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Results: 1 to 20 of 123

1.

A case study of the reproducibility of transcriptional reporter cell-based RNAi screens in Drosophila.

DasGupta R, Nybakken K, Booker M, Mathey-Prevot B, Gonsalves F, Changkakoty B, Perrimon N.

Genome Biol. 2007;8(9):R203.

PMID:
17903264
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Prevalence of off-target effects in Drosophila RNA interference screens.

Ma Y, Creanga A, Lum L, Beachy PA.

Nature. 2006 Sep 21;443(7109):359-63. Epub 2006 Sep 10.

PMID:
16964239
[PubMed - indexed for MEDLINE]
3.

Off-target effects associated with long dsRNAs in Drosophila RNAi screens.

Moffat J, Reiling JH, Sabatini DM.

Trends Pharmacol Sci. 2007 Apr;28(4):149-51. Epub 2007 Mar 9.

PMID:
17350110
[PubMed - indexed for MEDLINE]
4.

Advances in genome-wide RNAi cellular screens: a case study using the Drosophila JAK/STAT pathway.

Fisher KH, Wright VM, Taylor A, Zeidler MP, Brown S.

BMC Genomics. 2012 Sep 24;13:506. doi: 10.1186/1471-2164-13-506.

PMID:
23006893
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Matter arising: off-targets and genome-scale RNAi screens in Drosophila.

Perrimon N, Mathey-Prevot B.

Fly (Austin). 2007 Jan-Feb;1(1):1-5.

PMID:
18705022
[PubMed - indexed for MEDLINE]
Free Article
6.

Evidence of off-target effects associated with long dsRNAs in Drosophila melanogaster cell-based assays.

Kulkarni MM, Booker M, Silver SJ, Friedman A, Hong P, Perrimon N, Mathey-Prevot B.

Nat Methods. 2006 Oct;3(10):833-8.

PMID:
16964256
[PubMed - indexed for MEDLINE]
7.

Identification of Hedgehog pathway components by RNAi in Drosophila cultured cells.

Lum L, Yao S, Mozer B, Rovescalli A, Von Kessler D, Nirenberg M, Beachy PA.

Science. 2003 Mar 28;299(5615):2039-45.

PMID:
12663920
[PubMed - indexed for MEDLINE]
Free Article
8.

A genomewide screen for components of the RNAi pathway in Drosophila cultured cells.

Dorner S, Lum L, Kim M, Paro R, Beachy PA, Green R.

Proc Natl Acad Sci U S A. 2006 Aug 8;103(32):11880-5. Epub 2006 Aug 1.

PMID:
16882716
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Genome-wide RNAi as a route to gene function in Drosophila.

Kuttenkeuler D, Boutros M.

Brief Funct Genomic Proteomic. 2004 Aug;3(2):168-76. Review.

PMID:
15355598
[PubMed - indexed for MEDLINE]
Free Article
10.

FlyRNAi: the Drosophila RNAi screening center database.

Flockhart I, Booker M, Kiger A, Boutros M, Armknecht S, Ramadan N, Richardson K, Xu A, Perrimon N, Mathey-Prevot B.

Nucleic Acids Res. 2006 Jan 1;34(Database issue):D489-94.

PMID:
16381918
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Drosophila genome-wide RNAi screens: are they delivering the promise?

Mathey-Prevot B, Perrimon N.

Cold Spring Harb Symp Quant Biol. 2006;71:141-8. Review.

PMID:
17381290
[PubMed - indexed for MEDLINE]
12.

False negative rates in Drosophila cell-based RNAi screens: a case study.

Booker M, Samsonova AA, Kwon Y, Flockhart I, Mohr SE, Perrimon N.

BMC Genomics. 2011 Jan 20;12:50. doi: 10.1186/1471-2164-12-50.

PMID:
21251254
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

RNA interference of gene expression (RNAi) in cultured Drosophila cells.

Worby CA, Simonson-Leff N, Dixon JE.

Sci STKE. 2001 Aug 14;2001(95):pl1.

PMID:
11752672
[PubMed - indexed for MEDLINE]
14.

Functional dissection of an innate immune response by a genome-wide RNAi screen.

Foley E, O'Farrell PH.

PLoS Biol. 2004 Aug;2(8):E203. Epub 2004 Jun 22.

PMID:
15221030
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

A novel method for tissue-specific RNAi rescue in Drosophila.

Schulz JG, David G, Hassan BA.

Nucleic Acids Res. 2009 Jul;37(13):e93. doi: 10.1093/nar/gkp450. Epub 2009 May 29.

PMID:
19483100
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Genome-wide screening for gene function using RNAi in mammalian cells.

Cullen LM, Arndt GM.

Immunol Cell Biol. 2005 Jun;83(3):217-23. Review.

PMID:
15877598
[PubMed - indexed for MEDLINE]
17.

A functional genomic analysis of cell morphology using RNA interference.

Kiger AA, Baum B, Jones S, Jones MR, Coulson A, Echeverri C, Perrimon N.

J Biol. 2003;2(4):27. Epub 2003 Oct 1.

PMID:
14527345
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

A network-based integrative approach to prioritize reliable hits from multiple genome-wide RNAi screens in Drosophila.

Wang L, Tu Z, Sun F.

BMC Genomics. 2009 May 12;10:220. doi: 10.1186/1471-2164-10-220.

PMID:
19435510
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Vectors and parameters that enhance the efficacy of RNAi-mediated gene disruption in transgenic Drosophila.

Haley B, Foys B, Levine M.

Proc Natl Acad Sci U S A. 2010 Jun 22;107(25):11435-40. doi: 10.1073/pnas.1006689107. Epub 2010 Jun 4.

PMID:
20534445
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Construction and application of random dsRNA interference library for functional genetic screens in embryonic stem cells.

Cheng X, Jian R.

Methods Mol Biol. 2010;650:65-74. doi: 10.1007/978-1-60761-769-3_5.

PMID:
20686943
[PubMed - indexed for MEDLINE]

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