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Results: 1 to 20 of 106

1.

Pancreatic β-cell response to increased metabolic demand and to pharmacologic secretagogues requires EPAC2A.

Song WJ, Mondal P, Li Y, Lee SE, Hussain MA.

Diabetes. 2013 Aug;62(8):2796-807. doi: 10.2337/db12-1394. Epub 2013 Apr 11.

PMID:
23578994
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

SAD-A potentiates glucose-stimulated insulin secretion as a mediator of glucagon-like peptide 1 response in pancreatic β cells.

Nie J, Lilley BN, Pan YA, Faruque O, Liu X, Zhang W, Sanes JR, Han X, Shi Y.

Mol Cell Biol. 2013 Jul;33(13):2527-34. doi: 10.1128/MCB.00285-13. Epub 2013 Apr 29.

PMID:
23629625
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Cav1.2 and Cav1.3 are differentially coupled to glucagon-like peptide-1 potentiation of glucose-stimulated insulin secretion in the pancreatic beta-cell line INS-1.

Jacobo SM, Guerra ML, Hockerman GH.

J Pharmacol Exp Ther. 2009 Nov;331(2):724-32. doi: 10.1124/jpet.109.158519. Epub 2009 Aug 26.

PMID:
19710366
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Phospholipase C-ε links Epac2 activation to the potentiation of glucose-stimulated insulin secretion from mouse islets of Langerhans.

Dzhura I, Chepurny OG, Leech CA, Roe MW, Dzhura E, Xu X, Lu Y, Schwede F, Genieser HG, Smrcka AV, Holz GG.

Islets. 2011 May-Jun;3(3):121-8. Epub 2011 May 1.

PMID:
21478675
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Pancreas-specific Gsalpha deficiency has divergent effects on pancreatic alpha- and beta-cell proliferation.

Xie T, Chen M, Weinstein LS.

J Endocrinol. 2010 Sep;206(3):261-9. doi: 10.1677/JOE-10-0030. Epub 2010 Jun 11.

PMID:
20543009
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Critical role of the N-terminal cyclic AMP-binding domain of Epac2 in its subcellular localization and function.

Niimura M, Miki T, Shibasaki T, Fujimoto W, Iwanaga T, Seino S.

J Cell Physiol. 2009 Jun;219(3):652-8. doi: 10.1002/jcp.21709.

PMID:
19170062
[PubMed - indexed for MEDLINE]
7.

cAMP-mediated signaling normalizes glucose-stimulated insulin secretion in uncoupling protein-2 overexpressing beta-cells.

McQuaid TS, Saleh MC, Joseph JW, Gyulkhandanyan A, Manning-Fox JE, MacLellan JD, Wheeler MB, Chan CB.

J Endocrinol. 2006 Sep;190(3):669-80.

PMID:
17003268
[PubMed - indexed for MEDLINE]
Free Article
8.

Hormone-sensitive lipase has a role in lipid signaling for insulin secretion but is nonessential for the incretin action of glucagon-like peptide 1.

Peyot ML, Nolan CJ, Soni K, Joly E, Lussier R, Corkey BE, Wang SP, Mitchell GA, Prentki M.

Diabetes. 2004 Jul;53(7):1733-42.

PMID:
15220197
[PubMed - indexed for MEDLINE]
Free Article
9.

Exchange protein activated by cAMP 1 (Epac1)-deficient mice develop β-cell dysfunction and metabolic syndrome.

Kai AK, Lam AK, Chen Y, Tai AC, Zhang X, Lai AK, Yeung PK, Tam S, Wang J, Lam KS, Vanhoutte PM, Bos JL, Chung SS, Xu A, Chung SK.

FASEB J. 2013 Oct;27(10):4122-35. doi: 10.1096/fj.13-230433. Epub 2013 Jun 27.

PMID:
23825225
[PubMed - indexed for MEDLINE]
Free Article
10.

PKA-dependent potentiation of glucose-stimulated insulin secretion by Epac activator 8-pCPT-2'-O-Me-cAMP-AM in human islets of Langerhans.

Chepurny OG, Kelley GG, Dzhura I, Leech CA, Roe MW, Dzhura E, Li X, Schwede F, Genieser HG, Holz GG.

