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Results: 1 to 20 of 98

1.

Model-driven analysis of experimentally determined growth phenotypes for 465 yeast gene deletion mutants under 16 different conditions.

Snitkin ES, Dudley AM, Janse DM, Wong K, Church GM, Segrè D.

Genome Biol. 2008;9(9):R140. doi: 10.1186/gb-2008-9-9-r140. Epub 2008 Sep 22.

PMID:
18808699
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Epistatic interaction maps relative to multiple metabolic phenotypes.

Snitkin ES, Segrè D.

PLoS Genet. 2011 Feb 10;7(2):e1001294. doi: 10.1371/journal.pgen.1001294.

PMID:
21347328
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Large-scale 13C-flux analysis reveals mechanistic principles of metabolic network robustness to null mutations in yeast.

Blank LM, Kuepfer L, Sauer U.

Genome Biol. 2005;6(6):R49. Epub 2005 May 17.

PMID:
15960801
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Optimality criteria for the prediction of metabolic fluxes in yeast mutants.

Snitkin ES, Segrè D.

Genome Inform. 2008;20:123-34.

PMID:
19425128
[PubMed - indexed for MEDLINE]
5.

Integration of metabolic modeling and phenotypic data in evaluation and improvement of ethanol production using respiration-deficient mutants of Saccharomyces cerevisiae.

Dikicioglu D, Pir P, Onsan ZI, Ulgen KO, Kirdar B, Oliver SG.

Appl Environ Microbiol. 2008 Sep;74(18):5809-16. doi: 10.1128/AEM.00009-08. Epub 2008 Jun 27.

PMID:
18586960
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Linking high-resolution metabolic flux phenotypes and transcriptional regulation in yeast modulated by the global regulator Gcn4p.

Moxley JF, Jewett MC, Antoniewicz MR, Villas-Boas SG, Alper H, Wheeler RT, Tong L, Hinnebusch AG, Ideker T, Nielsen J, Stephanopoulos G.

Proc Natl Acad Sci U S A. 2009 Apr 21;106(16):6477-82. doi: 10.1073/pnas.0811091106. Epub 2009 Apr 3.

PMID:
19346491
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Evolutionary programming as a platform for in silico metabolic engineering.

Patil KR, Rocha I, Förster J, Nielsen J.

BMC Bioinformatics. 2005 Dec 23;6:308.

PMID:
16375763
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Integrated analysis of regulatory and metabolic networks reveals novel regulatory mechanisms in Saccharomyces cerevisiae.

Herrgård MJ, Lee BS, Portnoy V, Palsson BØ.

Genome Res. 2006 May;16(5):627-35. Epub 2006 Apr 10.

PMID:
16606697
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Metabolic functions of duplicate genes in Saccharomyces cerevisiae.

Kuepfer L, Sauer U, Blank LM.

Genome Res. 2005 Oct;15(10):1421-30.

PMID:
16204195
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Connecting extracellular metabolomic measurements to intracellular flux states in yeast.

Mo ML, Palsson BO, Herrgård MJ.

BMC Syst Biol. 2009 Mar 25;3:37. doi: 10.1186/1752-0509-3-37.

PMID:
19321003
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Integrated analysis of metabolic phenotypes in Saccharomyces cerevisiae.

Duarte NC, Palsson BØ, Fu P.

BMC Genomics. 2004 Sep 8;5:63.

PMID:
15355549
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Genome-scale reconstruction and analysis of the metabolic network in the hyperthermophilic archaeon Sulfolobus solfataricus.

Ulas T, Riemer SA, Zaparty M, Siebers B, Schomburg D.

PLoS One. 2012;7(8):e43401. doi: 10.1371/journal.pone.0043401. Epub 2012 Aug 31.

PMID:
22952675
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

The genome-scale metabolic model iIN800 of Saccharomyces cerevisiae and its validation: a scaffold to query lipid metabolism.

Nookaew I, Jewett MC, Meechai A, Thammarongtham C, Laoteng K, Cheevadhanarak S, Nielsen J, Bhumiratana S.

BMC Syst Biol. 2008 Aug 7;2:71. doi: 10.1186/1752-0509-2-71.

PMID:
18687109
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Plasticity of genetic interactions in metabolic networks of yeast.

Harrison R, Papp B, Pál C, Oliver SG, Delneri D.

Proc Natl Acad Sci U S A. 2007 Feb 13;104(7):2307-12. Epub 2007 Feb 6.

PMID:
17284612
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Metabolic pathway analysis of yeast strengthens the bridge between transcriptomics and metabolic networks.

Cakir T, Kirdar B, Ulgen KO.

Biotechnol Bioeng. 2004 May 5;86(3):251-60.

PMID:
15083505
[PubMed - indexed for MEDLINE]
16.

Genome-level transcription data of Yersinia pestis analyzed with a new metabolic constraint-based approach.

Navid A, Almaas E.

BMC Syst Biol. 2012 Dec 6;6:150. doi: 10.1186/1752-0509-6-150.

PMID:
23216785
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Anaerobic and aerobic batch cultivations of Saccharomyces cerevisiae mutants impaired in glycerol synthesis.

Nissen TL, Hamann CW, Kielland-Brandt MC, Nielsen J, Villadsen J.

Yeast. 2000 Mar 30;16(5):463-74.

PMID:
10705374
[PubMed - indexed for MEDLINE]
18.

Continuous modeling of metabolic networks with gene regulation in yeast and in vivo determination of rate parameters.

Moisset P, Vaisman D, Cintolesi A, Urrutia J, Rapaport I, Andrews BA, Asenjo JA.

Biotechnol Bioeng. 2012 Sep;109(9):2325-39. doi: 10.1002/bit.24503. Epub 2012 Apr 24.

PMID:
22447363
[PubMed - indexed for MEDLINE]
19.

Saccharomyces cerevisiae phenotypes can be predicted by using constraint-based analysis of a genome-scale reconstructed metabolic network.

Famili I, Forster J, Nielsen J, Palsson BO.

Proc Natl Acad Sci U S A. 2003 Nov 11;100(23):13134-9. Epub 2003 Oct 24.

PMID:
14578455
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Large-scale evaluation of in silico gene deletions in Saccharomyces cerevisiae.

Förster J, Famili I, Palsson BO, Nielsen J.

OMICS. 2003 Summer;7(2):193-202.

PMID:
14506848
[PubMed - indexed for MEDLINE]

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