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Structural and biochemical insights into purine-based drug molecules in hBRD2 delineate a unique binding mode opening new vistas in the design of inhibitors of the BET family.
Arole AH, Deshmukh P, Sridhar A, Mathur S, Mahalingaswamy M, Subramanya H, Dalavaikodihalli Nanjaiah N, Padmanabhan B. Arole AH, et al. Among authors: sridhar a. Acta Crystallogr D Struct Biol. 2023 Aug 1;79(Pt 8):758-774. doi: 10.1107/S2059798323005211. Epub 2023 Jul 11. Acta Crystallogr D Struct Biol. 2023. PMID: 37432115