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Results: 1 to 20 of 170

1.

Chromothripsis is a common mechanism driving genomic rearrangements in primary and metastatic colorectal cancer.

Kloosterman WP, Hoogstraat M, Paling O, Tavakoli-Yaraki M, Renkens I, Vermaat JS, van Roosmalen MJ, van Lieshout S, Nijman IJ, Roessingh W, van 't Slot R, van de Belt J, Guryev V, Koudijs M, Voest E, Cuppen E.

Genome Biol. 2011 Oct 19;12(10):R103. doi: 10.1186/gb-2011-12-10-r103.

PMID:
22014273
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Chromothripsis as a mechanism driving complex de novo structural rearrangements in the germline.

Kloosterman WP, Guryev V, van Roosmalen M, Duran KJ, de Bruijn E, Bakker SC, Letteboer T, van Nesselrooij B, Hochstenbach R, Poot M, Cuppen E.

Hum Mol Genet. 2011 May 15;20(10):1916-24. doi: 10.1093/hmg/ddr073. Epub 2011 Feb 24.

PMID:
21349919
[PubMed - indexed for MEDLINE]
Free Article
3.

Breakpoint profiling of 64 cancer genomes reveals numerous complex rearrangements spawned by homology-independent mechanisms.

Malhotra A, Lindberg M, Faust GG, Leibowitz ML, Clark RA, Layer RM, Quinlan AR, Hall IM.

Genome Res. 2013 May;23(5):762-76. doi: 10.1101/gr.143677.112. Epub 2013 Feb 14.

PMID:
23410887
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Unique genetic profile of sporadic colorectal cancer liver metastasis versus primary tumors as defined by high-density single-nucleotide polymorphism arrays.

Muñoz-Bellvis L, Fontanillo C, González-González M, Garcia E, Iglesias M, Esteban C, Gutierrez ML, Abad MM, Bengoechea O, De Las Rivas J, Orfao A, Sayagués JM.

Mod Pathol. 2012 Apr;25(4):590-601. doi: 10.1038/modpathol.2011.195. Epub 2012 Jan 6.

PMID:
22222638
[PubMed - indexed for MEDLINE]
Free Article
5.

Prevalence and clinical implications of chromothripsis in cancer genomes.

Kloosterman WP, Koster J, Molenaar JJ.

Curr Opin Oncol. 2014 Jan;26(1):64-72. doi: 10.1097/CCO.0000000000000038. Review.

PMID:
24305569
[PubMed - indexed for MEDLINE]
6.

Chromothripsis and cancer: causes and consequences of chromosome shattering.

Forment JV, Kaidi A, Jackson SP.

Nat Rev Cancer. 2012 Oct;12(10):663-70. doi: 10.1038/nrc3352. Epub 2012 Sep 13. Review.

PMID:
22972457
[PubMed - indexed for MEDLINE]
7.

Breakpoint features of genomic rearrangements in neuroblastoma with unbalanced translocations and chromothripsis.

Boeva V, Jouannet S, Daveau R, Combaret V, Pierre-Eugène C, Cazes A, Louis-Brennetot C, Schleiermacher G, Ferrand S, Pierron G, Lermine A, Rio Frio T, Raynal V, Vassal G, Barillot E, Delattre O, Janoueix-Lerosey I.

PLoS One. 2013 Aug 26;8(8):e72182. doi: 10.1371/journal.pone.0072182. eCollection 2013.

PMID:
23991058
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Constitutional chromothripsis rearrangements involve clustered double-stranded DNA breaks and nonhomologous repair mechanisms.

Kloosterman WP, Tavakoli-Yaraki M, van Roosmalen MJ, van Binsbergen E, Renkens I, Duran K, Ballarati L, Vergult S, Giardino D, Hansson K, Ruivenkamp CA, Jager M, van Haeringen A, Ippel EF, Haaf T, Passarge E, Hochstenbach R, Menten B, Larizza L, Guryev V, Poot M, Cuppen E.

Cell Rep. 2012 Jun 28;1(6):648-55. doi: 10.1016/j.celrep.2012.05.009. Epub 2012 Jun 15.

PMID:
22813740
[PubMed - indexed for MEDLINE]
Free Article
9.

Specific genomic aberrations in primary colorectal cancer are associated with liver metastases.

Bruin SC, Klijn C, Liefers GJ, Braaf LM, Joosse SA, van Beers EH, Verwaal VJ, Morreau H, Wessels LF, van Velthuysen ML, Tollenaar RA, Van't Veer LJ.

BMC Cancer. 2010 Dec 2;10:662. doi: 10.1186/1471-2407-10-662.

PMID:
21126340
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Chromosome arm 20q gains and other genomic alterations in colorectal cancer metastatic to liver, as analyzed by comparative genomic hybridization and fluorescence in situ hybridization.

Korn WM, Yasutake T, Kuo WL, Warren RS, Collins C, Tomita M, Gray J, Waldman FM.

