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Results: 1 to 20 of 92

1.

The genetic heterogeneity and mutational burden of engineered melanomas in zebrafish models.

Yen J, White RM, Wedge DC, Van Loo P, de Ridder J, Capper A, Richardson J, Jones D, Raine K, Watson IR, Wu CJ, Cheng J, Martincorena I, Nik-Zainal S, Mudie L, Moreau Y, Marshall J, Ramakrishna M, Tarpey P, Shlien A, Whitmore I, Gamble S, Latimer C, Langdon E, Kaufman C, Dovey M, Taylor A, Menzies A, McLaren S, O'Meara S, Butler A, Teague J, Lister J, Chin L, Campbell P, Adams DJ, Zon LI, Patton EE, Stemple DL, Futreal PA.

Genome Biol. 2013;14(10):R113.

PMID:
24148783
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

[Characterization of genetic alterations in primary human melanomas carrying BRAF or NRAS mutation].

Lázár V.

Magy Onkol. 2013 Jun;57(2):96-9. doi: MagyOnkol.2013.57.2.96. Epub 2013 May 20. Hungarian.

PMID:
23795354
[PubMed - indexed for MEDLINE]
Free Article
3.

Marked genetic differences between BRAF and NRAS mutated primary melanomas as revealed by array comparative genomic hybridization.

Lázár V, Ecsedi S, Vízkeleti L, Rákosy Z, Boross G, Szappanos B, Bégány A, Emri G, Adány R, Balázs M.

Melanoma Res. 2012 Jun;22(3):202-14. doi: 10.1097/CMR.0b013e328352dbc8.

PMID:
22456166
[PubMed - indexed for MEDLINE]
4.

Oncogenic NRAS cooperates with p53 loss to generate melanoma in zebrafish.

Dovey M, White RM, Zon LI.

Zebrafish. 2009 Dec;6(4):397-404. doi: 10.1089/zeb.2009.0606.

PMID:
19954345
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

BRAF mutations are sufficient to promote nevi formation and cooperate with p53 in the genesis of melanoma.

Patton EE, Widlund HR, Kutok JL, Kopani KR, Amatruda JF, Murphey RD, Berghmans S, Mayhall EA, Traver D, Fletcher CD, Aster JC, Granter SR, Look AT, Lee C, Fisher DE, Zon LI.

Curr Biol. 2005 Feb 8;15(3):249-54.

PMID:
15694309
[PubMed - indexed for MEDLINE]
Free Article
6.

The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset.

Ceol CJ, Houvras Y, Jane-Valbuena J, Bilodeau S, Orlando DA, Battisti V, Fritsch L, Lin WM, Hollmann TJ, Ferré F, Bourque C, Burke CJ, Turner L, Uong A, Johnson LA, Beroukhim R, Mermel CH, Loda M, Ait-Si-Ali S, Garraway LA, Young RA, Zon LI.

Nature. 2011 Mar 24;471(7339):513-7. doi: 10.1038/nature09806.

PMID:
21430779
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Frequency of UV-inducible NRAS mutations in melanomas of patients with germline CDKN2A mutations.

Eskandarpour M, Hashemi J, Kanter L, Ringborg U, Platz A, Hansson J.

J Natl Cancer Inst. 2003 Jun 4;95(11):790-8.

PMID:
12783933
[PubMed - indexed for MEDLINE]
Free Article
8.

Frequent alterations of Ras signaling pathway genes in sporadic malignant melanomas.

Reifenberger J, Knobbe CB, Sterzinger AA, Blaschke B, Schulte KW, Ruzicka T, Reifenberger G.

Int J Cancer. 2004 Apr 10;109(3):377-84.

PMID:
14961576
[PubMed - indexed for MEDLINE]
9.

NRAS and BRAF mutations in melanoma-associated nevi and uninvolved nevi.

Tschandl P, Berghoff AS, Preusser M, Burgstaller-Muehlbacher S, Pehamberger H, Okamoto I, Kittler H.

PLoS One. 2013 Jul 8;8(7):e69639. doi: 10.1371/journal.pone.0069639. Print 2013.

PMID:
23861977
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

BRAF/NRAS wild-type melanomas have a high mutation load correlating with histologic and molecular signatures of UV damage.

Mar VJ, Wong SQ, Li J, Scolyer RA, McLean C, Papenfuss AT, Tothill RW, Kakavand H, Mann GJ, Thompson JF, Behren A, Cebon JS, Wolfe R, Kelly JW, Dobrovic A, McArthur GA.

Clin Cancer Res. 2013 Sep 1;19(17):4589-98. doi: 10.1158/1078-0432.CCR-13-0398. Epub 2013 Jul 5.

