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Results: 1 to 20 of 97

1.

5-Hydroxymethylcytosine is an essential intermediate of active DNA demethylation processes in primary human monocytes.

Klug M, Schmidhofer S, Gebhard C, Andreesen R, Rehli M.

Genome Biol. 2013 May 26;14(5):R46. doi: 10.1186/gb-2013-14-5-r46.

PMID:
23705593
[PubMed - in process]
Free PMC Article
2.

Hydroquinone increases 5-hydroxymethylcytosine formation through ten eleven translocation 1 (TET1) 5-methylcytosine dioxygenase.

Coulter JB, O'Driscoll CM, Bressler JP.

J Biol Chem. 2013 Oct 4;288(40):28792-800. doi: 10.1074/jbc.M113.491365. Epub 2013 Aug 12.

PMID:
23940045
[PubMed - indexed for MEDLINE]
3.

TET2 as an epigenetic master regulator for normal and malignant hematopoiesis.

Nakajima H, Kunimoto H.

Cancer Sci. 2014 Jul 9. doi: 10.1111/cas.12484. [Epub ahead of print]

PMID:
25040794
[PubMed - as supplied by publisher]
4.

Loss of 5-hydroxymethylcytosine is accompanied with malignant cellular transformation.

Kudo Y, Tateishi K, Yamamoto K, Yamamoto S, Asaoka Y, Ijichi H, Nagae G, Yoshida H, Aburatani H, Koike K.

Cancer Sci. 2012 Apr;103(4):670-6. doi: 10.1111/j.1349-7006.2012.02213.x. Epub 2012 Feb 27.

PMID:
22320381
[PubMed - indexed for MEDLINE]
5.

PRDM14 promotes active DNA demethylation through the ten-eleven translocation (TET)-mediated base excision repair pathway in embryonic stem cells.

Okashita N, Kumaki Y, Ebi K, Nishi M, Okamoto Y, Nakayama M, Hashimoto S, Nakamura T, Sugasawa K, Kojima N, Takada T, Okano M, Seki Y.

Development. 2014 Jan;141(2):269-80. doi: 10.1242/dev.099622. Epub 2013 Dec 11.

PMID:
24335252
[PubMed - indexed for MEDLINE]
Free Article
6.

Active DNA demethylation in human postmitotic cells correlates with activating histone modifications, but not transcription levels.

Klug M, Heinz S, Gebhard C, Schwarzfischer L, Krause SW, Andreesen R, Rehli M.

Genome Biol. 2010;11(6):R63. doi: 10.1186/gb-2010-11-6-r63. Epub 2010 Jun 18.

PMID:
20565882
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Ascorbate induces ten-eleven translocation (Tet) methylcytosine dioxygenase-mediated generation of 5-hydroxymethylcytosine.

Minor EA, Court BL, Young JI, Wang G.

J Biol Chem. 2013 May 10;288(19):13669-74. doi: 10.1074/jbc.C113.464800. Epub 2013 Apr 2.

PMID:
23548903
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Advances in DNA methylation: 5-hydroxymethylcytosine revisited.

Dahl C, Grønbæk K, Guldberg P.

Clin Chim Acta. 2011 May 12;412(11-12):831-6. doi: 10.1016/j.cca.2011.02.013. Epub 2011 Feb 12. Review.

PMID:
21324307
[PubMed - indexed for MEDLINE]
9.

PU.1 target genes undergo Tet2-coupled demethylation and DNMT3b-mediated methylation in monocyte-to-osteoclast differentiation.

de la Rica L, Rodríguez-Ubreva J, García M, Islam AB, Urquiza JM, Hernando H, Christensen J, Helin K, Gómez-Vaquero C, Ballestar E.

Genome Biol. 2013;14(9):R99.

PMID:
24028770
[PubMed - in process]
Free PMC Article
10.

TET2 plays an essential role in erythropoiesis by regulating lineage-specific genes via DNA oxidative demethylation in a zebrafish model.

Ge L, Zhang RP, Wan F, Guo DY, Wang P, Xiang LX, Shao JZ.

Mol Cell Biol. 2014 Mar;34(6):989-1002. doi: 10.1128/MCB.01061-13. Epub 2014 Jan 6.

PMID:
24396069
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

The Ten-Eleven Translocation-2 (TET2) gene in hematopoiesis and hematopoietic diseases.

