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Results: 1 to 20 of 98

1.

FitSNPs: highly differentially expressed genes are more likely to have variants associated with disease.

Chen R, Morgan AA, Dudley J, Deshpande T, Li L, Kodama K, Chiang AP, Butte AJ.

Genome Biol. 2008;9(12):R170. doi: 10.1186/gb-2008-9-12-r170. Epub 2008 Dec 5.

PMID:
19061490
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Integration of disease-specific single nucleotide polymorphisms, expression quantitative trait loci and coexpression networks reveal novel candidate genes for type 2 diabetes.

Kang HP, Yang X, Chen R, Zhang B, Corona E, Schadt EE, Butte AJ.

Diabetologia. 2012 Aug;55(8):2205-13. doi: 10.1007/s00125-012-2568-3. Epub 2012 May 16.

PMID:
22584726
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Prioritizing genes for follow-up from genome wide association studies using information on gene expression in tissues relevant for type 2 diabetes mellitus.

Parikh H, Lyssenko V, Groop LC.

BMC Med Genomics. 2009 Dec 31;2:72. doi: 10.1186/1755-8794-2-72.

PMID:
20043853
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Replication of past candidate loci for common diseases and phenotypes in 100 genome-wide association studies.

Siontis KC, Patsopoulos NA, Ioannidis JP.

Eur J Hum Genet. 2010 Jul;18(7):832-7. doi: 10.1038/ejhg.2010.26. Epub 2010 Mar 17.

PMID:
20234392
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Detecting purely epistatic multi-locus interactions by an omnibus permutation test on ensembles of two-locus analyses.

Wongseree W, Assawamakin A, Piroonratana T, Sinsomros S, Limwongse C, Chaiyaratana N.

BMC Bioinformatics. 2009 Sep 17;10:294. doi: 10.1186/1471-2105-10-294.

PMID:
19761607
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Application of gene network analysis techniques identifies AXIN1/PDIA2 and endoglin haplotypes associated with bicuspid aortic valve.

Wooten EC, Iyer LK, Montefusco MC, Hedgepeth AK, Payne DD, Kapur NK, Housman DE, Mendelsohn ME, Huggins GS.

PLoS One. 2010 Jan 21;5(1):e8830. doi: 10.1371/journal.pone.0008830.

PMID:
20098615
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Extreme evolutionary disparities seen in positive selection across seven complex diseases.

Corona E, Dudley JT, Butte AJ.

PLoS One. 2010 Aug 17;5(8):e12236. doi: 10.1371/journal.pone.0012236.

PMID:
20808933
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Comparison of automated candidate gene prediction systems using genes implicated in type 2 diabetes by genome-wide association studies.

Teber ET, Liu JY, Ballouz S, Fatkin D, Wouters MA.

BMC Bioinformatics. 2009 Jan 30;10 Suppl 1:S69. doi: 10.1186/1471-2105-10-S1-S69.

PMID:
19208173
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

SNPranker 2.0: a gene-centric data mining tool for diseases associated SNP prioritization in GWAS.

Merelli I, Calabria A, Cozzi P, Viti F, Mosca E, Milanesi L.

BMC Bioinformatics. 2013;14 Suppl 1:S9. doi: 10.1186/1471-2105-14-S1-S9. Epub 2013 Jan 14.

PMID:
23369106
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Genome-wide SNPs and re-sequencing of growth habit and inflorescence genes in barley: implications for association mapping in germplasm arrays varying in size and structure.

Cuesta-Marcos A, Szucs P, Close TJ, Filichkin T, Muehlbauer GJ, Smith KP, Hayes PM.

BMC Genomics. 2010 Dec 15;11:707. doi: 10.1186/1471-2164-11-707.

PMID:
21159198
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Interrogating type 2 diabetes genome-wide association data using a biological pathway-based approach.

Perry JR, McCarthy MI, Hattersley AT, Zeggini E; Wellcome Trust Case Control Consortium, Weedon MN, Frayling TM.

