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Results: 1 to 20 of 77

1.

Inhibition of casein kinase 1-epsilon induces cancer-cell-selective, PERIOD2-dependent growth arrest.

Yang WS, Stockwell BR.

Genome Biol. 2008;9(6):R92. doi: 10.1186/gb-2008-9-6-r92. Epub 2008 Jun 2.

PMID:
18518968
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

IC261 induces cell cycle arrest and apoptosis of human cancer cells via CK1δ/ɛ and Wnt/β-catenin independent inhibition of mitotic spindle formation.

Cheong JK, Nguyen TH, Wang H, Tan P, Voorhoeve PM, Lee SH, Virshup DM.

Oncogene. 2011 Jun 2;30(22):2558-69. doi: 10.1038/onc.2010.627. Epub 2011 Jan 24.

PMID:
21258417
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

IC261, a specific inhibitor of the protein kinases casein kinase 1-delta and -epsilon, triggers the mitotic checkpoint and induces p53-dependent postmitotic effects.

Behrend L, Milne DM, Stöter M, Deppert W, Campbell LE, Meek DW, Knippschild U.

Oncogene. 2000 Nov 9;19(47):5303-13.

PMID:
11103931
[PubMed - indexed for MEDLINE]
Free Article
4.

Down regulation of circadian clock gene Period 2 accelerates breast cancer growth by altering its daily growth rhythm.

Yang X, Wood PA, Oh EY, Du-Quiton J, Ansell CM, Hrushesky WJ.

Breast Cancer Res Treat. 2009 Sep;117(2):423-31. doi: 10.1007/s10549-008-0133-z. Epub 2008 Jul 24.

PMID:
18651214
[PubMed - indexed for MEDLINE]
5.

An inhibitor of casein kinase I epsilon induces phase delays in circadian rhythms under free-running and entrained conditions.

Badura L, Swanson T, Adamowicz W, Adams J, Cianfrogna J, Fisher K, Holland J, Kleiman R, Nelson F, Reynolds L, St Germain K, Schaeffer E, Tate B, Sprouse J.

J Pharmacol Exp Ther. 2007 Aug;322(2):730-8. Epub 2007 May 14.

PMID:
17502429
[PubMed - indexed for MEDLINE]
Free Article
6.

Clock gene mouse period2 overexpression inhibits growth of human pancreatic cancer cells and has synergistic effect with cisplatin.

Oda A, Katayose Y, Yabuuchi S, Yamamoto K, Mizuma M, Shirasou S, Onogawa T, Ohtsuka H, Yoshida H, Hayashi H, Rikiyama T, Kim H, Choe Y, Kim K, Son H, Motoi F, Egawa S, Unno M.

Anticancer Res. 2009 Apr;29(4):1201-9.

PMID:
19414365
[PubMed - indexed for MEDLINE]
Free Article
7.

The circadian gene per1 plays an important role in cell growth and DNA damage control in human cancer cells.

Gery S, Komatsu N, Baldjyan L, Yu A, Koo D, Koeffler HP.

Mol Cell. 2006 May 5;22(3):375-82.

PMID:
16678109
[PubMed - indexed for MEDLINE]
Free Article
8.

Reversible protein phosphorylation regulates circadian rhythms.

Virshup DM, Eide EJ, Forger DB, Gallego M, Harnish EV.

Cold Spring Harb Symp Quant Biol. 2007;72:413-20. doi: 10.1101/sqb.2007.72.048. Review.

PMID:
18419299
[PubMed - indexed for MEDLINE]
9.

Beta-TrCP1-mediated degradation of PERIOD2 is essential for circadian dynamics.

Reischl S, Vanselow K, Westermark PO, Thierfelder N, Maier B, Herzel H, Kramer A.

J Biol Rhythms. 2007 Oct;22(5):375-86.

PMID:
17876059
[PubMed - indexed for MEDLINE]
10.

CK1epsilon is required for breast cancers dependent on beta-catenin activity.

Kim SY, Dunn IF, Firestein R, Gupta P, Wardwell L, Repich K, Schinzel AC, Wittner B, Silver SJ, Root DE, Boehm JS, Ramaswamy S, Lander ES, Hahn WC.

PLoS One. 2010 Feb 1;5(2):e8979. doi: 10.1371/journal.pone.0008979.

PMID:
20126544
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Casein kinase 1 delta regulates the pace of the mammalian circadian clock.