Am J Physiol Endocrinol Metab. 2010 Mar;298(3):E622-33. doi: 10.1152/ajpendo.00630.2009. Epub 2009 Dec 15.

PMID:
20009023
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Snapin mediates incretin action and augments glucose-dependent insulin secretion.

Song WJ, Seshadri M, Ashraf U, Mdluli T, Mondal P, Keil M, Azevedo M, Kirschner LS, Stratakis CA, Hussain MA.

Cell Metab. 2011 Mar 2;13(3):308-19. doi: 10.1016/j.cmet.2011.02.002.

PMID:
21356520
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Interleukin-6 enhances glucose-stimulated insulin secretion from pancreatic beta-cells: potential involvement of the PLC-IP3-dependent pathway.

Suzuki T, Imai J, Yamada T, Ishigaki Y, Kaneko K, Uno K, Hasegawa Y, Ishihara H, Oka Y, Katagiri H.

Diabetes. 2011 Feb;60(2):537-47. doi: 10.2337/db10-0796.

PMID:
21270264
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Epac2A makes a new impact in β-cell biology.

Holz GG, Chepurny OG, Leech CA.

Diabetes. 2013 Aug;62(8):2665-6. doi: 10.2337/db13-0796. No abstract available.

PMID:
23881198
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Differential importance of glucose-dependent insulinotropic polypeptide vs glucagon-like peptide 1 receptor signaling for beta cell survival in mice.

Maida A, Hansotia T, Longuet C, Seino Y, Drucker DJ.

Gastroenterology. 2009 Dec;137(6):2146-57. doi: 10.1053/j.gastro.2009.09.004. Epub 2009 Sep 17.

PMID:
19766644
[PubMed - indexed for MEDLINE]
15.

Effects of ghrelin on insulin and glucagon secretion: a study of isolated pancreatic islets and intact mice.

Salehi A, Dornonville de la Cour C, Håkanson R, Lundquist I.

Regul Pept. 2004 May 15;118(3):143-50.

PMID:
15003830
[PubMed - indexed for MEDLINE]
16.

Antidiabetic sulfonylureas and cAMP cooperatively activate Epac2A.

Takahashi T, Shibasaki T, Takahashi H, Sugawara K, Ono A, Inoue N, Furuya T, Seino S.

Sci Signal. 2013 Oct 22;6(298):ra94. doi: 10.1126/scisignal.2004581.

PMID:
24150255
[PubMed - indexed for MEDLINE]
17.

Role of Epac2A/Rap1 Signaling in Interplay Between Incretin and Sulfonylurea in Insulin Secretion.

Takahashi H, Shibasaki T, Park JH, Hidaka S, Takahashi T, Ono A, Song DK, Seino S.

Diabetes. 2014 Oct 14. pii: DB_140576. [Epub ahead of print]

PMID:
25315008
[PubMed - as supplied by publisher]
18.

Mechanism of prostacyclin-induced potentiation of glucose-induced insulin secretion.

Gurgul-Convey E, Hanzelka K, Lenzen S.

Endocrinology. 2012 Jun;153(6):2612-22. doi: 10.1210/en.2011-2027. Epub 2012 Apr 11.

PMID:
22495672
[PubMed - indexed for MEDLINE]
19.

Roles for corticotropin-releasing factor receptor type 1 in energy homeostasis in mice.

Sakamoto R, Matsubara E, Nomura M, Wang L, Kawahara Y, Yanase T, Nawata H, Takayanagi R.

Metabolism. 2013 Dec;62(12):1739-48. doi: 10.1016/j.metabol.2013.08.005. Epub 2013 Sep 17.

PMID:
24054833
[PubMed - indexed for MEDLINE]
20.

GPRC6A mediates the effects of L-arginine on insulin secretion in mouse pancreatic islets.

Pi M, Wu Y, Lenchik NI, Gerling I, Quarles LD.

Endocrinology. 2012 Oct;153(10):4608-15. Epub 2012 Aug 7.

PMID:
22872579
[PubMed - indexed for MEDLINE]
Free PMC Article

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