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Results: 1 to 20 of 120

1.

The rhomboid protease family: a decade of progress on function and mechanism.

Urban S, Dickey SW.

Genome Biol. 2011 Oct 27;12(10):231. doi: 10.1186/gb-2011-12-10-231. Review.

PMID:
22035660
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Structure and mechanism of rhomboid protease.

Ha Y, Akiyama Y, Xue Y.

J Biol Chem. 2013 May 31;288(22):15430-6. doi: 10.1074/jbc.R112.422378. Epub 2013 Apr 12. Review.

PMID:
23585569
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Untangling structure-function relationships in the rhomboid family of intramembrane proteases.

Brooks CL, Lemieux MJ.

Biochim Biophys Acta. 2013 Dec;1828(12):2862-72. doi: 10.1016/j.bbamem.2013.05.003. Review.

PMID:
24099005
[PubMed - indexed for MEDLINE]
4.

Structural analysis of a rhomboid family intramembrane protease reveals a gating mechanism for substrate entry.

Wu Z, Yan N, Feng L, Oberstein A, Yan H, Baker RP, Gu L, Jeffrey PD, Urban S, Shi Y.

Nat Struct Mol Biol. 2006 Dec;13(12):1084-91. Epub 2006 Nov 10.

PMID:
17099694
[PubMed - indexed for MEDLINE]
5.

Crystal structure of a rhomboid family intramembrane protease.

Wang Y, Zhang Y, Ha Y.

Nature. 2006 Nov 9;444(7116):179-80. Epub 2006 Oct 11.

PMID:
17051161
[PubMed - indexed for MEDLINE]
6.

Large lateral movement of transmembrane helix S5 is not required for substrate access to the active site of rhomboid intramembrane protease.

Xue Y, Ha Y.

J Biol Chem. 2013 Jun 7;288(23):16645-54. doi: 10.1074/jbc.M112.438127. Epub 2013 Apr 22.

PMID:
23609444
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

In vivo analysis reveals substrate-gating mutants of a rhomboid intramembrane protease display increased activity in living cells.

Urban S, Baker RP.

Biol Chem. 2008 Aug;389(8):1107-15. doi: 10.1515/BC.2008.122.

PMID:
18979634
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

An internal water-retention site in the rhomboid intramembrane protease GlpG ensures catalytic efficiency.

Zhou Y, Moin SM, Urban S, Zhang Y.

Structure. 2012 Jul 3;20(7):1255-63. doi: 10.1016/j.str.2012.04.022. Epub 2012 Jun 14.

PMID:
22705210
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Structural basis for intramembrane proteolysis by rhomboid serine proteases.

Ben-Shem A, Fass D, Bibi E.

Proc Natl Acad Sci U S A. 2007 Jan 9;104(2):462-6. Epub 2006 Dec 26.

PMID:
17190827
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Reconstitution of intramembrane proteolysis in vitro reveals that pure rhomboid is sufficient for catalysis and specificity.

Urban S, Wolfe MS.

Proc Natl Acad Sci U S A. 2005 Feb 8;102(6):1883-8. Epub 2005 Jan 31.

PMID:
15684070
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Oligomeric state study of prokaryotic rhomboid proteases.

Sampathkumar P, Mak MW, Fischer-Witholt SJ, Guigard E, Kay CM, Lemieux MJ.

Biochim Biophys Acta. 2012 Dec;1818(12):3090-7. doi: 10.1016/j.bbamem.2012.08.004. Epub 2012 Aug 18.

PMID:
22921757
[PubMed - indexed for MEDLINE]
Free Article
12.

Role of rhomboid proteases in bacteria.

Rather P.

Biochim Biophys Acta. 2013 Dec;1828(12):2849-54. doi: 10.1016/j.bbamem.2013.03.012. Epub 2013 Mar 18. Review.

PMID:
23518036
[PubMed - indexed for MEDLINE]
13.

The structural basis for catalysis and substrate specificity of a rhomboid protease.

Vinothkumar KR, Strisovsky K, Andreeva A, Christova Y, Verhelst S, Freeman M.

EMBO J. 2010 Nov 17;29(22):3797-809. doi: 10.1038/emboj.2010.243. Epub 2010 Oct 1.

PMID:
20890268
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Proteolytic action of GlpG, a rhomboid protease in the Escherichia coli cytoplasmic membrane.

Maegawa S, Ito K, Akiyama Y.

Biochemistry. 2005 Oct 18;44(41):13543-52.

PMID:
16216077
[PubMed - indexed for MEDLINE]
15.

The rhomboids: a nearly ubiquitous family of intramembrane serine proteases that probably evolved by multiple ancient horizontal gene transfers.

Koonin EV, Makarova KS, Rogozin IB, Davidovic L, Letellier MC, Pellegrini L.

Genome Biol. 2003;4(3):R19. Epub 2003 Feb 28.

PMID:
12620104
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Enzymatic analysis of a rhomboid intramembrane protease implicates transmembrane helix 5 as the lateral substrate gate.

Baker RP, Young K, Feng L, Shi Y, Urban S.

Proc Natl Acad Sci U S A. 2007 May 15;104(20):8257-62. Epub 2007 Apr 26.

PMID:
17463085
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Emerging role of rhomboid family proteins in mammalian biology and disease.

Bergbold N, Lemberg MK.

Biochim Biophys Acta. 2013 Dec;1828(12):2840-8. doi: 10.1016/j.bbamem.2013.03.025. Epub 2013 Apr 3. Review.

PMID:
23562403
[PubMed - indexed for MEDLINE]
18.

New insights into parasite rhomboid proteases.

M Santos J, Graindorge A, Soldati-Favre D.

Mol Biochem Parasitol. 2012 Mar-Apr;182(1-2):27-36. doi: 10.1016/j.molbiopara.2011.11.010. Epub 2011 Dec 7. Review.

PMID:
22173057
[PubMed - indexed for MEDLINE]
19.

The intramembrane active site of GlpG, an E. coli rhomboid protease, is accessible to water and hydrolyses an extramembrane peptide bond of substrates.

Maegawa S, Koide K, Ito K, Akiyama Y.

Mol Microbiol. 2007 Apr;64(2):435-47.

PMID:
17493126
[PubMed - indexed for MEDLINE]
20.

Sequence features of substrates required for cleavage by GlpG, an Escherichia coli rhomboid protease.

Akiyama Y, Maegawa S.

Mol Microbiol. 2007 May;64(4):1028-37.

PMID:
17501925
[PubMed - indexed for MEDLINE]

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