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Results: 1 to 20 of 106

1.

Exome sequencing identifies a missense mutation in Isl1 associated with low penetrance otitis media in dearisch mice.

Hilton JM, Lewis MA, Grati M, Ingham N, Pearson S, Laskowski RA, Adams DJ, Steel KP.

Genome Biol. 2011 Sep 21;12(9):R90. doi: 10.1186/gb-2011-12-9-r90.

PMID:
21936904
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Mutation at the Evi1 locus in Junbo mice causes susceptibility to otitis media.

Parkinson N, Hardisty-Hughes RE, Tateossian H, Tsai HT, Brooker D, Morse S, Lalane Z, MacKenzie F, Fray M, Glenister P, Woodward AM, Polley S, Barbaric I, Dear N, Hough TA, Hunter AJ, Cheeseman MT, Brown SD.

PLoS Genet. 2006 Oct 6;2(10):e149.

PMID:
17029558
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Hair cell overexpression of Islet1 reduces age-related and noise-induced hearing loss.

Huang M, Kantardzhieva A, Scheffer D, Liberman MC, Chen ZY.

J Neurosci. 2013 Sep 18;33(38):15086-94. doi: 10.1523/JNEUROSCI.1489-13.2013.

PMID:
24048839
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

C3H/HeJ mouse model for spontaneous chronic otitis media.

MacArthur CJ, Hefeneider SH, Kempton JB, Trune DR.

Laryngoscope. 2006 Jul;116(7):1071-9. Erratum in: Laryngoscope. 2006 Nov;116(11):2098.

PMID:
16826039
[PubMed - indexed for MEDLINE]
5.

Mcph1-deficient mice reveal a role for MCPH1 in otitis media.

Chen J, Ingham N, Clare S, Raisen C, Vancollie VE, Ismail O, McIntyre RE, Tsang SH, Mahajan VB, Dougan G, Adams DJ, White JK, Steel KP.

PLoS One. 2013;8(3):e58156. doi: 10.1371/journal.pone.0058156. Epub 2013 Mar 13.

PMID:
23516444
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Otitis media in the Tgif knockout mouse implicates TGFβ signalling in chronic middle ear inflammatory disease.

Tateossian H, Morse S, Parker A, Mburu P, Warr N, Acevedo-Arozena A, Cheeseman M, Wells S, Brown SD.

Hum Mol Genet. 2013 Jul 1;22(13):2553-65. doi: 10.1093/hmg/ddt103. Epub 2013 Mar 3.

PMID:
23459932
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

The homeobox gene Emx2 underlies middle ear and inner ear defects in the deaf mouse mutant pardon.

Rhodes CR, Parkinson N, Tsai H, Brooker D, Mansell S, Spurr N, Hunter AJ, Steel KP, Brown SD.

J Neurocytol. 2003 Nov;32(9):1143-54.

PMID:
15044845
[PubMed - indexed for MEDLINE]
8.

Massively parallel sequencing of the mouse exome to accurately identify rare, induced mutations: an immediate source for thousands of new mouse models.

Andrews TD, Whittle B, Field MA, Balakishnan B, Zhang Y, Shao Y, Cho V, Kirk M, Singh M, Xia Y, Hager J, Winslade S, Sjollema G, Beutler B, Enders A, Goodnow CC.

Open Biol. 2012 May;2(5):120061. doi: 10.1098/rsob.120061.

PMID:
22724066
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Ectopic mineralization in the middle ear and chronic otitis media with effusion caused by RPL38 deficiency in the Tail-short (Ts) mouse.

Noben-Trauth K, Latoche JR.

J Biol Chem. 2011 Jan 28;286(4):3079-93. doi: 10.1074/jbc.M110.184598. Epub 2010 Nov 9.

PMID:
21062742
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Otitis media in a new mouse model for CHARGE syndrome with a deletion in the Chd7 gene.

Tian C, Yu H, Yang B, Han F, Zheng Y, Bartels CF, Schelling D, Arnold JE, Scacheri PC, Zheng QY.

PLoS One. 2012;7(4):e34944. doi: 10.1371/journal.pone.0034944. Epub 2012 Apr 23.