Solary E, Bernard OA, Tefferi A, Fuks F, Vainchenker W.

Leukemia. 2014 Mar;28(3):485-96. doi: 10.1038/leu.2013.337. Epub 2013 Nov 13. Review.

PMID:
24220273
[PubMed - indexed for MEDLINE]
12.

Inhibition of TET2-mediated conversion of 5-methylcytosine to 5-hydroxymethylcytosine disturbs erythroid and granulomonocytic differentiation of human hematopoietic progenitors.

Pronier E, Almire C, Mokrani H, Vasanthakumar A, Simon A, da Costa Reis Monte Mor B, Massé A, Le Couédic JP, Pendino F, Carbonne B, Larghero J, Ravanat JL, Casadevall N, Bernard OA, Droin N, Solary E, Godley LA, Vainchenker W, Plo I, Delhommeau F.

Blood. 2011 Sep 1;118(9):2551-5. doi: 10.1182/blood-2010-12-324707. Epub 2011 Jul 6.

PMID:
21734233
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Vitamin C induces Tet-dependent DNA demethylation and a blastocyst-like state in ES cells.

Blaschke K, Ebata KT, Karimi MM, Zepeda-Martínez JA, Goyal P, Mahapatra S, Tam A, Laird DJ, Hirst M, Rao A, Lorincz MC, Ramalho-Santos M.

Nature. 2013 Aug 8;500(7461):222-6. doi: 10.1038/nature12362. Epub 2013 Jun 30.

PMID:
23812591
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Mechanisms and functions of Tet protein-mediated 5-methylcytosine oxidation.

Wu H, Zhang Y.

Genes Dev. 2011 Dec 1;25(23):2436-52. doi: 10.1101/gad.179184.111. Review.

PMID:
22156206
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

TET enzymes, TDG and the dynamics of DNA demethylation.

Kohli RM, Zhang Y.

Nature. 2013 Oct 24;502(7472):472-9. doi: 10.1038/nature12750. Review.

PMID:
24153300
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Active DNA demethylation in post-mitotic neurons: a reason for optimism.

Gavin DP, Chase KA, Sharma RP.

Neuropharmacology. 2013 Dec;75:233-45. doi: 10.1016/j.neuropharm.2013.07.036. Epub 2013 Aug 16. Review.

PMID:
23958448
[PubMed - indexed for MEDLINE]
17.

Early-stage epigenetic modification during somatic cell reprogramming by Parp1 and Tet2.

Doege CA, Inoue K, Yamashita T, Rhee DB, Travis S, Fujita R, Guarnieri P, Bhagat G, Vanti WB, Shih A, Levine RL, Nik S, Chen EI, Abeliovich A.

Nature. 2012 Aug 30;488(7413):652-5. doi: 10.1038/nature11333.

PMID:
22902501
[PubMed - indexed for MEDLINE]
18.

TET2 gene expression and 5-hydroxymethylcytosine level in multiple sclerosis peripheral blood cells.

Calabrese R, Valentini E, Ciccarone F, Guastafierro T, Bacalini MG, Ricigliano VA, Zampieri M, Annibali V, Mechelli R, Franceschi C, Salvetti M, Caiafa P.

Biochim Biophys Acta. 2014 Jul;1842(7):1130-6. doi: 10.1016/j.bbadis.2014.04.010. Epub 2014 Apr 13.

PMID:
24735979
[PubMed - indexed for MEDLINE]
19.

5-Methylcytosine and 5-hydroxymethylcytosine spatiotemporal profiles in the mouse zygote.

Salvaing J, Aguirre-Lavin T, Boulesteix C, Lehmann G, Debey P, Beaujean N.

PLoS One. 2012;7(5):e38156. doi: 10.1371/journal.pone.0038156. Epub 2012 May 31.

PMID:
22693592
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Germline DNA demethylation dynamics and imprint erasure through 5-hydroxymethylcytosine.

Hackett JA, Sengupta R, Zylicz JJ, Murakami K, Lee C, Down TA, Surani MA.

Science. 2013 Jan 25;339(6118):448-52. doi: 10.1126/science.1229277. Epub 2012 Dec 6.

PMID:
23223451
[PubMed - indexed for MEDLINE]
Free PMC Article

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