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Results: 1 to 20 of 119

1.

Genetic adaptation to high altitude in the Ethiopian highlands.

Scheinfeldt LB, Soi S, Thompson S, Ranciaro A, Woldemeskel D, Beggs W, Lambert C, Jarvis JP, Abate D, Belay G, Tishkoff SA.

Genome Biol. 2012 Jan 20;13(1):R1. doi: 10.1186/gb-2012-13-1-r1.

PMID:
22264333
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

The genetic architecture of adaptations to high altitude in Ethiopia.

Alkorta-Aranburu G, Beall CM, Witonsky DB, Gebremedhin A, Pritchard JK, Di Rienzo A.

PLoS Genet. 2012;8(12):e1003110. doi: 10.1371/journal.pgen.1003110. Epub 2012 Dec 6.

PMID:
23236293
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Andean and Tibetan patterns of adaptation to high altitude.

Bigham AW, Wilson MJ, Julian CG, Kiyamu M, Vargas E, Leon-Velarde F, Rivera-Chira M, Rodriquez C, Browne VA, Parra E, Brutsaert TD, Moore LG, Shriver MD.

Am J Hum Biol. 2013 Mar-Apr;25(2):190-7. doi: 10.1002/ajhb.22358. Epub 2013 Jan 24.

PMID:
23348729
[PubMed - indexed for MEDLINE]
4.

EPAS1 and EGLN1 associations with high altitude sickness in Han and Tibetan Chinese at the Qinghai-Tibetan Plateau.

Buroker NE, Ning XH, Zhou ZN, Li K, Cen WJ, Wu XF, Zhu WZ, Scott CR, Chen SH.

Blood Cells Mol Dis. 2012 Aug 15;49(2):67-73. doi: 10.1016/j.bcmd.2012.04.004. Epub 2012 May 15.

PMID:
22595196
[PubMed - indexed for MEDLINE]
5.

Identifying signatures of natural selection in Tibetan and Andean populations using dense genome scan data.

Bigham A, Bauchet M, Pinto D, Mao X, Akey JM, Mei R, Scherer SW, Julian CG, Wilson MJ, López Herráez D, Brutsaert T, Parra EJ, Moore LG, Shriver MD.

PLoS Genet. 2010 Sep 9;6(9):e1001116. doi: 10.1371/journal.pgen.1001116.

PMID:
20838600
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Genetic signatures reveal high-altitude adaptation in a set of ethiopian populations.

Huerta-Sánchez E, Degiorgio M, Pagani L, Tarekegn A, Ekong R, Antao T, Cardona A, Montgomery HE, Cavalleri GL, Robbins PA, Weale ME, Bradman N, Bekele E, Kivisild T, Tyler-Smith C, Nielsen R.

Mol Biol Evol. 2013 Aug;30(8):1877-88. doi: 10.1093/molbev/mst089. Epub 2013 May 10.

PMID:
23666210
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Genetic adaptation of the hypoxia-inducible factor pathway to oxygen pressure among eurasian human populations.

Ji LD, Qiu YQ, Xu J, Irwin DM, Tam SC, Tang NL, Zhang YP.

Mol Biol Evol. 2012 Nov;29(11):3359-70. doi: 10.1093/molbev/mss144. Epub 2012 May 23.

PMID:
22628534
[PubMed - indexed for MEDLINE]
Free Article
8.

Genetic determinants of Tibetan high-altitude adaptation.

Simonson TS, McClain DA, Jorde LB, Prchal JT.

Hum Genet. 2012 Apr;131(4):527-33. doi: 10.1007/s00439-011-1109-3. Epub 2011 Nov 9. Review.

PMID:
22068265
[PubMed - indexed for MEDLINE]
9.

Identification of a Tibetan-specific mutation in the hypoxic gene EGLN1 and its contribution to high-altitude adaptation.

Xiang K, Ouzhuluobu, Peng Y, Yang Z, Zhang X, Cui C, Zhang H, Li M, Zhang Y, Bianba, Gonggalanzi, Basang, Ciwangsangbu, Wu T, Chen H, Shi H, Qi X, Su B.

Mol Biol Evol. 2013 Aug;30(8):1889-98. doi: 10.1093/molbev/mst090. Epub 2013 May 10.

PMID:
23666208
[PubMed - indexed for MEDLINE]
Free Article
10.

Identifying positive selection candidate loci for high-altitude adaptation in Andean populations.

Bigham AW, Mao X, Mei R, Brutsaert T, Wilson MJ, Julian CG, Parra EJ, Akey JM, Moore LG, Shriver MD.

Hum Genomics. 2009 Dec;4(2):79-90.

PMID:
20038496
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Genetic variations in Tibetan populations and high-altitude adaptation at the Himalayas.

Peng Y, Yang Z, Zhang H, Cui C, Qi X, Luo X, Tao X, Wu T, Ouzhuluobu, Basang, Ciwangsangbu, Danzengduojie, Chen H, Shi H, Su B.

Mol Biol Evol. 2011 Feb;28(2):1075-81. doi: 10.1093/molbev/msq290. Epub 2010 Oct 28.