PMID:
23833303
[PubMed - indexed for MEDLINE]
Free Article
11.

Distinct sets of genetic alterations in melanoma.

Curtin JA, Fridlyand J, Kageshita T, Patel HN, Busam KJ, Kutzner H, Cho KH, Aiba S, Bröcker EB, LeBoit PE, Pinkel D, Bastian BC.

N Engl J Med. 2005 Nov 17;353(20):2135-47.

PMID:
16291983
[PubMed - indexed for MEDLINE]
Free Article
12.

Characterization of candidate gene copy number alterations in the 11q13 region along with BRAF and NRAS mutations in human melanoma.

Lázár V, Ecsedi S, Szöllosi AG, Tóth R, Vízkeleti L, Rákosy Z, Bégány A, Adány R, Balázs M.

Mod Pathol. 2009 Oct;22(10):1367-78. doi: 10.1038/modpathol.2009.109. Epub 2009 Jul 24.

PMID:
19633643
[PubMed - indexed for MEDLINE]
Free Article
13.

Distinct patterns of DNA copy number alterations associate with BRAF mutations in melanomas and melanoma-derived cell lines.

Greshock J, Nathanson K, Medina A, Ward MR, Herlyn M, Weber BL, Zaks TZ.

Genes Chromosomes Cancer. 2009 May;48(5):419-28. doi: 10.1002/gcc.20651.

PMID:
19226609
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Prevalence of BRAF V600E mutation in Chinese melanoma patients: large scale analysis of BRAF and NRAS mutations in a 432-case cohort.

Si L, Kong Y, Xu X, Flaherty KT, Sheng X, Cui C, Chi Z, Li S, Mao L, Guo J.

Eur J Cancer. 2012 Jan;48(1):94-100. doi: 10.1016/j.ejca.2011.06.056. Epub 2011 Jul 23.

PMID:
21788131
[PubMed - indexed for MEDLINE]
15.

Mutation analysis of the EGFR-NRAS-BRAF pathway in melanomas from black Africans and other subgroups of cutaneous melanoma.

Akslen LA, Puntervoll H, Bachmann IM, Straume O, Vuhahula E, Kumar R, Molven A.

Melanoma Res. 2008 Feb;18(1):29-35. doi: 10.1097/CMR.0b013e3282f32517.

PMID:
18227705
[PubMed - indexed for MEDLINE]
16.

Human malignant melanoma: detection of BRAF- and c-kit-activating mutations by high-resolution amplicon melting analysis.

Willmore-Payne C, Holden JA, Tripp S, Layfield LJ.

Hum Pathol. 2005 May;36(5):486-93.

PMID:
15948115
[PubMed - indexed for MEDLINE]
17.

Gene expression signature associated with BRAF mutations in human primary cutaneous melanomas.

Kannengiesser C, Spatz A, Michiels S, Eychène A, Dessen P, Lazar V, Winnepenninckx V, Lesueur F, Druillennec S, Robert C, van den Oord JJ, Sarasin A, Bressac-de Paillerets B; EORTC Melanoma group.

Mol Oncol. 2008 Apr;1(4):425-30. doi: 10.1016/j.molonc.2008.01.002. Epub 2008 Jan 12.

PMID:
19383316
[PubMed - indexed for MEDLINE]
Free Article
18.

Absence of BRAF mutations in UV-protected mucosal melanomas.

Edwards RH, Ward MR, Wu H, Medina CA, Brose MS, Volpe P, Nussen-Lee S, Haupt HM, Martin AM, Herlyn M, Lessin SR, Weber BL.

J Med Genet. 2004 Apr;41(4):270-2.

PMID:
15060100
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Novel somatic mutations to PI3K pathway genes in metastatic melanoma.

Shull AY, Latham-Schwark A, Ramasamy P, Leskoske K, Oroian D, Birtwistle MR, Buckhaults PJ.

PLoS One. 2012;7(8):e43369. doi: 10.1371/journal.pone.0043369. Epub 2012 Aug 17.

PMID:
22912864
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Oncogene abnormalities in a series of primary melanomas of the sinonasal tract: NRAS mutations and cyclin D1 amplification are more frequent than KIT or BRAF mutations.

Chraybi M, Abd Alsamad I, Copie-Bergman C, Baia M, André J, Dumaz N, Ortonne N.

Hum Pathol. 2013 Sep;44(9):1902-11. doi: 10.1016/j.humpath.2013.01.025. Epub 2013 May 9.

PMID:
23664541
[PubMed - indexed for MEDLINE]
Free PMC Article

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