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Results: 1 to 20 of 102

1.

Evolutionary conservation of regulated longevity assurance mechanisms.

McElwee JJ, Schuster E, Blanc E, Piper MD, Thomas JH, Patel DS, Selman C, Withers DJ, Thornton JM, Partridge L, Gems D.

Genome Biol. 2007;8(7):R132.

PMID:
17612391
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Shared transcriptional signature in Caenorhabditis elegans Dauer larvae and long-lived daf-2 mutants implicates detoxification system in longevity assurance.

McElwee JJ, Schuster E, Blanc E, Thomas JH, Gems D.

J Biol Chem. 2004 Oct 22;279(43):44533-43. Epub 2004 Aug 11.

PMID:
15308663
[PubMed - indexed for MEDLINE]
Free Article
3.

Broad spectrum detoxification: the major longevity assurance process regulated by insulin/IGF-1 signaling?

Gems D, McElwee JJ.

Mech Ageing Dev. 2005 Mar;126(3):381-7. Review.

PMID:
15664624
[PubMed - indexed for MEDLINE]
4.

Transcriptional profiling of MnSOD-mediated lifespan extension in Drosophila reveals a species-general network of aging and metabolic genes.

Curtis C, Landis GN, Folk D, Wehr NB, Hoe N, Waskar M, Abdueva D, Skvortsov D, Ford D, Luu A, Badrinath A, Levine RL, Bradley TJ, Tavaré S, Tower J.

Genome Biol. 2007;8(12):R262.

PMID:
18067683
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Proteomic analyses of Caenorhabditis elegans dauer larvae and long-lived daf-2 mutants implicates a shared detoxification system in longevity assurance.

Jones LM, Staffa K, Perally S, LaCourse EJ, Brophy PM, Hamilton JV.

J Proteome Res. 2010 Jun 4;9(6):2871-81. doi: 10.1021/pr9009639.

PMID:
20392130
[PubMed - indexed for MEDLINE]
6.

Reduced insulin/IGF-1 signalling and human longevity.

van Heemst D, Beekman M, Mooijaart SP, Heijmans BT, Brandt BW, Zwaan BJ, Slagboom PE, Westendorp RG.

Aging Cell. 2005 Apr;4(2):79-85.

PMID:
15771611
[PubMed - indexed for MEDLINE]
7.

The GATA transcription factor egl-27 delays aging by promoting stress resistance in Caenorhabditis elegans.

Xu X, Kim SK.

PLoS Genet. 2012;8(12):e1003108. doi: 10.1371/journal.pgen.1003108. Epub 2012 Dec 13.

PMID:
23271974
[PubMed - indexed for MEDLINE]
Free PMC Article
8.
9.

SHC-1/p52Shc targets the insulin/IGF-1 and JNK signaling pathways to modulate life span and stress response in C. elegans.

Neumann-Haefelin E, Qi W, Finkbeiner E, Walz G, Baumeister R, Hertweck M.

Genes Dev. 2008 Oct 1;22(19):2721-35. doi: 10.1101/gad.478408.

PMID:
18832074
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Direct inhibition of the longevity-promoting factor SKN-1 by insulin-like signaling in C. elegans.

Tullet JM, Hertweck M, An JH, Baker J, Hwang JY, Liu S, Oliveira RP, Baumeister R, Blackwell TK.

Cell. 2008 Mar 21;132(6):1025-38. doi: 10.1016/j.cell.2008.01.030.

PMID:
18358814
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Erratum to "Diapause-associated metabolic traits reiterated in long-lived daf-2 mutants in the nematode Caenorhabditis elegans" [Mech. Ageing Dev. 127 (5) (2006) 458-472].

McElwee JJ, Schuster E, Blanc E, Thornton J, Gems D.

Mech Ageing Dev. 2006 Dec;127(12):922-36.

PMID:
17216712
[PubMed - indexed for MEDLINE]
12.

Lifespan-extending effects of royal jelly and its related substances on the nematode Caenorhabditis elegans.

Honda Y, Fujita Y, Maruyama H, Araki Y, Ichihara K, Sato A, Kojima T, Tanaka M, Nozawa Y, Ito M, Honda S.

PLoS One. 2011;6(8):e23527. doi: 10.1371/journal.pone.0023527. Epub 2011 Aug 9.

PMID:
21858156
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

MicroRNA predictors of longevity in Caenorhabditis elegans.

Pincus Z, Smith-Vikos T, Slack FJ.

PLoS Genet. 2011 Sep;7(9):e1002306. doi: 10.1371/journal.pgen.1002306. Epub 2011 Sep 29.

PMID:
21980307
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

A metabolic signature of long life in Caenorhabditis elegans.

Fuchs S, Bundy JG, Davies SK, Viney JM, Swire JS, Leroi AM.

BMC Biol. 2010 Feb 10;8:14. doi: 10.1186/1741-7007-8-14.

PMID:
20146810
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Insulin/IGF-I-signaling pathway: an evolutionarily conserved mechanism of longevity from yeast to humans.

Barbieri M, Bonafè M, Franceschi C, Paolisso G.

Am J Physiol Endocrinol Metab. 2003 Nov;285(5):E1064-71. Review.

PMID:
14534077
[PubMed - indexed for MEDLINE]
Free Article
16.

Single-gene mutations and healthy ageing in mammals.

Bartke A.

Philos Trans R Soc Lond B Biol Sci. 2011 Jan 12;366(1561):28-34. doi: 10.1098/rstb.2010.0281. Review.

PMID:
21115527
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

SMK-1, an essential regulator of DAF-16-mediated longevity.

Wolff S, Ma H, Burch D, Maciel GA, Hunter T, Dillin A.

Cell. 2006 Mar 10;124(5):1039-53.

PMID:
16530049
[PubMed - indexed for MEDLINE]
Free Article
18.

Discovery of functional gene variants associated with human longevity: opportunities and challenges.

Tazearslan C, Cho M, Suh Y.

J Gerontol A Biol Sci Med Sci. 2012 Apr;67(4):376-83. doi: 10.1093/gerona/glr200. Epub 2011 Dec 7.

PMID:
22156437
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Positive feedback between transcriptional and kinase suppression in nematodes with extraordinary longevity and stress resistance.

Tazearslan C, Ayyadevara S, Bharill P, Shmookler Reis RJ.

PLoS Genet. 2009 Apr;5(4):e1000452. doi: 10.1371/journal.pgen.1000452. Epub 2009 Apr 10.

PMID:
19360094
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Association analyses of insulin signaling pathway gene polymorphisms with healthy aging and longevity in Americans of Japanese ancestry.

Morris BJ, Donlon TA, He Q, Grove JS, Masaki KH, Elliott A, Willcox DC, Willcox BJ.

J Gerontol A Biol Sci Med Sci. 2014 Mar;69(3):270-3. doi: 10.1093/gerona/glt082. Epub 2013 Jun 14.

PMID:
23770741
[PubMed - indexed for MEDLINE]

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