Etchegaray JP, Machida KK, Noton E, Constance CM, Dallmann R, Di Napoli MN, DeBruyne JP, Lambert CM, Yu EA, Reppert SM, Weaver DR.

Mol Cell Biol. 2009 Jul;29(14):3853-66. doi: 10.1128/MCB.00338-09. Epub 2009 May 4.

PMID:
19414593
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

PERIOD2 is a circadian negative regulator of PAI-1 gene expression in mice.

Oishi K, Miyazaki K, Uchida D, Ohkura N, Wakabayashi M, Doi R, Matsuda J, Ishida N.

J Mol Cell Cardiol. 2009 Apr;46(4):545-52. doi: 10.1016/j.yjmcc.2009.01.001. Epub 2009 Jan 10.

PMID:
19168071
[PubMed - indexed for MEDLINE]
13.

Anti-apoptotic and growth-stimulatory functions of CK1 delta and epsilon in ductal adenocarcinoma of the pancreas are inhibited by IC261 in vitro and in vivo.

Brockschmidt C, Hirner H, Huber N, Eismann T, Hillenbrand A, Giamas G, Radunsky B, Ammerpohl O, Bohm B, Henne-Bruns D, Kalthoff H, Leithäuser F, Trauzold A, Knippschild U.

Gut. 2008 Jun;57(6):799-806. doi: 10.1136/gut.2007.123695. Epub 2008 Jan 18.

PMID:
18203806
[PubMed - indexed for MEDLINE]
14.

Selective inhibition of casein kinase 1 epsilon minimally alters circadian clock period.

Walton KM, Fisher K, Rubitski D, Marconi M, Meng QJ, Sládek M, Adams J, Bass M, Chandrasekaran R, Butler T, Griffor M, Rajamohan F, Serpa M, Chen Y, Claffey M, Hastings M, Loudon A, Maywood E, Ohren J, Doran A, Wager TT.

J Pharmacol Exp Ther. 2009 Aug;330(2):430-9. doi: 10.1124/jpet.109.151415. Epub 2009 May 19.

PMID:
19458106
[PubMed - indexed for MEDLINE]
Free Article
15.

Improved tumor control through circadian clock induction by Seliciclib, a cyclin-dependent kinase inhibitor.

Iurisci I, Filipski E, Reinhardt J, Bach S, Gianella-Borradori A, Iacobelli S, Meijer L, Lévi F.

Cancer Res. 2006 Nov 15;66(22):10720-8.

PMID:
17108108
[PubMed - indexed for MEDLINE]
Free Article
16.

Casein kinase I in the mammalian circadian clock.

Eide EJ, Kang H, Crapo S, Gallego M, Virshup DM.

Methods Enzymol. 2005;393:408-18.

PMID:
15817302
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Casein kinase 1δ activity: a key element in the zebrafish circadian timing system.

Smadja Storz S, Tovin A, Mracek P, Alon S, Foulkes NS, Gothilf Y.

PLoS One. 2013;8(1):e54189. doi: 10.1371/journal.pone.0054189. Epub 2013 Jan 21.

PMID:
23349822
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Casein kinase I epsilon does not rescue double-time function in Drosophila despite evolutionarily conserved roles in the circadian clock.

Sekine T, Yamaguchi T, Hamano K, Young MW, Shimoda M, Saez L.

J Biol Rhythms. 2008 Feb;23(1):3-15. doi: 10.1177/0748730407311652.

PMID:
18258753
[PubMed - indexed for MEDLINE]
19.

The role of {beta}-TrCP1 and {beta}-TrCP2 in circadian rhythm generation by mediating degradation of clock protein PER2.

Ohsaki K, Oishi K, Kozono Y, Nakayama K, Nakayama KI, Ishida N.

J Biochem. 2008 Nov;144(5):609-18. doi: 10.1093/jb/mvn112. Epub 2008 Sep 8.

PMID:
18782782
[PubMed - indexed for MEDLINE]
20.

A large-scale functional RNAi screen reveals a role for CK2 in the mammalian circadian clock.

Maier B, Wendt S, Vanselow JT, Wallach T, Reischl S, Oehmke S, Schlosser A, Kramer A.

Genes Dev. 2009 Mar 15;23(6):708-18. doi: 10.1101/gad.512209.

PMID:
19299560
[PubMed - indexed for MEDLINE]
Free PMC Article

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