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Results: 1 to 20 of 115

1.

Loss of the bloom syndrome helicase increases DNA ligase 4-independent genome rearrangements and tumorigenesis in aging Drosophila.

Garcia AM, Salomon RN, Witsell A, Liepkalns J, Calder RB, Lee M, Lundell M, Vijg J, McVey M.

Genome Biol. 2011 Dec 19;12(12):R121. doi: 10.1186/gb-2011-12-12-r121.

PMID:
22183041
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Multiple functions of Drosophila BLM helicase in maintenance of genome stability.

McVey M, Andersen SL, Broze Y, Sekelsky J.

Genetics. 2007 Aug;176(4):1979-92. Epub 2007 May 16.

PMID:
17507683
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Sources and structures of mitotic crossovers that arise when BLM helicase is absent in Drosophila.

LaFave MC, Andersen SL, Stoffregen EP, Holsclaw JK, Kohl KP, Overton LJ, Sekelsky J.

Genetics. 2014 Jan;196(1):107-18. doi: 10.1534/genetics.113.158618. Epub 2013 Oct 30.

PMID:
24172129
[PubMed - indexed for MEDLINE]
4.

Drosophila BLM in double-strand break repair by synthesis-dependent strand annealing.

Adams MD, McVey M, Sekelsky JJ.

Science. 2003 Jan 10;299(5604):265-7.

PMID:
12522255
[PubMed - indexed for MEDLINE]
Free Article
5.

Effect of Ku80 deficiency on mutation frequencies and spectra at a LacZ reporter locus in mouse tissues and cells.

Busuttil RA, Muñoz DP, Garcia AM, Rodier F, Kim WH, Suh Y, Hasty P, Campisi J, Vijg J.

PLoS One. 2008;3(10):e3458. doi: 10.1371/journal.pone.0003458. Epub 2008 Oct 20.

PMID:
18941635
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

In vivo analysis of Drosophila BLM helicase function during DNA double-strand gap repair.

McVey M.

Methods Mol Biol. 2010;587:185-94. doi: 10.1007/978-1-60327-355-8_13.

PMID:
20225150
[PubMed - indexed for MEDLINE]
7.

Depletion of the bloom syndrome helicase stimulates homology-dependent repair at double-strand breaks in human chromosomes.

Wang Y, Smith K, Waldman BC, Waldman AS.

DNA Repair (Amst). 2011 Apr 3;10(4):416-26. doi: 10.1016/j.dnarep.2011.01.009.

PMID:
21300576
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Template disruptions and failure of double Holliday junction dissolution during double-strand break repair in Drosophila BLM mutants.

Johnson-Schlitz D, Engels WR.

Proc Natl Acad Sci U S A. 2006 Nov 7;103(45):16840-5. Epub 2006 Oct 30.

PMID:
17075047
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

End-joining repair of double-strand breaks in Drosophila melanogaster is largely DNA ligase IV independent.

McVey M, Radut D, Sekelsky JJ.

Genetics. 2004 Dec;168(4):2067-76.

PMID:
15611176
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Myc-dependent genome instability and lifespan in Drosophila.

Greer C, Lee M, Westerhof M, Milholland B, Spokony R, Vijg J, Secombe J.

PLoS One. 2013 Sep 6;8(9):e74641. doi: 10.1371/journal.pone.0074641. eCollection 2013.

PMID:
24040302
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Genetic interactions between BLM and DNA ligase IV in human cells.

So S, Adachi N, Lieber MR, Koyama H.

J Biol Chem. 2004 Dec 31;279(53):55433-42. Epub 2004 Oct 26.

PMID:
15509577
[PubMed - indexed for MEDLINE]
Free Article
12.

Three structure-selective endonucleases are essential in the absence of BLM helicase in Drosophila.

Andersen SL, Kuo HK, Savukoski D, Brodsky MH, Sekelsky J.

PLoS Genet. 2011 Oct;7(10):e1002315. doi: 10.1371/journal.pgen.1002315. Epub 2011 Oct 13.

PMID:
22022278
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Dual roles for DNA polymerase theta in alternative end-joining repair of double-strand breaks in Drosophila.

Chan SH, Yu AM, McVey M.

PLoS Genet. 2010 Jul 1;6(7):e1001005. doi: 10.1371/journal.pgen.1001005.

PMID:
20617203
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Drosophila bloom helicase maintains genome integrity by inhibiting recombination between divergent DNA sequences.

Kappeler M, Kranz E, Woolcock K, Georgiev O, Schaffner W.

Nucleic Acids Res. 2008 Dec;36(21):6907-17. doi: 10.1093/nar/gkn793. Epub 2008 Oct 31.

PMID:
18978019
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Formation of deletions during double-strand break repair in Drosophila DmBlm mutants occurs after strand invasion.

McVey M, Larocque JR, Adams MD, Sekelsky JJ.

Proc Natl Acad Sci U S A. 2004 Nov 2;101(44):15694-9. Epub 2004 Oct 22.

PMID:
15501916
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Removal of the bloom syndrome DNA helicase extends the utility of imprecise transposon excision for making null mutations in Drosophila.

Witsell A, Kane DP, Rubin S, McVey M.

Genetics. 2009 Nov;183(3):1187-93. doi: 10.1534/genetics.109.108472. Epub 2009 Aug 17.

PMID:
19687136
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Interplay between Drosophila Bloom's syndrome helicase and Ku autoantigen during nonhomologous end joining repair of P element-induced DNA breaks.

Min B, Weinert BT, Rio DC.

Proc Natl Acad Sci U S A. 2004 Jun 15;101(24):8906-11. Epub 2004 Jun 7.

PMID:
15184650
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Human Bloom protein stimulates flap endonuclease 1 activity by resolving DNA secondary structure.

Wang W, Bambara RA.

J Biol Chem. 2005 Feb 18;280(7):5391-9. Epub 2004 Dec 4.

PMID:
15579905
[PubMed - indexed for MEDLINE]
Free Article
19.

The C-terminal domain of the Bloom syndrome DNA helicase is essential for genomic stability.

Yankiwski V, Noonan JP, Neff NF.

BMC Cell Biol. 2001;2:11. Epub 2001 Jul 2.

PMID:
11472631
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Bloom DNA helicase facilitates homologous recombination between diverged homologous sequences.

Kikuchi K, Abdel-Aziz HI, Taniguchi Y, Yamazoe M, Takeda S, Hirota K.

J Biol Chem. 2009 Sep 25;284(39):26360-7. doi: 10.1074/jbc.M109.029348. Epub 2009 Aug 5.

PMID:
19661064
[PubMed - indexed for MEDLINE]
Free PMC Article

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