PMID:
21030426
[PubMed - indexed for MEDLINE]
Free Article
12.

Natural selection on EPAS1 (HIF2alpha) associated with low hemoglobin concentration in Tibetan highlanders.

Beall CM, Cavalleri GL, Deng L, Elston RC, Gao Y, Knight J, Li C, Li JC, Liang Y, McCormack M, Montgomery HE, Pan H, Robbins PA, Shianna KV, Tam SC, Tsering N, Veeramah KR, Wang W, Wangdui P, Weale ME, Xu Y, Xu Z, Yang L, Zaman MJ, Zeng C, Zhang L, Zhang X, Zhaxi P, Zheng YT.

Proc Natl Acad Sci U S A. 2010 Jun 22;107(25):11459-64. doi: 10.1073/pnas.1002443107. Epub 2010 Jun 7.

PMID:
20534544
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Metabolic insight into mechanisms of high-altitude adaptation in Tibetans.

Ge RL, Simonson TS, Cooksey RC, Tanna U, Qin G, Huff CD, Witherspoon DJ, Xing J, Zhengzhong B, Prchal JT, Jorde LB, McClain DA.

Mol Genet Metab. 2012 Jun;106(2):244-7. doi: 10.1016/j.ymgme.2012.03.003. Epub 2012 Mar 17.

PMID:
22503288
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Sequencing of 50 human exomes reveals adaptation to high altitude.

Yi X, Liang Y, Huerta-Sanchez E, Jin X, Cuo ZX, Pool JE, Xu X, Jiang H, Vinckenbosch N, Korneliussen TS, Zheng H, Liu T, He W, Li K, Luo R, Nie X, Wu H, Zhao M, Cao H, Zou J, Shan Y, Li S, Yang Q, Asan, Ni P, Tian G, Xu J, Liu X, Jiang T, Wu R, Zhou G, Tang M, Qin J, Wang T, Feng S, Li G, Huasang, Luosang J, Wang W, Chen F, Wang Y, Zheng X, Li Z, Bianba Z, Yang G, Wang X, Tang S, Gao G, Chen Y, Luo Z, Gusang L, Cao Z, Zhang Q, Ouyang W, Ren X, Liang H, Zheng H, Huang Y, Li J, Bolund L, Kristiansen K, Li Y, Zhang Y, Zhang X, Li R, Li S, Yang H, Nielsen R, Wang J, Wang J.

Science. 2010 Jul 2;329(5987):75-8. doi: 10.1126/science.1190371.

PMID:
20595611
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Genomic analysis of natural selection and phenotypic variation in high-altitude mongolians.

Xing J, Wuren T, Simonson TS, Watkins WS, Witherspoon DJ, Wu W, Qin G, Huff CD, Jorde LB, Ge RL.

PLoS Genet. 2013;9(7):e1003634. doi: 10.1371/journal.pgen.1003634. Epub 2013 Jul 18.

PMID:
23874230
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

A genome wide study of genetic adaptation to high altitude in feral Andean Horses of the páramo.

Hendrickson SL.

BMC Evol Biol. 2013 Dec 17;13:273. doi: 10.1186/1471-2148-13-273.

PMID:
24344830
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

A genome-wide search for signals of high-altitude adaptation in Tibetans.

Xu S, Li S, Yang Y, Tan J, Lou H, Jin W, Yang L, Pan X, Wang J, Shen Y, Wu B, Wang H, Jin L.

Mol Biol Evol. 2011 Feb;28(2):1003-11. doi: 10.1093/molbev/msq277. Epub 2010 Oct 20.

PMID:
20961960
[PubMed - indexed for MEDLINE]
Free Article
18.

Genetic adaptation to extreme hypoxia: study of high-altitude pulmonary edema in a three-generation Han Chinese family.

Lorenzo VF, Yang Y, Simonson TS, Nussenzveig R, Jorde LB, Prchal JT, Ge RL.

Blood Cells Mol Dis. 2009 Nov-Dec;43(3):221-5. doi: 10.1016/j.bcmd.2009.04.006. Epub 2009 May 29. Partial retraction in: Blood Cells Mol Dis. 2010 Mar 15;44(3):198.

PMID:
19481479
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

'ome on the Range: altitude adaptation, positive selection, and Himalayan genomics.

MacInnis MJ, Rupert JL.

High Alt Med Biol. 2011 Summer;12(2):133-9. doi: 10.1089/ham.2010.1090. Review.

PMID:
21718161
[PubMed - indexed for MEDLINE]
20.

Hemoglobin concentration of high-altitude Tibetans and Bolivian Aymara.

Beall CM, Brittenham GM, Strohl KP, Blangero J, Williams-Blangero S, Goldstein MC, Decker MJ, Vargas E, Villena M, Soria R, Alarcon AM, Gonzales C.

Am J Phys Anthropol. 1998 Jul;106(3):385-400. Erratum in: Am J Phys Anthropol 1998 Dec;107(4):421.

PMID:
9696153
[PubMed - indexed for MEDLINE]

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