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Results: 1 to 20 of 94

1.

Deep C diving: mapping the low-abundance modifications of the DNA demethylation pathway.

Thomson JP, Hunter JM, Meehan RR.

Genome Biol. 2013 May 29;14(5):118. doi: 10.1186/gb-2013-14-5-118.

PMID:
23732041
[PubMed - in process]
Free PMC Article
2.

TET enzymes, TDG and the dynamics of DNA demethylation.

Kohli RM, Zhang Y.

Nature. 2013 Oct 24;502(7472):472-9. doi: 10.1038/nature12750. Review.

PMID:
24153300
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Tet and TDG mediate DNA demethylation essential for mesenchymal-to-epithelial transition in somatic cell reprogramming.

Hu X, Zhang L, Mao SQ, Li Z, Chen J, Zhang RR, Wu HP, Gao J, Guo F, Liu W, Xu GF, Dai HQ, Shi YG, Li X, Hu B, Tang F, Pei D, Xu GL.

Cell Stem Cell. 2014 Apr 3;14(4):512-22. doi: 10.1016/j.stem.2014.01.001. Epub 2014 Feb 13.

PMID:
24529596
[PubMed - in process]
4.

Thymine DNA glycosylase can rapidly excise 5-formylcytosine and 5-carboxylcytosine: potential implications for active demethylation of CpG sites.

Maiti A, Drohat AC.

J Biol Chem. 2011 Oct 14;286(41):35334-8. doi: 10.1074/jbc.C111.284620. Epub 2011 Aug 23.

PMID:
21862836
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Genome-wide analysis reveals TET- and TDG-dependent 5-methylcytosine oxidation dynamics.

Shen L, Wu H, Diep D, Yamaguchi S, D'Alessio AC, Fung HL, Zhang K, Zhang Y.

Cell. 2013 Apr 25;153(3):692-706. doi: 10.1016/j.cell.2013.04.002. Epub 2013 Apr 18.

PMID:
23602152
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA.

He YF, Li BZ, Li Z, Liu P, Wang Y, Tang Q, Ding J, Jia Y, Chen Z, Li L, Sun Y, Li X, Dai Q, Song CX, Zhang K, He C, Xu GL.

Science. 2011 Sep 2;333(6047):1303-7. doi: 10.1126/science.1210944. Epub 2011 Aug 4.

PMID:
21817016
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Transient accumulation of 5-carboxylcytosine indicates involvement of active demethylation in lineage specification of neural stem cells.

Wheldon LM, Abakir A, Ferjentsik Z, Dudnakova T, Strohbuecker S, Christie D, Dai N, Guan S, Foster JM, Corrêa IR Jr, Loose M, Dixon JE, Sottile V, Johnson AD, Ruzov A.

Cell Rep. 2014 Jun 12;7(5):1353-61. doi: 10.1016/j.celrep.2014.05.003. Epub 2014 May 29.

PMID:
24882006
[PubMed - in process]
Free Article
8.

Ten-eleven translocation (Tet) and thymine DNA glycosylase (TDG), components of the demethylation pathway, are direct targets of miRNA-29a.

Zhang P, Huang B, Xu X, Sessa WC.

Biochem Biophys Res Commun. 2013 Aug 2;437(3):368-73. doi: 10.1016/j.bbrc.2013.06.082. Epub 2013 Jun 29.

PMID:
23820384
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Excision of 5-hydroxymethyluracil and 5-carboxylcytosine by the thymine DNA glycosylase domain: its structural basis and implications for active DNA demethylation.

Hashimoto H, Hong S, Bhagwat AS, Zhang X, Cheng X.

Nucleic Acids Res. 2012 Nov 1;40(20):10203-14. doi: 10.1093/nar/gks845. Epub 2012 Sep 8.

PMID:
22962365
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

DNA demethylation, Tet proteins and 5-hydroxymethylcytosine in epigenetic reprogramming: An emerging complex story.

Hill PW, Amouroux R, Hajkova P.

Genomics. 2014 Aug 27. pii: S0888-7543(14)00154-2. doi: 10.1016/j.ygeno.2014.08.012. [Epub ahead of print] Review.

PMID:
25173569
[PubMed - as supplied by publisher]
11.

