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Results: 1 to 20 of 95

1.

Aging of blood can be tracked by DNA methylation changes at just three CpG sites.

Weidner CI, Lin Q, Koch CM, Eisele L, Beier F, Ziegler P, Bauerschlag DO, Jöckel KH, Erbel R, Mühleisen TW, Zenke M, Brümmendorf TH, Wagner W.

Genome Biol. 2014 Feb 3;15(2):R24. doi: 10.1186/gb-2014-15-2-r24.

PMID:
24490752
[PubMed - in process]
Free PMC Article
2.

Epigenetic-aging-signature to determine age in different tissues.

Koch CM, Wagner W.

Aging (Albany NY). 2011 Oct;3(10):1018-27.

PMID:
22067257
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Specific age-associated DNA methylation changes in human dermal fibroblasts.

Koch CM, Suschek CV, Lin Q, Bork S, Goergens M, Joussen S, Pallua N, Ho AD, Zenke M, Wagner W.

PLoS One. 2011 Feb 8;6(2):e16679. doi: 10.1371/journal.pone.0016679.

PMID:
21347436
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Lack of increases in methylation at three CpG-rich genomic loci in non-mitotic adult tissues during aging.

Chu MW, Siegmund KD, Eckstam CL, Kim JY, Yang AS, Kanel GC, Tavaré S, Shibata D.

BMC Med Genet. 2007 Jul 31;8:50.

PMID:
17672908
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

The epigenetic tracks of aging.

Weidner CI, Wagner W.

Biol Chem. 2014 Sep 2. pii: /j/bchm.ahead-of-print/hsz-2014-0180/hsz-2014-0180.xml. doi: 10.1515/hsz-2014-0180. [Epub ahead of print]

PMID:
25205717
[PubMed - as supplied by publisher]
6.

Continuous Aging of the Human DNA Methylome Throughout the Human Lifespan.

Johansson A, Enroth S, Gyllensten U.

PLoS One. 2013 Jun 27;8(6):e67378. Print 2013.

PMID:
23826282
[PubMed - as supplied by publisher]
Free PMC Article
7.

Cross-sectional and longitudinal changes in DNA methylation with age: an epigenome-wide analysis revealing over 60 novel age-associated CpG sites.

Florath I, Butterbach K, Müller H, Bewerunge-Hudler M, Brenner H.

Hum Mol Genet. 2014 Mar 1;23(5):1186-201. doi: 10.1093/hmg/ddt531. Epub 2013 Oct 26.

PMID:
24163245
[PubMed - in process]
8.

Distinct DNA methylation changes highly correlated with chronological age in the human brain.

Hernandez DG, Nalls MA, Gibbs JR, Arepalli S, van der Brug M, Chong S, Moore M, Longo DL, Cookson MR, Traynor BJ, Singleton AB.

Hum Mol Genet. 2011 Mar 15;20(6):1164-72. doi: 10.1093/hmg/ddq561. Epub 2011 Jan 7.

PMID:
21216877
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Epigenome-wide scans identify differentially methylated regions for age and age-related phenotypes in a healthy ageing population.

Bell JT, Tsai PC, Yang TP, Pidsley R, Nisbet J, Glass D, Mangino M, Zhai G, Zhang F, Valdes A, Shin SY, Dempster EL, Murray RM, Grundberg E, Hedman AK, Nica A, Small KS; MuTHER Consortium, Dermitzakis ET, McCarthy MI, Mill J, Spector TD, Deloukas P.

PLoS Genet. 2012;8(4):e1002629. doi: 10.1371/journal.pgen.1002629. Epub 2012 Apr 19.

PMID:
22532803
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Telomere length is associated with disease severity and declines with age in dyskeratosis congenita.

Alter BP, Rosenberg PS, Giri N, Baerlocher GM, Lansdorp PM, Savage SA.

Haematologica. 2012 Mar;97(3):353-9. doi: 10.3324/haematol.2011.055269. Epub 2011 Nov 4.

PMID:
22058220
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Proof of principle: quality control of therapeutic cell preparations using senescence-associated DNA-methylation changes.

Schellenberg A, Mauen S, Koch CM, Jans R, de Waele P, Wagner W.

