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Results: 1 to 20 of 87

1.

Pint lincRNA connects the p53 pathway with epigenetic silencing by the Polycomb repressive complex 2.

Marín-Béjar O, Marchese FP, Athie A, Sánchez Y, González J, Segura V, Huang L, Moreno I, Navarro A, Monzó M, García-Foncillas J, Rinn JL, Guo S, Huarte M.

Genome Biol. 2013;14(9):R104.

PMID:
24070194
[PubMed - in process]
Free PMC Article
2.

linc-UBC1 physically associates with polycomb repressive complex 2 (PRC2) and acts as a negative prognostic factor for lymph node metastasis and survival in bladder cancer.

He W, Cai Q, Sun F, Zhong G, Wang P, Liu H, Luo J, Yu H, Huang J, Lin T.

Biochim Biophys Acta. 2013 Oct;1832(10):1528-37. doi: 10.1016/j.bbadis.2013.05.010. Epub 2013 May 18.

PMID:
23688781
[PubMed - indexed for MEDLINE]
3.

The intronic long noncoding RNA ANRASSF1 recruits PRC2 to the RASSF1A promoter, reducing the expression of RASSF1A and increasing cell proliferation.

Beckedorff FC, Ayupe AC, Crocci-Souza R, Amaral MS, Nakaya HI, Soltys DT, Menck CF, Reis EM, Verjovski-Almeida S.

PLoS Genet. 2013;9(8):e1003705. doi: 10.1371/journal.pgen.1003705. Epub 2013 Aug 22.

PMID:
23990798
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Genetic and epigenetic regulation of human lincRNA gene expression.

Popadin K, Gutierrez-Arcelus M, Dermitzakis ET, Antonarakis SE.

Am J Hum Genet. 2013 Dec 5;93(6):1015-26. doi: 10.1016/j.ajhg.2013.10.022. Epub 2013 Nov 21.

PMID:
24268656
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response.

Huarte M, Guttman M, Feldser D, Garber M, Koziol MJ, Kenzelmann-Broz D, Khalil AM, Zuk O, Amit I, Rabani M, Attardi LD, Regev A, Lander ES, Jacks T, Rinn JL.

Cell. 2010 Aug 6;142(3):409-19. doi: 10.1016/j.cell.2010.06.040.

PMID:
20673990
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

LincRNA-p21 activates p21 in cis to promote Polycomb target gene expression and to enforce the G1/S checkpoint.

Dimitrova N, Zamudio JR, Jong RM, Soukup D, Resnick R, Sarma K, Ward AJ, Raj A, Lee JT, Sharp PA, Jacks T.

Mol Cell. 2014 Jun 5;54(5):777-90. doi: 10.1016/j.molcel.2014.04.025. Epub 2014 May 22.

PMID:
24857549
[PubMed - indexed for MEDLINE]
7.

Clinical significance of long intergenic noncoding RNA-p21 in colorectal cancer.

Zhai H, Fesler A, Schee K, Fodstad O, Flatmark K, Ju J.

Clin Colorectal Cancer. 2013 Dec;12(4):261-6. doi: 10.1016/j.clcc.2013.06.003. Epub 2013 Sep 5.

PMID:
24012455
[PubMed - indexed for MEDLINE]
8.

Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression.

Khalil AM, Guttman M, Huarte M, Garber M, Raj A, Rivea Morales D, Thomas K, Presser A, Bernstein BE, van Oudenaarden A, Regev A, Lander ES, Rinn JL.

Proc Natl Acad Sci U S A. 2009 Jul 14;106(28):11667-72. doi: 10.1073/pnas.0904715106. Epub 2009 Jul 1.

PMID:
19571010
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

LincRNA-p21 Regulates Neointima Formation, Vascular Smooth Muscle Cell Proliferation, Apoptosis and Atherosclerosis by Enhancing p53 Activity.

Wu G, Cai J, Han Y, Chen J, Huang ZP, Chen C, Cai Y, Huang H, Yang Y, Liu Y, Xu Z, He D, Zhang X, Hu X, Pinello L, Zhong D, He F, Yuan GC, Wang DZ, Zeng C.

Circulation. 2014 Aug 25. pii: CIRCULATIONAHA.114.011675. [Epub ahead of print]

PMID:
25156994
[PubMed - as supplied by publisher]
10.

PRC2/EED-EZH2 complex is up-regulated in breast cancer lymph node metastasis compared to primary tumor and correlates with tumor proliferation in situ.

Yu H, Simons DL, Segall I, Carcamo-Cavazos V, Schwartz EJ, Yan N, Zuckerman NS, Dirbas FM, Johnson DL, Holmes SP, Lee PP.

