HC, Wen KC, Wang PH, Chen YJ, Yen MS, Ng HT; Taiwan Association of Gynecology Systematic Review Group. Horng HC, et al. Taiwan J Obstet Gynecol. 2016 Aug;55(4):472-9. doi: 10.1016/j.tjog.2016.04.034. Taiwan J Obstet Gynecol. 2016. PMID: 27590366 Free article. Review.
LG-ESS, a hormone-dependent tumor harboring chromosomal rearrangement, is an indolent tumor with a favorable prognosis, but characterized by late recurrences even in patients with Stage I disease, suggesting the requirement of a long-term follow-up. Patients with HG-ESS, based on …
LG-ESS, a hormone-dependent tumor harboring chromosomal rearrangement, is an indolent tumor with a favorable prognosis, but characterized by …
Clinical characteristics and prognostic factors of endometrial stromal sarcoma and undifferentiated uterine sarcoma confirmed by central pathologic review: A multi-institutional retrospective study from the Japanese Clinical Oncology Group.
Kikuchi A, Yoshida H, Tsuda H, Nishio S, Suzuki S, Takehara K, Kino N, Sumi T, Kato K, Yokoyama M, Nakamura K, Takano M, Sato S, Kato H, Tamate M, Horie K, Kato T, Sakamoto A, Fukunaga M, Kaku T, Yoshida M, Yaegashi N, Satoh T. Kikuchi A, et al. Gynecol Oncol. 2023 Sep;176:82-89. doi: 10.1016/j.ygyno.2023.07.002. Epub 2023 Jul 19. Gynecol Oncol. 2023. PMID: 37478616
Estrogen and progesterone receptors (PgRs) were examined by immunohistochemistry. JAZF1-SUZ12 and YWHAE-NUTM2A/B gene fusions were tested using real-time polymerase chain reaction. ...None of the 3 patients with YWHAE-NUTM2A/B fusion gene …
Estrogen and progesterone receptors (PgRs) were examined by immunohistochemistry. JAZF1-SUZ12 and YWHAE-NUTM2A/B gene fusio
Frequent expression of KIT in endometrial stromal sarcoma with YWHAE genetic rearrangement.
Lee CH, Hoang LN, Yip S, Reyes C, Marino-Enriquez A, Eilers G, Tao D, Chiang S, Fletcher JA, Soslow RA, Nucci MR, Oliva E. Lee CH, et al. Mod Pathol. 2014 May;27(5):751-7. doi: 10.1038/modpathol.2013.199. Epub 2013 Nov 1. Mod Pathol. 2014. PMID: 24186140 Free article.
Endometrial stromal sarcomas with the YWHAE-NUTM2A/B genetic fusion characteristically contain high-grade round to epithelioid cell component that is strongly and diffusely cyclin D1-positive and it may or may not show an associated low-grade fibroblastic/myx …
Endometrial stromal sarcomas with the YWHAE-NUTM2A/B genetic fusion characteristically contain high-grade round to epit …
YWHAE-rearranged high-grade endometrial stromal sarcoma: Two-center case series and response to chemotherapy.
Hemming ML, Wagner AJ, Nucci MR, Chiang S, Wang L, Hensley ML, George S. Hemming ML, et al. Gynecol Oncol. 2017 Jun;145(3):531-535. doi: 10.1016/j.ygyno.2017.03.021. Epub 2017 Apr 5. Gynecol Oncol. 2017. PMID: 28390819 Free PMC article.
OBJECTIVES: YWHAE-rearranged high-grade endometrial stromal sarcoma (HG-ESS) is a rare, recently defined uterine sarcoma harboring t(10;17)(q22;p13) resulting in YWHAE-NUTM2A/B fusion. Chemotherapy sensitivity of metastatic YWHAE-rearranged HG-E …
OBJECTIVES: YWHAE-rearranged high-grade endometrial stromal sarcoma (HG-ESS) is a rare, recently defined uterine sarcoma harboring t( …
Endometrial stromal sarcomas and related neoplasms: new developments and diagnostic considerations.
Hoang L, Chiang S, Lee CH. Hoang L, et al. Pathology. 2018 Feb;50(2):162-177. doi: 10.1016/j.pathol.2017.11.086. Epub 2017 Dec 22. Pathology. 2018. PMID: 29275929 Review.
Low-grade endometrial stromal sarcomas bear close histopathological resemblance to proliferative-type endometrial stroma, and approximately half harbour t(7;17)(p15;q21) resulting in JAZF1-SUZ12 gene fusion. Less common JAZF1-PHF1, EPC1-PHF1, MEAF6-PHF1, and MBTD1-CXorf67 …
Low-grade endometrial stromal sarcomas bear close histopathological resemblance to proliferative-type endometrial stroma, and approximately …
Targeted RNA expression profiling identifies high-grade endometrial stromal sarcoma as a clinically relevant molecular subtype of uterine sarcoma.
Momeni-Boroujeni A, Mohammad N, Wolber R, Yip S, Köbel M, Dickson BC, Hensley ML, Leitao MM Jr, Antonescu CR, Benayed R, Ladanyi M, Lee CH, Chiang S. Momeni-Boroujeni A, et al. Mod Pathol. 2021 May;34(5):1008-1016. doi: 10.1038/s41379-020-00705-6. Epub 2020 Oct 19. Mod Pathol. 2021. PMID: 33077922 Free article.
High-grade endometrial stromal sarcoma (HGESS) may harbor YWHAE-NUTM2A/B fusion, ZC3H7B-BCOR fusion, and BCOR internal tandem duplication (ITD). ...
High-grade endometrial stromal sarcoma (HGESS) may harbor YWHAE-NUTM2A/B fusion, ZC3H7B-BCOR fusion, and BCOR in …
Breast metastasis in high-grade endometrial stromal sarcoma (HG-ESS) with BCOR rearrangement: a case report of a novel metastatic site.
Fong A, Offman S. Fong A, et al. Diagn Pathol. 2023 Mar 2;18(1):34. doi: 10.1186/s13000-023-01313-z. Diagn Pathol. 2023. PMID: 36864468 Free PMC article.
This subset of tumour behaves similarly to YWHAE-NUTM2A/B HG-ESS, however, they are both morphologically and immunophenotypically distinct neoplasms. ...Preliminary investigations into BCOR HG-ESS have shown similar outcomes to YWHAE-NUTM2A/B HG-ESS, w …
This subset of tumour behaves similarly to YWHAE-NUTM2A/B HG-ESS, however, they are both morphologically and immunophenotypica …
12 results