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Results: 1 to 20 of 285

1.

The DNA-repair protein AlkB, EGL-9, and leprecan define new families of 2-oxoglutarate- and iron-dependent dioxygenases.

Aravind L, Koonin EV.

Genome Biol. 2001;2(3):RESEARCH0007. Epub 2001 Feb 19.

PMID:
11276424
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

The selectivity and inhibition of AlkB.

Welford RW, Schlemminger I, McNeill LA, Hewitson KS, Schofield CJ.

J Biol Chem. 2003 Mar 21;278(12):10157-61. Epub 2003 Jan 6.

PMID:
12517755
[PubMed - indexed for MEDLINE]
Free Article
3.

Crystal structures of catalytic complexes of the oxidative DNA/RNA repair enzyme AlkB.

Yu B, Edstrom WC, Benach J, Hamuro Y, Weber PC, Gibney BR, Hunt JF.

Nature. 2006 Feb 16;439(7078):879-84.

PMID:
16482161
[PubMed - indexed for MEDLINE]
4.

DNA repair by bacterial AlkB proteins.

Falnes PØ, Rognes T.

Res Microbiol. 2003 Oct;154(8):531-8. Review.

PMID:
14527653
[PubMed - indexed for MEDLINE]
5.

Changes in protein dynamics of the DNA repair dioxygenase AlkB upon binding of Fe(2+) and 2-oxoglutarate.

Bleijlevens B, Shivarattan T, van den Boom KS, de Haan A, van der Zwan G, Simpson PJ, Matthews SJ.

Biochemistry. 2012 Apr 24;51(16):3334-41. doi: 10.1021/bi201699e. Epub 2012 Apr 9.

PMID:
22443471
[PubMed - indexed for MEDLINE]
6.

Incorporation of oxygen into the succinate co-product of iron(II) and 2-oxoglutarate dependent oxygenases from bacteria, plants and humans.

Welford RW, Kirkpatrick JM, McNeill LA, Puri M, Oldham NJ, Schofield CJ.

FEBS Lett. 2005 Sep 26;579(23):5170-4. Erratum in: FEBS Lett. 2005 Dec 5;579(29):6688.

PMID:
16153644
[PubMed - indexed for MEDLINE]
Free Article
7.

Structure of human phytanoyl-CoA 2-hydroxylase identifies molecular mechanisms of Refsum disease.

McDonough MA, Kavanagh KL, Butler D, Searls T, Oppermann U, Schofield CJ.

J Biol Chem. 2005 Dec 9;280(49):41101-10. Epub 2005 Sep 25.

PMID:
16186124
[PubMed - indexed for MEDLINE]
Free Article
8.

AlkB-mediated oxidative demethylation reverses DNA damage in Escherichia coli.

Falnes PØ, Johansen RF, Seeberg E.

Nature. 2002 Sep 12;419(6903):178-82.

PMID:
12226668
[PubMed - indexed for MEDLINE]
9.

Prediction of novel families of enzymes involved in oxidative and other complex modifications of bases in nucleic acids.

Iyer LM, Tahiliani M, Rao A, Aravind L.

Cell Cycle. 2009 Jun 1;8(11):1698-710. Epub 2009 Jun 27.

PMID:
19411852
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Schizosaccharomyces pombe Ofd2 is a nuclear 2-oxoglutarate and iron dependent dioxygenase interacting with histones.

Korvald H, Mølstad Moe AM, Cederkvist FH, Thiede B, Laerdahl JK, Bjørås M, Alseth I.

PLoS One. 2011;6(9):e25188. doi: 10.1371/journal.pone.0025188. Epub 2011 Sep 16.

PMID:
21949882
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Human ABH3 structure and key residues for oxidative demethylation to reverse DNA/RNA damage.

Sundheim O, Vågbø CB, Bjørås M, Sousa MM, Talstad V, Aas PA, Drabløs F, Krokan HE, Tainer JA, Slupphaug G.

EMBO J. 2006 Jul 26;25(14):3389-97. Epub 2006 Jul 6.

PMID:
16858410
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Bioinformatic mapping of AlkB homology domains in viruses.

Bratlie MS, Drabløs F.

BMC Genomics. 2005 Jan 3;6:1.

PMID:
15627404
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

The phosphatidylserine receptor from Hydra is a nuclear protein with potential Fe(II) dependent oxygenase activity.

Cikala M, Alexandrova O, David CN, Pröschel M, Stiening B, Cramer P, Böttger A.

BMC Cell Biol. 2004 Jun 11;5:26.

PMID:
15193161
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Structural origins of the selectivity of the trifunctional oxygenase clavaminic acid synthase.

Zhang Z, Ren J, Stammers DK, Baldwin JE, Harlos K, Schofield CJ.

Nat Struct Biol. 2000 Feb;7(2):127-33.

PMID:
10655615
[PubMed - indexed for MEDLINE]
15.

Preparation and characterization of the native iron(II)-containing DNA repair AlkB protein directly from Escherichia coli.

Mishina Y, Chen LX, He C.

J Am Chem Soc. 2004 Dec 29;126(51):16930-6.

PMID:
15612731
[PubMed - indexed for MEDLINE]
16.

Molecular cloning and functional analysis of a human cDNA encoding an Escherichia coli AlkB homolog, a protein involved in DNA alkylation damage repair.

Wei YF, Carter KC, Wang RP, Shell BK.

Nucleic Acids Res. 1996 Mar 1;24(5):931-37.

PMID:
8600462
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Genomic structure and expression of Jmjd6 and evolutionary analysis in the context of related JmjC domain containing proteins.

Hahn P, Böse J, Edler S, Lengeling A.

BMC Genomics. 2008 Jun 18;9:293. doi: 10.1186/1471-2164-9-293.

PMID:
18564434
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Crystal structure of a clavaminate synthase-Fe(II)-2-oxoglutarate-substrate-NO complex: evidence for metal centered rearrangements.

Zhang Z, Ren Js, Harlos K, McKinnon CH, Clifton IJ, Schofield CJ.

FEBS Lett. 2002 Apr 24;517(1-3):7-12.

PMID:
12062399
[PubMed - indexed for MEDLINE]
Free Article
19.

Crystal structure of PHYHD1A, a 2OG oxygenase related to phytanoyl-CoA hydroxylase.

Zhang Z, Kochan GT, Ng SS, Kavanagh KL, Oppermann U, Schofield CJ, McDonough MA.

Biochem Biophys Res Commun. 2011 May 20;408(4):553-8. doi: 10.1016/j.bbrc.2011.04.059. Epub 2011 Apr 21.

PMID:
21530488
[PubMed - indexed for MEDLINE]
20.

Phylogenomic identification of five new human homologs of the DNA repair enzyme AlkB.

Kurowski MA, Bhagwat AS, Papaj G, Bujnicki JM.

BMC Genomics. 2003 Dec 10;4(1):48.

PMID:
14667252
[PubMed - indexed for MEDLINE]
Free PMC Article

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