Diabetes. 2009 Jun;58(6):1463-7. doi: 10.2337/db08-1378. Epub 2009 Feb 27.

PMID:
19252133
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Highly interconnected genes in disease-specific networks are enriched for disease-associated polymorphisms.

Barrenäs F, Chavali S, Alves AC, Coin L, Jarvelin MR, Jörnsten R, Langston MA, Ramasamy A, Rogers G, Wang H, Benson M.

Genome Biol. 2012 Jun 15;13(6):R46. doi: 10.1186/gb-2012-13-6-r46.

PMID:
22703998
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Liver and adipose expression associated SNPs are enriched for association to type 2 diabetes.

Zhong H, Beaulaurier J, Lum PY, Molony C, Yang X, Macneil DJ, Weingarth DT, Zhang B, Greenawalt D, Dobrin R, Hao K, Woo S, Fabre-Suver C, Qian S, Tota MR, Keller MP, Kendziorski CM, Yandell BS, Castro V, Attie AD, Kaplan LM, Schadt EE.

PLoS Genet. 2010 May 6;6(5):e1000932. doi: 10.1371/journal.pgen.1000932.

PMID:
20463879
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Gene, pathway and network frameworks to identify epistatic interactions of single nucleotide polymorphisms derived from GWAS data.

Liu Y, Maxwell S, Feng T, Zhu X, Elston RC, Koyutürk M, Chance MR.

BMC Syst Biol. 2012;6 Suppl 3:S15. doi: 10.1186/1752-0509-6-S3-S15. Epub 2012 Dec 17.

PMID:
23281810
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

GWAS meets microarray: are the results of genome-wide association studies and gene-expression profiling consistent? Prostate cancer as an example.

Gorlov IP, Gallick GE, Gorlova OY, Amos C, Logothetis CJ.

PLoS One. 2009 Aug 4;4(8):e6511. doi: 10.1371/journal.pone.0006511.

PMID:
19652704
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Integrating pathway analysis and genetics of gene expression for genome-wide association studies.

Zhong H, Yang X, Kaplan LM, Molony C, Schadt EE.

Am J Hum Genet. 2010 Apr 9;86(4):581-91. doi: 10.1016/j.ajhg.2010.02.020. Epub 2010 Mar 25.

PMID:
20346437
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Genome-wide meta-analysis of genetic susceptible genes for Type 2 Diabetes.

Hale PJ, López-Yunez AM, Chen JY.

BMC Syst Biol. 2012;6 Suppl 3:S16. doi: 10.1186/1752-0509-6-S3-S16. Epub 2012 Dec 17.

PMID:
23281828
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Genetic variants on 3q21 and in the Sp8 transcription factor gene (SP8) as susceptibility loci for psychotic disorders: a genetic association study.

Kondo K, Ikeda M, Kajio Y, Saito T, Iwayama Y, Aleksic B, Yamada K, Toyota T, Hattori E, Ujike H, Inada T, Kunugi H, Kato T, Yoshikawa T, Ozaki N, Iwata N.

PLoS One. 2013 Aug 13;8(8):e70964. doi: 10.1371/journal.pone.0070964. eCollection 2013.

PMID:
23967141
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Expression QTL analysis of top loci from GWAS meta-analysis highlights additional schizophrenia candidate genes.

de Jong S, van Eijk KR, Zeegers DW, Strengman E, Janson E, Veldink JH, van den Berg LH, Cahn W, Kahn RS, Boks MP, Ophoff RA; PGC Schizophrenia (GWAS) Consortium.

Eur J Hum Genet. 2012 Sep;20(9):1004-8. doi: 10.1038/ejhg.2012.38. Epub 2012 Mar 21.

PMID:
22433715
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Gene prioritization based on biological plausibility over genome wide association studies renders new loci associated with type 2 diabetes.

Sookoian S, Gianotti TF, Schuman M, Pirola CJ.

Genet Med. 2009 May;11(5):338-43. doi: 10.1097/GIM.0b013e31819995ca.

PMID:
19346957
[PubMed - indexed for MEDLINE]

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