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Results: 1 to 20 of 100

1.

Systematic analysis of genome-wide fitness data in yeast reveals novel gene function and drug action.

Hillenmeyer ME, Ericson E, Davis RW, Nislow C, Koller D, Giaever G.

Genome Biol. 2010;11(3):R30. doi: 10.1186/gb-2010-11-3-r30. Epub 2010 Mar 12.

PMID:
20226027
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Screening the budding yeast genome reveals unique factors affecting K2 toxin susceptibility.

Servienė E, Lukša J, Orentaitė I, Lafontaine DL, Urbonavičius J.

PLoS One. 2012;7(12):e50779. doi: 10.1371/journal.pone.0050779. Epub 2012 Dec 5.

PMID:
23227207
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Off-target effects of psychoactive drugs revealed by genome-wide assays in yeast.

Ericson E, Gebbia M, Heisler LE, Wildenhain J, Tyers M, Giaever G, Nislow C.

PLoS Genet. 2008 Aug 8;4(8):e1000151. doi: 10.1371/journal.pgen.1000151.

PMID:
18688276
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

An integrated platform of genomic assays reveals small-molecule bioactivities.

Hoon S, Smith AM, Wallace IM, Suresh S, Miranda M, Fung E, Proctor M, Shokat KM, Zhang C, Davis RW, Giaever G, St Onge RP, Nislow C.

Nat Chem Biol. 2008 Aug;4(8):498-506. doi: 10.1038/nchembio.100. Epub 2008 Jul 11. Erratum in: Nat Chem Biol.2008 Oct;4(10):632.. StOnge, Robert P [corrected to St Onge,Robert P].

PMID:
18622389
[PubMed - indexed for MEDLINE]
5.

Chemogenomic approaches to elucidation of gene function and genetic pathways.

Pierce SE, Davis RW, Nislow C, Giaever G.

Methods Mol Biol. 2009;548:115-43. doi: 10.1007/978-1-59745-540-4_7.

PMID:
19521822
[PubMed - indexed for MEDLINE]
6.

Experimental genomics of fitness in yeast.

Bell G.

Proc Biol Sci. 2010 May 22;277(1687):1459-67. doi: 10.1098/rspb.2009.2099. Epub 2010 Feb 3. Review.

PMID:
20129976
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

The chemical genomic portrait of yeast: uncovering a phenotype for all genes.

Hillenmeyer ME, Fung E, Wildenhain J, Pierce SE, Hoon S, Lee W, Proctor M, St Onge RP, Tyers M, Koller D, Altman RB, Davis RW, Nislow C, Giaever G.

Science. 2008 Apr 18;320(5874):362-5. doi: 10.1126/science.1150021.

PMID:
18420932
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Combining chemical genomics screens in yeast to reveal spectrum of effects of chemical inhibition of sphingolipid biosynthesis.

Kemmer D, McHardy LM, Hoon S, Rebérioux D, Giaever G, Nislow C, Roskelley CD, Roberge M.

BMC Microbiol. 2009 Jan 14;9:9. doi: 10.1186/1471-2180-9-9.

PMID:
19144191
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Genome-wide analysis of barcoded Saccharomyces cerevisiae gene-deletion mutants in pooled cultures.

Pierce SE, Davis RW, Nislow C, Giaever G.

Nat Protoc. 2007;2(11):2958-74.

PMID:
18007632
[PubMed - indexed for MEDLINE]
10.

A genome-wide deletion mutant screen identifies pathways affected by nickel sulfate in Saccharomyces cerevisiae.

Arita A, Zhou X, Ellen TP, Liu X, Bai J, Rooney JP, Kurtz A, Klein CB, Dai W, Begley TJ, Costa M.

BMC Genomics. 2009 Nov 15;10:524. doi: 10.1186/1471-2164-10-524.

PMID:
19917080
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Genome-wide identification of genes required for yeast growth under imatinib stress: vacuolar H+-ATPase function is an important target of this anticancer drug.

dos Santos SC, Sá-Correia I.

OMICS. 2009 Jun;13(3):185-98. doi: 10.1089/omi.2008.0086.

PMID:
19260806
[PubMed - indexed for MEDLINE]
12.

Navigating the chaperone network: an integrative map of physical and genetic interactions mediated by the hsp90 chaperone.

