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D-cycloserine or similar physiochemical compounds may be uniquely suited for use in Bacillus anthracis spore decontamination strategies.
J Appl Microbiol. 2013 Dec;115(6):1343-56. doi: 10.1111/jam.12322. Epub 2013 Aug 30.
J Appl Microbiol. 2013.
PMID: 23927578
Free article.
We investigated the efficacy of d-cycloserine (DCS), an antibiotic and inhibitor of the spore-associated enzyme (alanine racemase) responsible for converting l-alanine to d-alanine, as a spore germination enhancer and antimicrobial agent. ...CONCLUSIONS: These results furt …
We investigated the efficacy of d-cycloserine (DCS), an antibiotic and inhibitor of the spore-associated enzyme (alanine racemase) responsib …
A microtiter fluorometric assay to detect the germination of Bacillus anthracis spores and the germination inhibitory effects of antibodies.
Welkos SL, Cote CK, Rea KM, Gibbs PH.
Welkos SL, et al.
J Microbiol Methods. 2004 Feb;56(2):253-65. doi: 10.1016/j.mimet.2003.10.019.
J Microbiol Methods. 2004.
PMID: 14744454
Spore germination in the presence of several germinants was characterized. Although L-alanine and inosine alone stimulated rapid germination in this assay, a medium containing optimal concentrations of L-alanine, adenosine, and casamino acids gave low background flu …
Spore germination in the presence of several germinants was characterized. Although L-alanine and inosine alone stimulated rapid germ …
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