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Results: 1 to 20 of 262

1.

ATF4 licenses C/EBPβ activity in human mesenchymal stem cells primed for adipogenesis.

Cohen DM, Won KJ, Nguyen N, Lazar MA, Chen CS, Steger DJ.

Elife. 2015 Jun 25;4. doi: 10.7554/eLife.06821. [Epub ahead of print]

2.

GENE REGULATION. Discrete functions of nuclear receptor Rev-erbα couple metabolism to the clock.

Zhang Y, Fang B, Emmett MJ, Damle M, Sun Z, Feng D, Armour SM, Remsberg JR, Jager J, Soccio RE, Steger DJ, Lazar MA.

Science. 2015 Jun 26;348(6242):1488-92. doi: 10.1126/science.aab3021. Epub 2015 Jun 4.

PMID:
26044300
3.

Genomic redistribution of GR monomers and dimers mediates transcriptional response to exogenous glucocorticoid in vivo.

Lim HW, Uhlenhaut NH, Rauch A, Weiner J, Hübner S, Hübner N, Won KJ, Lazar MA, Tuckermann J, Steger DJ.

Genome Res. 2015 Jun;25(6):836-44. doi: 10.1101/gr.188581.114. Epub 2015 May 8.

PMID:
25957148
4.

Circadian metabolism in the light of evolution.

Gerhart-Hines Z, Lazar MA.

Endocr Rev. 2015 Jun;36(3):289-304. doi: 10.1210/er.2015-1007. Epub 2015 Apr 30.

PMID:
25927923
5.

PRDM16 binds MED1 and controls chromatin architecture to determine a brown fat transcriptional program.

Harms MJ, Lim HW, Ho Y, Shapira SN, Ishibashi J, Rajakumari S, Steger DJ, Lazar MA, Won KJ, Seale P.

Genes Dev. 2015 Feb 1;29(3):298-307. doi: 10.1101/gad.252734.114.

PMID:
25644604
6.

Macrophage-derived human resistin is induced in multiple helminth infections and promotes inflammatory monocytes and increased parasite burden.

Jang JC, Chen G, Wang SH, Barnes MA, Chung JI, Camberis M, Le Gros G, Cooper PJ, Steel C, Nutman TB, Lazar MA, Nair MG.

PLoS Pathog. 2015 Jan 8;11(1):e1004579. doi: 10.1371/journal.ppat.1004579. eCollection 2015 Jan.

7.

Circadian enhancers coordinate multiple phases of rhythmic gene transcription in vivo.

Fang B, Everett LJ, Jager J, Briggs E, Armour SM, Feng D, Roy A, Gerhart-Hines Z, Sun Z, Lazar MA.

Cell. 2014 Nov 20;159(5):1140-52. doi: 10.1016/j.cell.2014.10.022.

PMID:
25416951
8.

Nutrient-sensing nuclear receptors coordinate autophagy.

Lee JM, Wagner M, Xiao R, Kim KH, Feng D, Lazar MA, Moore DD.

Nature. 2014 Dec 4;516(7529):112-5. doi: 10.1038/nature13961. Epub 2014 Nov 12.

9.

Thiazolidinediones and the promise of insulin sensitization in type 2 diabetes.

Soccio RE, Chen ER, Lazar MA.

Cell Metab. 2014 Oct 7;20(4):573-91. doi: 10.1016/j.cmet.2014.08.005. Epub 2014 Sep 18.

PMID:
25242225
10.

Integrator regulates transcriptional initiation and pause release following activation.

Gardini A, Baillat D, Cesaroni M, Hu D, Marinis JM, Wagner EJ, Lazar MA, Shilatifard A, Shiekhattar R.

Mol Cell. 2014 Oct 2;56(1):128-39. doi: 10.1016/j.molcel.2014.08.004. Epub 2014 Sep 4.

PMID:
25201415
11.

Nuclear receptor Rev-erbα: up, down, and all around.

Everett LJ, Lazar MA.

Trends Endocrinol Metab. 2014 Nov;25(11):586-92. doi: 10.1016/j.tem.2014.06.011. Epub 2014 Jul 22.

PMID:
25066191
12.

