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Results: 1 to 20 of 94

1.

p53 induces transcriptional and translational programs to suppress cell proliferation and growth.

Loayza-Puch F, Drost J, Rooijers K, Lopes R, Elkon R, Agami R.

Genome Biol. 2013 Apr 17;14(4):R32. doi: 10.1186/gb-2013-14-4-r32.

PMID:
23594524
[PubMed - in process]
Free PMC Article
2.

Depletion of ERK2 but not ERK1 abrogates oncogenic Ras-induced senescence.

Shin J, Yang J, Lee JC, Baek KH.

Cell Signal. 2013 Dec;25(12):2540-7. doi: 10.1016/j.cellsig.2013.08.014. Epub 2013 Aug 30.

PMID:
23993963
[PubMed - in process]
3.

Coordinate transcriptional and translational repression of p53 by TGF-β1 impairs the stress response.

López-Díaz FJ, Gascard P, Balakrishnan SK, Zhao J, Del Rincon SV, Spruck C, Tlsty TD, Emerson BM.

Mol Cell. 2013 May 23;50(4):552-64. doi: 10.1016/j.molcel.2013.04.029.

PMID:
23706820
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Oncogenic ras and p53 cooperate to induce cellular senescence.

Ferbeyre G, de Stanchina E, Lin AW, Querido E, McCurrach ME, Hannon GJ, Lowe SW.

Mol Cell Biol. 2002 May;22(10):3497-508.

PMID:
11971980
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

E3 ubiquitin ligase TRIM32 negatively regulates tumor suppressor p53 to promote tumorigenesis.

Liu J, Zhang C, Wang XL, Ly P, Belyi V, Xu-Monette ZY, Young KH, Hu W, Feng Z.

Cell Death Differ. 2014 Aug 22. doi: 10.1038/cdd.2014.121. [Epub ahead of print]

PMID:
25146927
[PubMed - as supplied by publisher]
6.

p53 regulation of the IGF-1/AKT/mTOR pathways and the endosomal compartment.

Feng Z.

Cold Spring Harb Perspect Biol. 2010 Feb;2(2):a001057. doi: 10.1101/cshperspect.a001057. Review.

PMID:
20182617
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

The p53 response element and transcriptional repression.

Wang B, Xiao Z, Ko HL, Ren EC.

Cell Cycle. 2010 Mar 1;9(5):870-9. Epub 2010 Mar 2. Review.

PMID:
20160511
[PubMed - indexed for MEDLINE]
Free Article
8.

The RAX/PACT-PKR stress response pathway promotes p53 sumoylation and activation, leading to G₁ arrest.

Bennett RL, Pan Y, Christian J, Hui T, May WS Jr.

Cell Cycle. 2012 Jan 15;11(2):407-17. doi: 10.4161/cc.11.2.18999. Epub 2012 Jan 15.

PMID:
22214662
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Hypoxia suppresses conversion from proliferative arrest to cellular senescence.

Leontieva OV, Natarajan V, Demidenko ZN, Burdelya LG, Gudkov AV, Blagosklonny MV.

Proc Natl Acad Sci U S A. 2012 Aug 14;109(33):13314-8. doi: 10.1073/pnas.1205690109. Epub 2012 Jul 30.

PMID:
22847439
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

A new twist in the feedback loop: stress-activated MDM2 destabilization is required for p53 activation.

Stommel JM, Wahl GM.

Cell Cycle. 2005 Mar;4(3):411-7. Epub 2005 Mar 2. Review.

PMID:
15684615
[PubMed - indexed for MEDLINE]
Free Article
12.

A new p53 target gene, RKIP, is essential for DNA damage-induced cellular senescence and suppression of ERK activation.

Lee SJ, Lee SH, Yoon MH, Park BJ.

Neoplasia. 2013 Jul;15(7):727-37.

PMID:
23814485
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Regulation of the G2/M transition by p53.

Taylor WR, Stark GR.

Oncogene. 2001 Apr 5;20(15):1803-15. Review.

PMID:
11313928
[PubMed - indexed for MEDLINE]
Free Article
14.

IGFBP-rP1 induces p21 expression through a p53-independent pathway, leading to cellular senescence of MCF-7 breast cancer cells.

Zuo S, Liu C, Wang J, Wang F, Xu W, Cui S, Yuan L, Chen X, Fan W, Cui M, Song G.

J Cancer Res Clin Oncol. 2012 Jun;138(6):1045-55. doi: 10.1007/s00432-012-1153-y. Epub 2012 Mar 6.

PMID:
22392074
[PubMed - indexed for MEDLINE]
15.

p53-mediated growth suppression in response to Nutlin-3 in cyclin D1 transformed cells occurs independently of p21.

Kan CE, Patton JT, Stark GR, Jackson MW.

Cancer Res. 2007 Oct 15;67(20):9862-8.

PMID:
17942917
[PubMed - indexed for MEDLINE]
Free Article
16.

C/EBPbeta cooperates with RB:E2F to implement Ras(V12)-induced cellular senescence.

Sebastian T, Malik R, Thomas S, Sage J, Johnson PF.

EMBO J. 2005 Sep 21;24(18):3301-12. Epub 2005 Aug 18.

PMID:
16107878
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

p53-directed translational control can shape and expand the universe of p53 target genes.

Zaccara S, Tebaldi T, Pederiva C, Ciribilli Y, Bisio A, Inga A.

Cell Death Differ. 2014 Oct;21(10):1522-34. doi: 10.1038/cdd.2014.79. Epub 2014 Jun 13.

PMID:
24926617
[PubMed - in process]
18.

Paradoxical suppression of cellular senescence by p53.

Demidenko ZN, Korotchkina LG, Gudkov AV, Blagosklonny MV.

Proc Natl Acad Sci U S A. 2010 May 25;107(21):9660-4. doi: 10.1073/pnas.1002298107. Epub 2010 May 10.

PMID:
20457898
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

AKT induces senescence in human cells via mTORC1 and p53 in the absence of DNA damage: implications for targeting mTOR during malignancy.

Astle MV, Hannan KM, Ng PY, Lee RS, George AJ, Hsu AK, Haupt Y, Hannan RD, Pearson RB.

Oncogene. 2012 Apr 12;31(15):1949-62. doi: 10.1038/onc.2011.394. Epub 2011 Sep 12.

PMID:
21909130
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Global genomic profiling reveals an extensive p53-regulated autophagy program contributing to key p53 responses.

Kenzelmann Broz D, Spano Mello S, Bieging KT, Jiang D, Dusek RL, Brady CA, Sidow A, Attardi LD.

Genes Dev. 2013 May 1;27(9):1016-31. doi: 10.1101/gad.212282.112.

PMID:
23651856
[PubMed - indexed for MEDLINE]
Free PMC Article

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