Zhao R, Davey M, Hsu YC, Kaplanek P, Tong A, Parsons AB, Krogan N, Cagney G, Mai D, Greenblatt J, Boone C, Emili A, Houry WA.

Cell. 2005 Mar 11;120(5):715-27.

PMID:
15766533
[PubMed - indexed for MEDLINE]
Free Article
13.

In vivo robustness analysis of cell division cycle genes in Saccharomyces cerevisiae.

Moriya H, Shimizu-Yoshida Y, Kitano H.

PLoS Genet. 2006 Jul;2(7):e111. Epub 2006 Jun 5. Erratum in: PLoS Genet. 2006 Dec;2(12):e218.

PMID:
16839182
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Genome-wide deletion mutant analysis reveals genes required for respiratory growth, mitochondrial genome maintenance and mitochondrial protein synthesis in Saccharomyces cerevisiae.

Merz S, Westermann B.

Genome Biol. 2009;10(9):R95. doi: 10.1186/gb-2009-10-9-r95. Epub 2009 Sep 14.

PMID:
19751518
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Functional profiling of the Saccharomyces cerevisiae genome.

Giaever G, Chu AM, Ni L, Connelly C, Riles L, Véronneau S, Dow S, Lucau-Danila A, Anderson K, André B, Arkin AP, Astromoff A, El-Bakkoury M, Bangham R, Benito R, Brachat S, Campanaro S, Curtiss M, Davis K, Deutschbauer A, Entian KD, Flaherty P, Foury F, Garfinkel DJ, Gerstein M, Gotte D, Güldener U, Hegemann JH, Hempel S, Herman Z, Jaramillo DF, Kelly DE, Kelly SL, Kötter P, LaBonte D, Lamb DC, Lan N, Liang H, Liao H, Liu L, Luo C, Lussier M, Mao R, Menard P, Ooi SL, Revuelta JL, Roberts CJ, Rose M, Ross-Macdonald P, Scherens B, Schimmack G, Shafer B, Shoemaker DD, Sookhai-Mahadeo S, Storms RK, Strathern JN, Valle G, Voet M, Volckaert G, Wang CY, Ward TR, Wilhelmy J, Winzeler EA, Yang Y, Yen G, Youngman E, Yu K, Bussey H, Boeke JD, Snyder M, Philippsen P, Davis RW, Johnston M.

Nature. 2002 Jul 25;418(6896):387-91.

PMID:
12140549
[PubMed - indexed for MEDLINE]
16.

Finding friends and enemies in an enemies-only network: a graph diffusion kernel for predicting novel genetic interactions and co-complex membership from yeast genetic interactions.

Qi Y, Suhail Y, Lin YY, Boeke JD, Bader JS.

Genome Res. 2008 Dec;18(12):1991-2004. doi: 10.1101/gr.077693.108. Epub 2008 Oct 2.

PMID:
18832443
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

A systematic library for comprehensive overexpression screens in Saccharomyces cerevisiae.

Jones GM, Stalker J, Humphray S, West A, Cox T, Rogers J, Dunham I, Prelich G.

Nat Methods. 2008 Mar;5(3):239-41. doi: 10.1038/nmeth.1181. Epub 2008 Feb 3.

PMID:
18246075
[PubMed - indexed for MEDLINE]
18.

The YCR079w gene confers a rapamycin-resistant function and encodes the sixth type 2C protein phosphatase in Saccharomyces cerevisiae.

Ruan H, Yan Z, Sun H, Jiang L.

FEMS Yeast Res. 2007 Mar;7(2):209-15. Epub 2006 Sep 27.

PMID:
17002782
[PubMed - indexed for MEDLINE]
19.

Different sets of QTLs influence fitness variation in yeast.

Romano GH, Gurvich Y, Lavi O, Ulitsky I, Shamir R, Kupiec M.

Mol Syst Biol. 2010;6:346. doi: 10.1038/msb.2010.1. Epub 2010 Feb 16.

PMID:
20160707
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Chemical-genetic approaches for exploring the mode of action of natural products.

Lopez A, Parsons AB, Nislow C, Giaever G, Boone C.

Prog Drug Res. 2008;66:237, 239-71. Review.

PMID:
18416308
[PubMed - indexed for MEDLINE]

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