Genes Chromosomes Cancer. 1999 Jun;25(2):82-90.

PMID:
10337990
[PubMed - indexed for MEDLINE]
11.

SMAD4 mutations in colorectal cancer probably occur before chromosomal instability, but after divergence of the microsatellite instability pathway.

Woodford-Richens KL, Rowan AJ, Gorman P, Halford S, Bicknell DC, Wasan HS, Roylance RR, Bodmer WF, Tomlinson IP.

Proc Natl Acad Sci U S A. 2001 Aug 14;98(17):9719-23. Epub 2001 Jul 31.

PMID:
11481457
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Relationship of gene expression and chromosomal abnormalities in colorectal cancer.

Tsafrir D, Bacolod M, Selvanayagam Z, Tsafrir I, Shia J, Zeng Z, Liu H, Krier C, Stengel RF, Barany F, Gerald WL, Paty PB, Domany E, Notterman DA.

Cancer Res. 2006 Feb 15;66(4):2129-37.

PMID:
16489013
[PubMed - indexed for MEDLINE]
Free Article
13.

Chromothripsis-like patterns are recurring but heterogeneously distributed features in a survey of 22,347 cancer genome screens.

Cai H, Kumar N, Bagheri HC, von Mering C, Robinson MD, Baudis M.

BMC Genomics. 2014 Jan 29;15:82. doi: 10.1186/1471-2164-15-82.

PMID:
24476156
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Chromothripsis under the microscope: a cytogenetic perspective of two cases of AML with catastrophic chromosome rearrangement.

Mackinnon RN, Campbell LJ.

Cancer Genet. 2013 Jun;206(6):238-51. doi: 10.1016/j.cancergen.2013.05.021. Epub 2013 Aug 2.

PMID:
23911237
[PubMed - indexed for MEDLINE]
15.

Identification of chromosomal aberrations of metastatic potential in colorectal carcinoma.

Yamamoto S, Midorikawa Y, Morikawa T, Nishimura Y, Sakamoto H, Ishikawa S, Akagi K, Aburatani H.

Genes Chromosomes Cancer. 2010 May;49(5):487-96. doi: 10.1002/gcc.20759.

PMID:
20175194
[PubMed - indexed for MEDLINE]
16.

Colorectal cancer cell lines are representative models of the main molecular subtypes of primary cancer.

Mouradov D, Sloggett C, Jorissen RN, Love CG, Li S, Burgess AW, Arango D, Strausberg RL, Buchanan D, Wormald S, O'Connor L, Wilding JL, Bicknell D, Tomlinson IP, Bodmer WF, Mariadason JM, Sieber OM.

Cancer Res. 2014 Jun 15;74(12):3238-47. doi: 10.1158/0008-5472.CAN-14-0013. Epub 2014 Apr 22.

PMID:
24755471
[PubMed - indexed for MEDLINE]
17.

Genetic changes in colorectal carcinoma tumors with liver metastases analyzed by comparative genomic hybridization and DNA ploidy.

Nakao K, Shibusawa M, Ishihara A, Yoshizawa H, Tsunoda A, Kusano M, Kurose A, Makita T, Sasaki K.

Cancer. 2001 Feb 15;91(4):721-6.

PMID:
11241239
[PubMed - indexed for MEDLINE]
18.

Gene fusions by chromothripsis of chromosome 5q in the VCaP prostate cancer cell line.

Teles Alves I, Hiltemann S, Hartjes T, van der Spek P, Stubbs A, Trapman J, Jenster G.

Hum Genet. 2013 Jun;132(6):709-13. doi: 10.1007/s00439-013-1308-1. Epub 2013 Apr 25.

PMID:
23615946
[PubMed - indexed for MEDLINE]
19.

Metastatic susceptibility locus, an 8p hot-spot for tumour progression disrupted in colorectal liver metastases: 13 candidate genes examined at the DNA, mRNA and protein level.

Macartney-Coxson DP, Hood KA, Shi HJ, Ward T, Wiles A, O'Connor R, Hall DA, Lea RA, Royds JA, Stubbs RS, Rooker S.

BMC Cancer. 2008 Jul 1;8:187. doi: 10.1186/1471-2407-8-187.

PMID:
18590575
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Complex tumor genomes inferred from single circulating tumor cells by array-CGH and next-generation sequencing.

Heitzer E, Auer M, Gasch C, Pichler M, Ulz P, Hoffmann EM, Lax S, Waldispuehl-Geigl J, Mauermann O, Lackner C, Höfler G, Eisner F, Sill H, Samonigg H, Pantel K, Riethdorf S, Bauernhofer T, Geigl JB, Speicher MR.

Cancer Res. 2013 May 15;73(10):2965-75. doi: 10.1158/0008-5472.CAN-12-4140. Epub 2013 Mar 7.

PMID:
23471846
[PubMed - indexed for MEDLINE]
Free Article

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