BMC Res Notes. 2014 Apr 23;7:254. doi: 10.1186/1756-0500-7-254.

PMID:
24755407
[PubMed - in process]
Free PMC Article
12.

Induced pluripotent mesenchymal stromal cell clones retain donor-derived differences in DNA methylation profiles.

Shao K, Koch C, Gupta MK, Lin Q, Lenz M, Laufs S, Denecke B, Schmidt M, Linke M, Hennies HC, Hescheler J, Zenke M, Zechner U, Šarić T, Wagner W.

Mol Ther. 2013 Jan;21(1):240-50. doi: 10.1038/mt.2012.207. Epub 2012 Oct 2.

PMID:
23032973
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Age-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer.

Teschendorff AE, Menon U, Gentry-Maharaj A, Ramus SJ, Weisenberger DJ, Shen H, Campan M, Noushmehr H, Bell CG, Maxwell AP, Savage DA, Mueller-Holzner E, Marth C, Kocjan G, Gayther SA, Jones A, Beck S, Wagner W, Laird PW, Jacobs IJ, Widschwendter M.

Genome Res. 2010 Apr;20(4):440-6. doi: 10.1101/gr.103606.109. Epub 2010 Mar 10.

PMID:
20219944
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Detection of differential mitotic cell age in bone marrow CD34(+) cells from patients with myelodysplastic syndrome and acute leukemia by analysis of an epigenetic molecular clock DNA signature.

Mossner M, Hopfer O, Nowak D, Baldus CD, Neumann U, Kmetsch A, Benlasfer O, John T, Perka C, Thiel E, Hofmann WK.

Exp Hematol. 2010 Aug;38(8):661-5. doi: 10.1016/j.exphem.2010.03.022. Epub 2010 Jun 16.

PMID:
20399247
[PubMed - indexed for MEDLINE]
15.

DNA methylation pattern changes upon long-term culture and aging of human mesenchymal stromal cells.

Bork S, Pfister S, Witt H, Horn P, Korn B, Ho AD, Wagner W.

Aging Cell. 2010 Feb;9(1):54-63. doi: 10.1111/j.1474-9726.2009.00535.x. Epub 2009 Nov 6.

PMID:
19895632
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

The relationship between DNA methylation and telomere length in dyskeratosis congenita.

Gadalla SM, Katki HA, Shebl FM, Giri N, Alter BP, Savage SA.

Aging Cell. 2012 Feb;11(1):24-8. doi: 10.1111/j.1474-9726.2011.00755.x. Epub 2011 Nov 15.

PMID:
21981348
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

The determination of tissue-specific DNA methylation patterns in forensic biofluids using bisulfite modification and pyrosequencing.

Madi T, Balamurugan K, Bombardi R, Duncan G, McCord B.

Electrophoresis. 2012 Jul;33(12):1736-45. doi: 10.1002/elps.201100711.

PMID:
22740462
[PubMed - indexed for MEDLINE]
18.

Epigenetic biomarker to determine replicative senescence of cultured cells.

Koch CM, Wagner W.

Methods Mol Biol. 2013;1048:309-21. doi: 10.1007/978-1-62703-556-9_20.

PMID:
23929112
[PubMed - indexed for MEDLINE]
19.

Heterogeneity in white blood cells has potential to confound DNA methylation measurements.

Adalsteinsson BT, Gudnason H, Aspelund T, Harris TB, Launer LJ, Eiriksdottir G, Smith AV, Gudnason V.

PLoS One. 2012;7(10):e46705. doi: 10.1371/journal.pone.0046705. Epub 2012 Oct 5.

PMID:
23071618
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Telomere shortening and loss of self-renewal in dyskeratosis congenita induced pluripotent stem cells.

Batista LF, Pech MF, Zhong FL, Nguyen HN, Xie KT, Zaug AJ, Crary SM, Choi J, Sebastiano V, Cherry A, Giri N, Wernig M, Alter BP, Cech TR, Savage SA, Reijo Pera RA, Artandi SE.

Nature. 2011 May 22;474(7351):399-402. doi: 10.1038/nature10084.

PMID:
21602826
[PubMed - indexed for MEDLINE]
Free PMC Article

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