PMID:
22539951
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

A novel model of spontaneous otitis media with effusion (OME) in the Oxgr1 knock-out mouse.

Kerschner JE, Hong W, Taylor SR, Kerschner JA, Khampang P, Wrege KC, North PE.

Int J Pediatr Otorhinolaryngol. 2013 Jan;77(1):79-84. doi: 10.1016/j.ijporl.2012.09.037. Epub 2012 Nov 30.

PMID:
23200873
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

A missense mutation in the conserved C2B domain of otoferlin causes deafness in a new mouse model of DFNB9.

Longo-Guess C, Gagnon LH, Bergstrom DE, Johnson KR.

Hear Res. 2007 Dec;234(1-2):21-8. Epub 2007 Sep 29.

PMID:
17967520
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Mutation in Phex gene predisposes BALB/c-Phex(Hyp-Duk)/Y mice to otitis media.

Han F, Yu H, Li P, Zhang J, Tian C, Li H, Zheng QY.

PLoS One. 2012;7(9):e43010. doi: 10.1371/journal.pone.0043010. Epub 2012 Sep 28.

PMID:
23028440
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Secondary variants in individuals undergoing exome sequencing: screening of 572 individuals identifies high-penetrance mutations in cancer-susceptibility genes.

Johnston JJ, Rubinstein WS, Facio FM, Ng D, Singh LN, Teer JK, Mullikin JC, Biesecker LG.

Am J Hum Genet. 2012 Jul 13;91(1):97-108. doi: 10.1016/j.ajhg.2012.05.021. Epub 2012 Jun 14.

PMID:
22703879
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Sh3pxd2b mice are a model for craniofacial dysmorphology and otitis media.

Yang B, Tian C, Zhang ZG, Han FC, Azem R, Yu H, Zheng Y, Jin G, Arnold JE, Zheng QY.

PLoS One. 2011;6(7):e22622. doi: 10.1371/journal.pone.0022622. Epub 2011 Jul 27.

PMID:
21818352
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Otitis media incidence and impact on the auditory brain stem response in lipopolysaccharide-nonresponsive C3H/HeJ mice.

Mitchell CR, Kempton JB, Scott-Tyler B, Trune DR.

Otolaryngol Head Neck Surg. 1997 Nov;117(5):459-64.

PMID:
9374167
[PubMed - indexed for MEDLINE]
17.

Evaluation of the mouse model for acute otitis media.

MacArthur CJ, Hefeneider SH, Kempton JB, Parrish SK, McCoy SL, Trune DR.

Hear Res. 2006 Sep;219(1-2):12-23. Epub 2006 Aug 2.

PMID:
16887307
[PubMed - indexed for MEDLINE]
18.

A novel genetic variant in the transcription factor Islet-1 exerts gain of function on myocyte enhancer factor 2C promoter activity.

Friedrich FW, Dilanian G, Khattar P, Juhr D, Gueneau L, Charron P, Fressart V, Vilquin JT, Isnard R, Gouya L, Richard P, Hammoudi N, Komajda M, Bonne G, Eschenhagen T, Dubourg O, Villard E, Carrier L.

Eur J Heart Fail. 2013 Mar;15(3):267-76. doi: 10.1093/eurjhf/hfs178. Epub 2012 Nov 14.

PMID:
23152444
[PubMed - indexed for MEDLINE]
19.

Mutanlallemand (mtl) and Belly Spot and Deafness (bsd) are two new mutations of Lmx1a causing severe cochlear and vestibular defects.

Steffes G, Lorente-Cánovas B, Pearson S, Brooker RH, Spiden S, Kiernan AE, Guénet JL, Steel KP.

PLoS One. 2012;7(11):e51065. doi: 10.1371/journal.pone.0051065. Epub 2012 Nov 30.

PMID:
23226461
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Otitis media impacts hundreds of mouse middle and inner ear genes.

MacArthur CJ, Hausman F, Kempton JB, Choi D, Trune DR.

PLoS One. 2013 Oct 4;8(10):e75213. doi: 10.1371/journal.pone.0075213. eCollection 2013.

PMID:
24124478
[PubMed - indexed for MEDLINE]
Free PMC Article

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