PRDM14 promotes active DNA demethylation through the ten-eleven translocation (TET)-mediated base excision repair pathway in embryonic stem cells.

Okashita N, Kumaki Y, Ebi K, Nishi M, Okamoto Y, Nakayama M, Hashimoto S, Nakamura T, Sugasawa K, Kojima N, Takada T, Okano M, Seki Y.

Development. 2014 Jan;141(2):269-80. doi: 10.1242/dev.099622. Epub 2013 Dec 11.

PMID:
24335252
[PubMed - indexed for MEDLINE]
Free Article
12.

Ascorbic acid enhances Tet-mediated 5-methylcytosine oxidation and promotes DNA demethylation in mammals.

Yin R, Mao SQ, Zhao B, Chong Z, Yang Y, Zhao C, Zhang D, Huang H, Gao J, Li Z, Jiao Y, Li C, Liu S, Wu D, Gu W, Yang YG, Xu GL, Wang H.

J Am Chem Soc. 2013 Jul 17;135(28):10396-403. doi: 10.1021/ja4028346. Epub 2013 Jul 1.

PMID:
23768208
[PubMed - indexed for MEDLINE]
13.

Base excision repair of tandem modifications in a methylated CpG dinucleotide.

Sassa A, Cağlayan M, Dyrkheeva NS, Beard WA, Wilson SH.

J Biol Chem. 2014 May 16;289(20):13996-4008. doi: 10.1074/jbc.M114.557769. Epub 2014 Apr 2.

PMID:
24695738
[PubMed - in process]
14.

TET-mediated oxidation of methylcytosine causes TDG or NEIL glycosylase dependent gene reactivation.

Müller U, Bauer C, Siegl M, Rottach A, Leonhardt H.

Nucleic Acids Res. 2014 Sep 1;42(13):8592-604. doi: 10.1093/nar/gku552. Epub 2014 Jun 19.

PMID:
24948610
[PubMed - in process]
Free PMC Article
15.

Tet family of 5-methylcytosine dioxygenases in mammalian development.

Zhao H, Chen T.

J Hum Genet. 2013 Jul;58(7):421-7. doi: 10.1038/jhg.2013.63. Epub 2013 May 30. Review.

PMID:
23719188
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Analysis of TET expression/activity and 5mC oxidation during normal and malignant germ cell development.

Nettersheim D, Heukamp LC, Fronhoffs F, Grewe MJ, Haas N, Waha A, Honecker F, Waha A, Kristiansen G, Schorle H.

PLoS One. 2013 Dec 26;8(12):e82881. doi: 10.1371/journal.pone.0082881. eCollection 2013.

PMID:
24386123
[PubMed - in process]
Free PMC Article
17.

Specific transcriptional enhancement of inducible nitric oxide synthase by targeted promoter demethylation.

Gregory DJ, Zhang Y, Kobzik L, Fedulov AV.

Epigenetics. 2013 Nov;8(11):1205-12. doi: 10.4161/epi.26267. Epub 2013 Sep 5.

PMID:
24008769
[PubMed - in process]
18.

TET proteins: on the frenetic hunt for new cytosine modifications.

Delatte B, Fuks F.

Brief Funct Genomics. 2013 May;12(3):191-204. doi: 10.1093/bfgp/elt010. Epub 2013 Apr 26. Review.

PMID:
23625996
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Lesion processing by a repair enzyme is severely curtailed by residues needed to prevent aberrant activity on undamaged DNA.

Maiti A, Noon MS, MacKerell AD Jr, Pozharski E, Drohat AC.

Proc Natl Acad Sci U S A. 2012 May 22;109(21):8091-6. doi: 10.1073/pnas.1201010109. Epub 2012 May 9.

PMID:
22573813
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Vitamin C induces Tet-dependent DNA demethylation and a blastocyst-like state in ES cells.

Blaschke K, Ebata KT, Karimi MM, Zepeda-Martínez JA, Goyal P, Mahapatra S, Tam A, Laird DJ, Hirst M, Rao A, Lorincz MC, Ramalho-Santos M.

Nature. 2013 Aug 8;500(7461):222-6. doi: 10.1038/nature12362. Epub 2013 Jun 30.

PMID:
23812591
[PubMed - indexed for MEDLINE]
Free PMC Article

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