Targeting macrophage Histone deacetylase 3 stabilizes atherosclerotic lesions.

Hoeksema MA, Gijbels MJ, Van den Bossche J, van der Velden S, Sijm A, Neele AE, Seijkens T, Stöger JL, Meiler S, Boshuizen MC, Dallinga-Thie GM, Levels JH, Boon L, Mullican SE, Spann NJ, Cleutjens JP, Glass CK, Lazar MA, de Vries CJ, Biessen EA, Daemen MJ, Lutgens E, de Winther MP.

EMBO Mol Med. 2014 Jul 9;6(9):1124-32. doi: 10.15252/emmm.201404170.

13.

PPARγ and the global map of adipogenesis and beyond.

Lefterova MI, Haakonsson AK, Lazar MA, Mandrup S.

Trends Endocrinol Metab. 2014 Jun;25(6):293-302. doi: 10.1016/j.tem.2014.04.001. Epub 2014 Apr 29. Review.

14.

Anti-diabetic rosiglitazone remodels the adipocyte transcriptome by redistributing transcription to PPARγ-driven enhancers.

Step SE, Lim HW, Marinis JM, Prokesch A, Steger DJ, You SH, Won KJ, Lazar MA.

Genes Dev. 2014 May 1;28(9):1018-28. doi: 10.1101/gad.237628.114.

15.

Adenylyl cyclase-associated protein 1 is a receptor for human resistin and mediates inflammatory actions of human monocytes.

Lee S, Lee HC, Kwon YW, Lee SE, Cho Y, Kim J, Lee S, Kim JY, Lee J, Yang HM, Mook-Jung I, Nam KY, Chung J, Lazar MA, Kim HS.

Cell Metab. 2014 Mar 4;19(3):484-97. doi: 10.1016/j.cmet.2014.01.013.

16.

Histone deacetylase 3 modulates Tbx5 activity to regulate early cardiogenesis.

Lewandowski SL, Janardhan HP, Smee KM, Bachman M, Sun Z, Lazar MA, Trivedi CM.

Hum Mol Genet. 2014 Jul 15;23(14):3801-9. doi: 10.1093/hmg/ddu093. Epub 2014 Feb 23.

PMID:
24565863
17.

Behavioral changes and dopaminergic dysregulation in mice lacking the nuclear receptor Rev-erbα.

Jager J, O'Brien WT, Manlove J, Krizman EN, Fang B, Gerhart-Hines Z, Robinson MB, Klein PS, Lazar MA.

Mol Endocrinol. 2014 Apr;28(4):490-8. doi: 10.1210/me.2013-1351. Epub 2014 Feb 19.

18.

Deacetylase-independent function of HDAC3 in transcription and metabolism requires nuclear receptor corepressor.

Sun Z, Feng D, Fang B, Mullican SE, You SH, Lim HW, Everett LJ, Nabel CS, Li Y, Selvakumaran V, Won KJ, Lazar MA.

Mol Cell. 2013 Dec 26;52(6):769-82. doi: 10.1016/j.molcel.2013.10.022. Epub 2013 Nov 21.

19.

Metabolite and transcriptome analysis during fasting suggest a role for the p53-Ddit4 axis in major metabolic tissues.

Schupp M, Chen F, Briggs ER, Rao S, Pelzmann HJ, Pessentheiner AR, Bogner-Strauss JG, Lazar MA, Baldwin D, Prokesch A.

BMC Genomics. 2013 Nov 5;14:758. doi: 10.1186/1471-2164-14-758.

20.

Histone deacetylase 3 coordinates commensal-bacteria-dependent intestinal homeostasis.

Alenghat T, Osborne LC, Saenz SA, Kobuley D, Ziegler CG, Mullican SE, Choi I, Grunberg S, Sinha R, Wynosky-Dolfi M, Snyder A, Giacomin PR, Joyce KL, Hoang TB, Bewtra M, Brodsky IE, Sonnenberg GF, Bushman FD, Won KJ, Lazar MA, Artis D.

Nature. 2013 Dec 5;504(7478):153-7. doi: 10.1038/nature12687. Epub 2013 Nov 3.

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