PLoS One. 2012;7(12):e51239. doi: 10.1371/journal.pone.0051239. Epub 2012 Dec 10.

PMID:
23251464
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

The histone H3K27 methylation mark regulates intestinal epithelial cell density-dependent proliferation and the inflammatory response.

Turgeon N, Blais M, Delabre JF, Asselin C.

J Cell Biochem. 2013 May;114(5):1203-15. doi: 10.1002/jcb.24463.

PMID:
23192652
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Protein arginine methyltransferase 5 (PRMT5) inhibition induces lymphoma cell death through reactivation of the retinoblastoma tumor suppressor pathway and polycomb repressor complex 2 (PRC2) silencing.

Chung J, Karkhanis V, Tae S, Yan F, Smith P, Ayers LW, Agostinelli C, Pileri S, Denis GV, Baiocchi RA, Sif S.

J Biol Chem. 2013 Dec 6;288(49):35534-47. doi: 10.1074/jbc.M113.510669. Epub 2013 Nov 4.

PMID:
24189068
[PubMed - indexed for MEDLINE]
13.

Polycomb group protein PHF1 regulates p53-dependent cell growth arrest and apoptosis.

Yang Y, Wang C, Zhang P, Gao K, Wang D, Yu H, Zhang T, Jiang S, Hexige S, Hong Z, Yasui A, Liu JO, Huang H, Yu L.

J Biol Chem. 2013 Jan 4;288(1):529-39. doi: 10.1074/jbc.M111.338996. Epub 2012 Nov 13.

PMID:
23150668
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Transposable elements reveal a stem cell-specific class of long noncoding RNAs.

Kelley D, Rinn J.

Genome Biol. 2012 Nov 26;13(11):R107. doi: 10.1186/gb-2012-13-11-r107.

PMID:
23181609
[PubMed - in process]
Free PMC Article
15.

TP53 genomic status regulates sensitivity of gastric cancer cells to the histone methylation inhibitor 3-deazaneplanocin A (DZNep).

Cheng LL, Itahana Y, Lei ZD, Chia NY, Wu Y, Yu Y, Zhang SL, Thike AA, Pandey A, Rozen S, Voorhoeve PM, Yu Q, Tan PH, Bay BH, Itahana K, Tan P.

Clin Cancer Res. 2012 Aug 1;18(15):4201-12. doi: 10.1158/1078-0432.CCR-12-0036. Epub 2012 Jun 6.

PMID:
22675170
[PubMed - indexed for MEDLINE]
Free Article
16.

The polycomb repressive complex 2 is a potential target of SUMO modifications.

Riising EM, Boggio R, Chiocca S, Helin K, Pasini D.

PLoS One. 2008 Jul 16;3(7):e2704. doi: 10.1371/journal.pone.0002704.

PMID:
18628979
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

P53-regulated long non-coding RNA TUG1 affects cell proliferation in human non-small cell lung cancer, partly through epigenetically regulating HOXB7 expression.

Zhang EB, Yin DD, Sun M, Kong R, Liu XH, You LH, Han L, Xia R, Wang KM, Yang JS, De W, Shu YQ, Wang ZX.

Cell Death Dis. 2014 May 22;5:e1243. doi: 10.1038/cddis.2014.201.

PMID:
24853421
[PubMed - in process]
Free PMC Article
18.

Polycomb mediated epigenetic silencing and replication timing at the INK4a/ARF locus during senescence.

Agherbi H, Gaussmann-Wenger A, Verthuy C, Chasson L, Serrano M, Djabali M.

PLoS One. 2009 May 20;4(5):e5622. doi: 10.1371/journal.pone.0005622.

PMID:
19462008
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Bromodomain protein 7 interacts with PRMT5 and PRC2, and is involved in transcriptional repression of their target genes.

Tae S, Karkhanis V, Velasco K, Yaneva M, Erdjument-Bromage H, Tempst P, Sif S.

Nucleic Acids Res. 2011 Jul;39(13):5424-38. doi: 10.1093/nar/gkr170. Epub 2011 Mar 29.

PMID:
21447565
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Roles of long noncoding RNAs in brain development, functional diversification and neurodegenerative diseases.

Wu P, Zuo X, Deng H, Liu X, Liu L, Ji A.

Brain Res Bull. 2013 Aug;97:69-80. doi: 10.1016/j.brainresbull.2013.06.001. Epub 2013 Jun 10. Review.

PMID:
23756188
[PubMed - indexed for MEDLINE]

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